Abstract: Various techniques to start the sequential DC fast charging process of an electric machine and then switch to AC charging of the electric machine at a given state of charge percentage while also starting to DC fast charge another electric machine in the fleet.

Abstract: A computer-implemented method of planning a path for a mobile robot in the presence of a set of obstacles comprises: computing for each obstacle a probabilistic obstacle position distribution; computing at least one path-independent function as a combination of the probabilistic obstacle position distributions; and for at least one candidate path, determining an upper bound on the total probability of obstacle collision along that path, by aggregating the path-independent function based on an area defined by the candidate path and a mobile robot shape, wherein the path-independent function is independent of the candidate path.

Abstract: A method is provided for identifying an anomaly in a communications network, the communications network covering a geographical area. The method comprises defining a plurality of regions within the geographical area. A measurement of a network performance characteristic is received from a user equipment, UE, connected to the communications network. The measurement is associated with a geographical location. A region of the plurality of regions which contains the geographical location is identified, and it is determined that there is an anomaly in the communications network within the identified region.

Abstract: Disclosed are analogues of hinokitiol, methods for preparing them, and pharmaceutical compositions thereof. Also disclosed are methods for their use in treating iron-related diseases.

Abstract: A first aspect of the invention provides a method of fault monitoring in a utility supply network, the method comprising: receiving user queries, each user query about a performance of the network at a respective location; defining a region based on the locations specified in the received user queries; determining an estimate of a user population in the region; and according the region, based on the estimate, a priority for one or more of fault investigation and remediation.

Abstract: A patient interface face contact element comprises a surface for contacting the face of a patient, and a connection face for coupling the patient interface face contact element to a support using a magnetic coupling. The support is also provided as well as the complete patient interface. Headgear strap clips can also be retained magnetically.

Abstract: A disposable staining system is provided including an insertable module configured to receive a biological sample therein, the insertable module including a well in which the biological sample is positioned; and a staining cartridge configured to receive the insertable module including the biological sample therein, the insertable module being positioned in the staining cartridge. The insertable module has first and second inclined planes on opposing sides of an upper surface of the insertable module. A sled configured to receive the insertable module has corresponding first and second inclined planes on a bottom surface thereof. The first and second inclined planes of the insertable module and the first and second inclined planes of the sled are configured to transform horizontal movement of the insertable module into the staining cartridge into a vertical movement of the sled such that the sled is pushed upward.

Abstract: A patient interface face contact element includes a surface for contacting the face of a patient and a connection face for coupling the patient interface face contact element to a support using a magnetic coupling. The support is also provided as well as the complete patient interface. Headgear strap clips can also be retained magnetically.

Abstract: A first aspect of the invention provides a method of fault monitoring in a utility supply network, the method comprising: receiving user queries, each user query about a performance of the network at a respective location; defining a region based on the locations specified in the received user queries; determining an estimate of a user population in the region; and according the region, based on the estimate, a priority for one or more of fault investigation and remediation.

Abstract: A first aspect of the invention provides a method of fault monitoring in a utility supply network, the method comprising: receiving user queries, each user query about a performance of the network at a respective location; defining a region based on the locations specified in the received user queries; determining an estimate of a user population in the region; and according the region, based on the estimate, a priority for one or more of fault investigation and remediation.

Abstract: The present disclosure describes single agent and combination therapies and uses for the treatment of cancer and/or cancer-associated diseases. The single agent and combinations therapies include a BCMA antibody.

Abstract: The invention provides a computer-implemented method of planning a path for a mobile robot such as an autonomous vehicle in the presence of K obstacles. The method uses, for each of the K obstacles, a shape Bk and a density function pk(x) representing the probabilistic position of the obstacle. The method repeats the following steps for at least two different paths A: —choosing a path A, where A is the swept area of the robot within a given time interval; and—calculating based on the density function of each obstacle and the swept path an upper bound on the total probability of at least one collision FD between the robot and the K obstacles. This allows a number of candidate paths to be ranked for safety. By precomputing factors of the computational steps over K obstacles, the computation per path is O(N), and not O(NK). A safety threshold can be used to filter out paths below that threshold.

Abstract: The present disclosure describes single agent and combination therapies and uses for the treatment of cancer and/or cancer-associated diseases. The single agent and combinations therapies include a BCMA antibody.

Abstract: A first aspect of the invention provides a method of fault monitoring in a utility supply network, the method comprising: receiving user queries, each user query about a performance of the network at a respective location; defining a region based on the locations specified in the received user queries; determining an estimate of a user population in the region; and according the region, based on the estimate, a priority for one or more of fault investigation and remediation.

Abstract: A battery charging device may detect a connection, from a first machine, to receive an electrical charge to charge a battery of the first machine. The battery charging device may receive, via the connection, machine information regarding the first machine. The battery charging device may identify, based on the machine information, a second machine associated with the first machine. The battery charging device may determine a first recommendation associated with the first machine and a second recommendation associated with the second machine. The first recommendation may identify at least one of a component or a service recommended for the first machine. The second recommendation may identify at least one of a component or a service recommended for the second machine. The battery charging device may provide the first recommendation and the second recommendation while providing the electrical charge to the first machine.

Abstract: A method of diagnosing faults in a utility supply network involves receiving performance data indicative of performance of the utility supply network, and receiving historical performance data indicative of a historical performance of the utility supply network and a fault associated with the historical performance data. A fault in the utility supply network is determined based on a comparison of the performance data with the historical performance data.

Abstract: Provided are methods of treating bladder cancer (e.g., urothelial carcinoma, UC) in a subject having bladder cancer, e.g., UC, with an effective dose regimen of an anti-PD-L1 antibody, e.g., durvalumab, or an antigen binding fragment thereof. Also provided are methods in which an anti-PD-L1 antibody is used in combination with another immunotherapeutic agent, e.g., tremelimumab to treat a bladder cancer, e.g., UC, in a subject having bladder cancer. In some cases, the subject undergoing treatment is identified as having a bladder cancer or tumor that is PD-L1-low/neg, or PD-L1-high. Methods are also provided in which anti-PD-L1 antibody treatment of bladder cancer is used following a standard of care or first-line therapy in subjects who have progressed following such therapies or who have relapsed after a prior treatment regimen.

Abstract: A computer-implemented method of planning a path for a mobile robot in the presence of a set of obstacles comprises: computing for each obstacle a probabilistic obstacle position distribution; computing at least one path-independent function as a combination of the probabilistic obstacle position distributions; and for at least one candidate path, determining an upper bound on the total probability of obstacle collision along that path, by aggregating the path-independent function based on an area defined by the candidate path and a mobile robot shape, wherein the path-independent function is independent of the candidate path.

Abstract: A method is provided for identifying an anomaly in a communications network, the communications network covering a geographical area. The method comprises defining a plurality of regions within the geographical area. A measurement of a network performance characteristic is received from a user equipment, UE, connected to the communications network. The measurement is associated with a geographical location. A region of the plurality of regions which contains the geographical location is identified, and it is determined that there is an anomaly in the communications network within the identified region.

Abstract: A computer-implemented method of determining a priority of an incident in a utility supply involves receiving an indication of the incident in the utility supply network, receiving subjective data relating to user perception of performance of the utility supply network and determining a priority of the incident based on the subjective data. Determining the priority may also involve using objective data about the performance of the utility supply network and information about known or planned outages.