Patents by Inventor Andrew Bristol

Andrew Bristol has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11952429
    Abstract: The present invention provides for recombinant monoclonal antibodies that bind to human colorectal and pancreatic carcinoma-associated antigens, along with nucleic acid sequences encoding the antibody chains, and the amino acid sequences corresponding to the nucleic acids, and uses for these antibodies, nucleic acids and amino acids.
    Type: Grant
    Filed: June 24, 2022
    Date of Patent: April 9, 2024
    Inventors: J. Andrew Bristol, Judith A. Kantor
  • Publication number: 20240082703
    Abstract: A handheld controller configured to be held by a user's hand. The handheld controller comprising a main body, and a handle extending from the main body, wherein the handle has a palm side and a finger side. A control button is positioned on the main body or handle, and a detection sensor is on the handle. The detection sensor is positioned to detect the presence of the finger or palm of a user's hand engaging the handle. The detection sensor can be a capacitive touch sensor, a proximity sensor or other detection sensor operative to detect the touch or spatial presence of the user's hand or fingers.
    Type: Application
    Filed: November 22, 2023
    Publication date: March 14, 2024
    Inventors: Benjamin Elliott Tunberg Rogoza, Sharvil Shailesh Talati, James Stocker Webb, Yi-yaun Chen, Jason Andrew Higgins, Bradley Morris Johnson, Peter Wesley Bristol
  • Publication number: 20230277466
    Abstract: The present invention provides for a formulation comprising an active alkaline phosphatase (AP)-based agent and an enteric agent, wherein the formulation is suitable for releasing a substantial amount of the active AP-based agent in the intestines.
    Type: Application
    Filed: March 17, 2023
    Publication date: September 7, 2023
    Inventors: Andrew BRISTOL, Ray STAPLETON, Michael KALEKO, Christian FURLAN FREGUIA, Steven HUBERT, Cristina FREIRE, James GUBBINS
  • Publication number: 20230279409
    Abstract: The invention relates to, in part, improved methods for the production of beta-lactamase using Escherichia coli (E. coli) cells. High yield production of beta-lactamase is achieved using methods of the invention.
    Type: Application
    Filed: December 1, 2022
    Publication date: September 7, 2023
    Inventors: Andrew BRISTOL, Michael KALEKO, Steven HUBERT
  • Publication number: 20230203190
    Abstract: The present invention provides for purified or highly pure recombinant monoclonal antibodies that bind to human colorectal and pancreatic carcinoma-associated antigens (CPAA), along with nucleic acid sequences encoding the antibody chains, and the amino acid sequences corresponding to said nucleic acids and uses for said sequences.
    Type: Application
    Filed: December 16, 2022
    Publication date: June 29, 2023
    Inventors: Myron Arlen, J. Andrew Bristol, Ariel Hollinshead, Kwong Tsang
  • Patent number: 11638699
    Abstract: The present invention provides for a formulation comprising an active alkaline phosphatase (AP)-based agent and an enteric agent, wherein the formulation is suitable for releasing a substantial amount of the active AP-based agent in the intestines.
    Type: Grant
    Filed: March 20, 2019
    Date of Patent: May 2, 2023
    Assignee: Theriva Biologics, Inc.
    Inventors: Andrew Bristol, Ray Stapleton, Michael Kaleko, Christian Furlan Freguia, Steven Hubert, Cristina Freire, James Gubbins
  • Patent number: 11572413
    Abstract: The present invention provides for purified or highly pure recombinant monoclonal antibodies that bind to human colorectal and pancreatic carcinoma-associated antigens (CPAA), along with nucleic acid sequences encoding the antibody chains, and the amino acid sequences corresponding to said nucleic acids and uses for said sequences.
    Type: Grant
    Filed: June 12, 2019
    Date of Patent: February 7, 2023
    Assignee: PRECISION BIOLOGICS, INC.
    Inventors: Myron Arlen, J. Andrew Bristol, Ariel Hollinshead, Kwong Tsang
  • Publication number: 20230032624
    Abstract: This invention relates to NPC-1 antigen on the MUC5AC protein and 16C3 antigen on CEACAM5 and CEACAM6 proteins, and 31.1 epitope on the A33 protein are differentially expressed in cancers including, lung cancer, ovarian cancer, pancreas cancer, breast cancer, and colon cancer, and diagnostic and therapeutic usages. Further, NPC-1, 16C3, and/or 31.1 epitope specific antibodies and diagnostic and therapeutic methods of use.
    Type: Application
    Filed: May 9, 2022
    Publication date: February 2, 2023
    Inventors: Xiulian DU, Janos LUKA, Lewis Joe STAFFORD, Mark Semenuk, Xue-Ping WANG, Judith KANTOR, Andrew BRISTOL
  • Patent number: 11542510
    Abstract: The invention relates to, in part, improved methods for the production of beta-lactamase using Escherichia coli (E. coli) cells. High yield production of beta-lactamase is achieved using methods of the invention.
    Type: Grant
    Filed: May 7, 2021
    Date of Patent: January 3, 2023
    Assignee: Synthetic Biologics, Inc.
    Inventors: Andrew Bristol, Michael Kaleko, Steven Hubert
  • Publication number: 20220403045
    Abstract: The present invention provides for recombinant monoclonal antibodies that bind to human colorectal and pancreatic carcinoma-associated antigens, along with nucleic acid sequences encoding the antibody chains, and the amino acid sequences corresponding to the nucleic acids, and uses for these antibodies, nucleic acids and amino acids.
