Patents by Inventor Andrew Boyd MACCONNELL

Andrew Boyd MACCONNELL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • OLIGONUCLEOTIDE ENCODED CHEMICAL LIBRARIES, RELATED SYSTEMS, DEVICES, AND METHODS FOR DETECTING, ANALYZING, QUANTIFYING, AND TESTING BIOLOGICS/GENETICS
    Publication number: 20230065224
    Abstract: This application provides a bead with a covalently attached chemical compound and a covalently attached DNA barcode and methods for using such beads. The bead has many substantially identical copies of the chemical compound and many substantially identical copies of the DNA barcode. The compound consists of one or more chemical monomers, where the DNA barcode takes the form of barcode modules, where each module corresponds to and allows identification of a corresponding chemical monomer. The nucleic acid barcode can have a concatenated structure or an orthogonal structure. Provided are a method for sequencing the bead-bound nucleic acid barcode, for cleaving the compound from the bead, and for assessing biological activity of the released compound.
    Type: Application
    Filed: January 28, 2021
    Publication date: March 2, 2023
    Inventors: Kandaswamy VIJAYAN, Kapil MAHAKALKAR, Yi ZHANG, Andrew Boyd MACCONNELL, Joseph Franklin ROKICKI, Michael VAN NGUYEN
  • OLIGONUCLEOTIDE ENCODED CHEMICAL LIBRARIES
    Publication number: 20220025358
    Abstract: This application provides a bead with a covalently attached chemical compound and a covalently attached DNA barcode and methods for using such beads. The bead has many substantially identical copies of the chemical compound and many substantially identical copies of the DNA barcode. The compound consists of one or more chemical monomers, where the DNA barcode takes the form of barcode modules, where each module corresponds to and allows identification of a corresponding chemical monomer. The nucleic acid barcode can have a concatenated structure or an orthogonal structure. Provided are method for sequencing the bead-bound nucleic acid barcode, for cleaving the compound from the bead, and for assessing biological activity of the released compound.
    Type: Application
    Filed: March 12, 2021
    Publication date: January 27, 2022
    Inventors: Kandaswamy VIJAYAN, Andrew Boyd MACCONNELL, Joseph Franklin ROKICKI, Michael VAN NGUYEN
  • OLIGONUCLEOTIDE ENCODED CHEMICAL LIBRARIES
    Publication number: 20200324287
    Abstract: This application provides a bead with a covalently attached chemical compound and a covalently attached DNA barcode and methods for using such beads. The bead has many substantially identical copies of the chemical compound and many substantially identical copies of the DNA barcode. The compound consists of one or more chemical monomers, where the DNA barcode takes the form of barcode modules, where each module corresponds to and allows identification of a corresponding chemical monomer. The nucleic acid barcode can have a concatenated structure or an orthogonal structure. Provided are method for sequencing the bead-bound nucleic acid barcode, for cleaving the compound from the bead, and for assessing biological activity of the released compound.
    Type: Application
    Filed: May 8, 2020
    Publication date: October 15, 2020
    Applicant: Plexium, Inc.
    Inventors: Kandaswamy VIJAYAN, Andrew Boyd MACCONNELL, Joseph Franklin ROKICKI, Michael VAN NGUYEN
  • OLIGONUCLEOTIDE ENCODED CHEMICAL LIBRARIES
    Publication number: 20200001295
    Abstract: This application provides a bead with a covalently attached chemical compound and a covalently attached DNA barcode and methods for using such beads. The bead has many substantially identical copies of the chemical compound and many substantially identical copies of the DNA barcode. The compound consists of one or more chemical monomers, where the DNA barcode takes the form of barcode modules, where each module corresponds to and allows identification of a corresponding chemical monomer. The nucleic acid barcode can have a concatenated structure or an orthogonal structure. Provided are method for sequencing the bead-bound nucleic acid barcode, for cleaving the compound from the bead, and for assessing biological activity of the released compound.
    Type: Application
    Filed: August 7, 2019
    Publication date: January 2, 2020
    Applicant: Plexium, Inc.
    Inventors: Kandaswamy VIJAYAN, Andrew Boyd MACCONNELL, Joseph Franklin ROKICKI
  • OLIGONUCLEOTIDE ENCODED CHEMICAL LIBRARIES
    Publication number: 20190210018
    Abstract: This application provides a bead with a covalently attached chemical compound and a covalently attached DNA barcode and methods for using such beads. The bead has many substantially identical copies of the chemical compound and many substantially identical copies of the DNA barcode. The compound consists of one or more chemical monomers, where the DNA barcode takes the form of barcode modules, where each module corresponds to and allows identification of a corresponding chemical monomer. The nucleic acid barcode can have a concatenated structure or an orthogonal structure. Provided are method for sequencing the bead-bound nucleic acid barcode, for cleaving the compound from the bead, and for assessing biological activity of the released compound.
    Type: Application
    Filed: September 24, 2018
    Publication date: July 11, 2019
    Applicant: Plexium, Inc.
    Inventors: Kandaswamy VIJAYAN, Andrew Boyd MACCONNELL, Joseph Franklin Rokicki, Michael VAN NGUYEN
  • OLIGONUCLEOTIDE ENCODED CHEMICAL LIBRARIES
    Publication number: 20190093103
    Abstract: This application provides a bead with a covalently attached chemical compound and a covalently attached DNA barcode and methods for using such beads. The bead has many substantially identical copies of the chemical compound and many substantially identical copies of the DNA barcode. The compound consists of one or more chemical monomers, where the DNA barcode takes the form of barcode modules, where each module corresponds to and allows identification of a corresponding chemical monomer. The nucleic acid barcode can have a concatenated structure or an orthogonal structure. Provided are method for sequencing the bead-bound nucleic acid barcode, for cleaving the compound from the bead, and for assessing biological activity of the released compound.
    Type: Application
    Filed: September 24, 2018
    Publication date: March 28, 2019
    Applicant: Plexium, Inc.
    Inventors: Kandaswamy VIJAYAN, Andrew Boyd MACCONNELL, Joseph Franklin Rokicki, Michael VAN NGUYEN