Abstract: A casing system includes a landing ring and a mandrel hanger. The landing ring defines an opening extending between a first end portion and a second end portion. The first end portion is configured to couple to a conductor pipe. The landing ring includes a landing ring shoulder extending radially inward from an inner surface of the opening. The mandrel hanger has an outer surface configured to engage a load ring and an engagement ring. The load ring also abuts the engagement ring and engages the landing ring shoulder.

Abstract: Access to a vehicle is controlled by detecting gestures pointing to a virtual keypad. A setup mode preconfigures a sequence of touchpoints as a security key, wherein an administrant performs a timed series of distinct gestures according to a chosen number and location of touchpoints which are detected by the vehicle using captured real-time images. Touchpoints during a plurality of repetition trials provide respective sets of datapoints for each one of the distinct gestures in the series. A respective deviation contour is determined for each respective set and then expanded to represent regions of validity for respective touchpoints corresponding to the sequence of touchpoints. The expanded deviation contours are accepted as defining the sequence of touchpoints for the security key if there is no overlap between any expanded deviation contours to complete the setup mode.

Abstract: This disclosure relates to JAK1 pathway inhibitors and their use in treating prurigo nodularis.

Abstract: One embodiment of the present invention sets forth a technique for combining a source image and a driver image. The technique includes determining a first region of the source image to be blended with the driver image. The technique also includes inputting a second region of the source image that lies outside of the first region and the driver image into a neural network. The technique further includes generating, via the neural network, an output image that includes a third region corresponding to the first region of the source image and a fourth region corresponding to the second region of the source image, where the third region includes visual attributes of the driver image and a context associated with the source image and the fourth region includes visual attributes of the second region of the source image and the context associated with the source image.

Abstract: The disclosure provides a method for vessel maintenance optimization, the method comprising the steps of: obtaining operational data of the vessel; calculating a Torque Index; calculating a Slip Index; indicating that propeller cleaning is required if the Torque Index exceeds a Torque Index threshold, and indicating that hull cleaning is required if the Slip Index exceeds a Slip Index threshold.

Abstract: A system for a well car includes a frame, a hitch coupled to the frame near the first end of the frame, and a first deck coupled to the frame. The frame includes a first pair of sockets located near a first end of the frame and a second pair of sockets located near a second end of the frame. Each socket of the first pair of sockets is configured to engage a support casting of a first pair of support castings located at a first position along a length of a well car. Each socket of the second pair of sockets is configured to engage a support casting of a second pair of support castings located at a second position along the length of the well car. The first deck is configured to hold wheels of a trailer when the trailer is coupled to the hitch.

Abstract: Aspects of the disclosure include systems and methods for planning and/or performing an ablation procedure. Volumetric image data including a needle, such as a physical ablation needle or a virtual needle, can be analyzed to segment the needle within the volume. A first cross-sectional, two-dimensional view of the volume showing a first plane in which an axis defined by the needle lies can be generated and displayed. The view can be manipulated to display a generated second cross-sectional, two-dimensional view of the volume showing a second plane through the volume in which the longitudinal axis defined by the virtual needle lies, wherein the second plane is different from the first plane. Additional segmented features such as lesions in the image data, treatment regions, isotherms, and the like can be included in views to be analyzed from a plurality of views that include the needle.

Abstract: A system and method are provided for quantifying greenhouse gas (GHG) emissions associated with vehicle traffic. The method includes receiving data from a plurality of devices located at a plurality of traffic intersections in a traffic network, each device comprising at least one sensor configured to obtain data from the corresponding traffic intersection; using the received data and a traffic model to determine vehicle trajectory data; using the vehicle trajectory data and an emissions model to obtain corresponding GHG emissions data; and evaluating the corresponding GHG emissions data to a baseline of GHG emissions using a GHG quantification methodology to determine a GHG reduction that can achieve a carbon offset credit.

Abstract: The present invention relates to compounds having activity at both the human glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors. The present invention also relates to compounds having an extended duration of action at each of these receptors. Furthermore, the present invention relates to compounds that may be administered orally. Compounds may be useful in the treatment of type 2 diabetes mellitus (“T2DM”). Also, the compounds may be useful in the treatment of obesity.

Abstract: This disclosure relates to JAK1 pathway inhibitors and their use in treating prurigo nodularis.

