Patents by Inventor Andrew Briane ADAMS

Andrew Briane ADAMS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATING TRANSPLANT REJECTION USING A DOMAIN ANTIBODY DIRECTED AGAINST CD40L
    Publication number: 20200231676
    Abstract: Methods of treating renal transplant rejection using anti-CD40L domain antibodies are provided. The anti-CD40L dAbs are less likely to cause platelet aggregation and thus cause thromboembolism. Appropriate anti-CD40L dAbs doses and administration regimens are also provided. Combination treatments for transplant rejection, particularly renal transplant rejection, using anti-CD40L dAbs, a CTLA4 mutant molecule (e.g., belatacept) and/or anti-CD28 optionally with conventional immunosuppressive renal transplant therapy are provided.
    Type: Application
    Filed: January 31, 2020
    Publication date: July 23, 2020
    Inventors: Anish SURI, Steven G. NADLER, Christian P. LARSEN, Andrew Briane ADAMS
  • METHODS OF TREATING TRANSPLANT REJECTION USING A DOMAIN ANTIBODY DIRECTED AGAINST CD40
    Publication number: 20170051059
    Abstract: Methods of treating renal transplant rejection using anti-CD40L domain antibodies are provided. The anti-CD40L dAbs are less likely to cause platelet aggregation and thus cause thromboembolism. Appropriate anti-CD40L dAbs doses and administration regimens are also provided. Combination treatments for transplant rejection, particularly renal transplant rejection, using anti-CD40L dAbs, a CTLA4 mutant molecule (e.g., belatacept) and/or anti-CD28 optionally with conventional immunosuppressive renal transplant therapy are provided.
    Type: Application
    Filed: March 19, 2015
    Publication date: February 23, 2017
    Applicants: Bristol-Myers Squibb Company, Bristol-Myers Squibb Company
    Inventors: Anish SURI, Steven G. NADLER, Christian P. LARSEN, Andrew Briane ADAMS