Abstract: Enhanced history buffer systems and methods are operable to temporarily store program content for program events. An exemplary embodiment receives program content corresponding to each of the plurality of program events, generates a unique discrete program content file in the enhanced history buffer for each of the plurality of program events, and stores the received program content for each of the plurality of program events in the associated one of the discrete program content files. Each discrete program content file begins at a known starting location in the enhanced history buffer and ends at a known ending location in the enhanced history buffer.

Abstract: Enhanced history buffer systems and methods are operable to temporarily store program content for program events. An exemplary embodiment receives program content corresponding to each of the plurality of program events, generates a unique discrete program content file in the enhanced history buffer for each of the plurality of program events, and stores the received program content for each of the plurality of program events in the associated one of the discrete program content files. Each discrete program content file begins at a known starting location in the enhanced history buffer and ends at a known ending location in the enhanced history buffer.

Abstract: Enhanced history buffer systems and methods are operable to temporarily store program content for program events. An exemplary embodiment receives program content corresponding to each of the plurality of program events, generates a unique discrete program content file in the enhanced history buffer for each of the plurality of program events, and stores the received program content for each of the plurality of program events in the associated one of the discrete program content files. Each discrete program content file begins at a known starting location in the enhanced history buffer and ends at a known ending location in the enhanced history buffer.

Abstract: Enhanced history buffer systems and methods are operable to temporarily store program content for program events. An exemplary embodiment receives program content corresponding to each of the plurality of program events, generates a unique discrete program content file in the enhanced history buffer for each of the plurality of program events, and stores the received program content for each of the plurality of program events in the associated one of the discrete program content files. Each discrete program content file begins at a known starting location in the enhanced history buffer and ends at a known ending location in the enhanced history buffer.

Abstract: Enhanced history buffer systems and methods are operable to temporarily store program content for program events. An exemplary embodiment receives program content corresponding to each of the plurality of program events, generates a unique discrete program content file in the enhanced history buffer for each of the plurality of program events, and stores the received program content for each of the plurality of program events in the associated one of the discrete program content files. Each discrete program content file begins at a known starting location in the enhanced history buffer and ends at a known ending location in the enhanced history buffer.

Abstract: Disclosed herein is the use of aminopyridines, such as 3-aminopyridine, 4-aminopyridine or 3,4-diaminopyridine, in the management and treatment of cerebral palsy patients of all ages.

Abstract: Enhanced history buffer systems and methods are operable to temporarily store program content for program events. An exemplary embodiment receives program content corresponding to each of the plurality of program events, generates a unique discrete program content file in the enhanced history buffer for each of the plurality of program events, and stores the received program content for each of the plurality of program events in the associated one of the discrete program content files. Each discrete program content file begins at a known starting location in the enhanced history buffer and ends at a known ending location in the enhanced history buffer.

Abstract: Enhanced history buffer systems and methods are operable to temporarily store program content for program events. An exemplary embodiment receives program content corresponding to each of the plurality of program events, generates a unique discrete program content file in the enhanced history buffer for each of the plurality of program events, and stores the received program content for each of the plurality of program events in the associated one of the discrete program content files. Each discrete program content file begins at a known starting location in the enhanced history buffer and ends at a known ending location in the enhanced history buffer.

Abstract: The present invention is directed to a method of improving functional recovery following a central nervous system contusion injury. The method includes administering a therapeutically effective amount of glycosaminoglycan degrading enzyme. The glycosaminoglycan degrading enzyme may be dermatan sulfate or chondroitin sulfate degrading enzymes. The central nervous system contusion injury may include a traumatic brain injury or a spinal cord injury. The functional recovery may include autonomic functions, sensory functions, motor functions or the like.

Abstract: A pharmaceutical composition which comprises a therapeutically effective amount of a aminopyridine dispersed in a release matrix, including, for example, a composition that can be formulated into a stable, sustained-release oral dosage formulation, such as a tablet which provides, upon administration to a patient, a therapeutically effective plasma level of the aminopyridine for a period of at least 12 hours, preferably 24 hours or more and the use of the composition to treat various neurological diseases.

Abstract: A pharmaceutical composition which comprises a therapeutically effective amount of a aminopyridine dispersed in a release matrix, including, for example, a composition that can be formulated into a stable, sustained-release oral dosage formulation, such as a tablet which provides, upon administration to a patient, a therapeutically effective plasma level of the aminopyridine for a period of at about 12 hours and the use of the composition to treat various neurological diseases, including multiple sclerosis. A method of selecting individuals based on responsiveness to a treatment, including, for example, identifying individuals who responded to treatment with a sustained release fampridine composition.

Abstract: Apparatus and methods are described for efficient and precise placement of discrete quantities of materials adjacent to the apparatus. The apparatus and methods are particularly adapted for being coupled to a dump truck, receiving material contained in the bed of the dump truck into a hopper, metering the material in the hopper by a receiving conveyor and transferring the metered material from the receiving conveyor to the side of the apparatus by a cross conveyor positioned perpendicularly to the receiving conveyor. A telescoping boom conveyor having a material director transfers the metered material from an end of the cross conveyor and places the metered material adjacent to the apparatus. Attached at the other end of the cross conveyor is a material positioning attachment for positioning the precisely placed material into a level grade or a road curb.