Abstract: A compression relief tool includes a tool body, an actuator, and a tool sleeve. The tool body is configured to couple to a wellhead. The actuator is coupled to the tool body and is configured to be coupled to the wellhead. The actuator is further configured to impart a preload force on an intermediate casing via the tool body. The tool sleeve is movable relative to the tool body. The tool sleeve is configured to engage a retaining ring coupled to the intermediate casing. The tool sleeve is movable to retrieve the retaining ring from the intermediate casing. The actuator is configured to release the preload force on the intermediate casing after the tool sleeve retrieves the retaining ring.

Abstract: The present application provides a collector terminal dust mitigation assembly for use with collector terminals of generators to prevent dust entry into a collector terminal bore in a collector ring, wherein the collector terminals may have varying positions with respect to the collector rings. The collector terminal dust mitigation assembly may include one of a number of inner elements configured for a specific position of a collector terminal with respect to a collector ring and a standard outer element sized to accommodate the inner element.

Abstract: The present invention relates to compounds having activity at both the human glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors. The present invention also relates to compounds having an extended duration of action at each of these receptors. Furthermore, the present invention relates to compounds that may be administered orally. Compounds may be useful in the treatment of type 2 diabetes mellitus (“T2DM”). Also, the compounds may be useful in the treatment of obesity.

Abstract: The present invention relates to compounds having activity at both the human glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors. The present invention also relates to compounds having an extended duration of action at each of these receptors. Furthermore, the present invention relates to compounds that may be administered orally. Compounds may be useful in the treatment of type 2 diabetes mellitus (“T2DM”). Also, the compounds may be useful in the treatment of obesity.

Abstract: A system and method are provided for quantifying greenhouse gas (GHG) emissions associated with vehicle traffic. The method includes receiving data from a plurality of devices located at a plurality of traffic intersections in a traffic network, each device comprising at least one sensor configured to obtain data from the corresponding traffic intersection; using the received data and a traffic model to determine vehicle trajectory data; using the vehicle trajectory data and an emissions model to obtain corresponding GHG emissions data; and evaluating the corresponding GHG emissions data to a baseline of GHG emissions using a GHG quantification methodology to determine a GHG reduction that can achieve a carbon offset credit.

Abstract: A system receives confirmation that a vehicle has accepted automatic control imposition for a drive within a geo-fenced boundary. The system tracks travel of a plurality of vehicles, including the vehicle, within the geo-fenced boundary. The system may determine that the vehicle has a threshold likelihood of encountering at least one of another vehicle or a boundary of the geo-fence at a threshold speed or above and responsive to the determination, impose automatic control on the vehicle, including at least one of controlled braking or speed limiting.

Abstract: An improved electromagnetic field generating antenna is compatible with fluoroscopic imaging and can be placed under, above or anywhere around the patient. The antenna includes one or more antenna elements laid out on a single or multi-layer PCB with current conducting metal traces used for creating electromagnetic fields for tracking sensors. An antenna enclosure is made with a polymer or other non-conductive material. The antenna does not have to be moved for allowing medical imaging during various procedures. An X-ray filter may be made out of similar sub-components as a full antenna assembly with the sole purpose of reducing the radiation dose to the patient during medical procedures without negatively affecting the image quality.

Abstract: An example method includes receiving, by one or more processing circuits, a registration request comprising an identifier and an activation gesture associated with a mobile application on a mobile device. The example method includes sending, by the one or more processing circuits to the mobile application on the mobile device, a notification indicating the mobile device is registered. The example method includes receiving, by the one or more processing circuits, a content item test request for content items in a specific content network. The example method includes testing, by the one or more processing circuits, the content items on the specific content network. The example method includes transmitting, by the one or more processing circuits to the mobile application on the mobile device, content event logs comprising debugging information of the content items during the testing on the content network.

Abstract: In some examples, a method of capturing a polynucleotide on a particle that includes a capture primer includes transporting the particle to a first aperture between a first fluidic compartment and a second fluidic compartment. The particle may be located in the first fluidic compartment, and the polynucleotide may be at least partially located in the second fluidic compartment. The method may include transporting the polynucleotide from the second fluidic compartment to the first fluidic compartment through the first aperture. The method may include hybridizing the polynucleotide to the capture primer.

Abstract: A system for a well car includes a frame, a hitch coupled to the frame near the first end of the frame, and a first deck coupled to the frame. The frame includes a first pair of sockets located near a first end of the frame and a second pair of sockets located near a second end of the frame. Each socket of the first pair of sockets is configured to engage a support casting of a first pair of support castings located at a first position along a length of a well car. Each socket of the second pair of sockets is configured to engage a support casting of a second pair of support castings located at a second position along the length of the well car. The first deck is configured to hold wheels of a trailer when the trailer is coupled to the hitch.