    Type: Application
    Filed: June 24, 2022
    Publication date: December 22, 2022
    Inventors: J. ANDREW BRISTOL, JUDITH A. KANTOR
  • Publication number: 20220323367
    Abstract: The present invention provides, in part, formulations comprising an alkaline phosphatase. Particularly, modified-release formulations comprising an alkaline phosphatase are provided, which release a substantial amount of the alkaline phosphatase in the intestines. Therapeutic uses of the alkaline phosphatase formulations are also provided.
    Type: Application
    Filed: June 3, 2020
    Publication date: October 13, 2022
    Inventors: Michael KALEKO, Ray STAPLETON, Andrew BRISTOL, Steven HUBERT, Cristina FREIRE
  • Patent number: 11401341
    Abstract: The present invention provides for recombinant monoclonal antibodies that bind to human colorectal and pancreatic carcinoma-associated antigens, along with nucleic acid sequences encoding the antibody chains, and the amino acid sequences corresponding to the nucleic acids, and uses for these antibodies, nucleic acids and amino acids.
    Type: Grant
    Filed: February 20, 2020
    Date of Patent: August 2, 2022
    Assignee: PRECISION BIOLOGICS, INC.
    Inventors: J. Andrew Bristol, Judith A. Kantor
  • Patent number: 11345733
    Abstract: This invention relates to NPC-1 antigen on the MUC5AC protein and 16C3 antigen on CEACAM5 and CEACAM6 proteins, and 31.1 epitope on the A33 protein are differentially expressed in cancers including, lung cancer, ovarian cancer, pancreas cancer, breast cancer, and colon cancer, and diagnostic and therapeutic usages. Further, NPC-1, 16C3, and/or 31.1 epitope specific antibodies and diagnostic and therapeutic methods of use.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: May 31, 2022
    Assignee: PRECISION BIOLOGICS, INC.
    Inventors: Xiulian Du, Janos Luka, Lewis Joe Stafford, Mark Semenuk, Xue-Ping Wang, Judith Kantor, Andrew Bristol
  • Publication number: 20210332373
    Abstract: The invention relates to, in part, improved methods for the production of beta-lactamase using Escherichia coli (E. coli) cells. High yield production of beta-lactamase is achieved using methods of the invention.
    Type: Application
    Filed: May 7, 2021
    Publication date: October 28, 2021
    Inventors: Andrew BRISTOL, Michael KALEKO, Steven HUBERT
  • Patent number: 11034966
    Abstract: The invention relates to, in part, improved methods for the production of beta-lactamase using Escherichia coli (E. coli) cells. High yield production of beta-lactamase is achieved using methods of the invention.
    Type: Grant
    Filed: August 27, 2015
    Date of Patent: June 15, 2021
    Assignee: Synthetic Biologics, Inc.
    Inventors: Andrew Bristol, Michael Kaleko, Steven Hubert
  • Publication number: 20210030686
    Abstract: The present invention provides for a formulation comprising an active alkaline phosphatase (AP)-based agent and an enteric agent, wherein the formulation is suitable for releasing a substantial amount of the active AP-based agent in the intestines.
    Type: Application
    Filed: March 20, 2019
    Publication date: February 4, 2021
    Inventors: Andrew BRISTOL, Ray STAPLETON, Michael KALEKO, Christian FURLAN FREGUIA, Steven HUBERT, Cristina FREIRE, James GUBBINS
  • Publication number: 20210007994
    Abstract: The present invention provides, in part, formulations comprising a beta-lactamase. Particularly, modified-release formulations comprising a beta-lactamase are provided which release a substantial amount of the beta-lactamase in the intestines. Therapeutic uses of the beta-lactamase formulations are also provided.
    Type: Application
    Filed: September 28, 2020
    Publication date: January 14, 2021
    Inventors: Andrew BRISTOL, Michael KALEKO, Sheila CONNELLY
  • Patent number: 10828260
    Abstract: The present invention provides, in part, formulations comprising a beta-lactamase. Particularly, modified-release formulations comprising a beta-lactamase are provided which release a substantial amount of the beta-lactamase in the intestines. Therapeutic uses of the beta-lactamase formulations are also provided.
    Type: Grant
    Filed: August 24, 2018
    Date of Patent: November 10, 2020
    Assignee: Synthetic Biologics, Inc.
    Inventors: Andrew Bristol, Michael Kaleko, Sheila Connelly
  • Patent number: D1025985
    Type: Grant
    Filed: November 4, 2022
    Date of Patent: May 7, 2024
    Assignee: Meta Platforms Technologies, LLC
    Inventors: Joseph Patrick Sullivan, Peter Allan Chase Newbury, David Michael Pickett, Joel Bernard Jacobs, Scott Andrew Dallmeyer, Peter Wesley Bristol, Yi-yaun Chen, Mauricio Romano
  • Patent number: D1025986
    Type: Grant
    Filed: November 3, 2023
    Date of Patent: May 7, 2024
    Assignee: Meta Platforms Technologies, LLC
    Inventors: Peter Wesley Bristol, Quintin Morris, Mauricio Romano, Scott Andrew Dallmeyer, Brett Delainey Christie, Shane Michael Ellis