Abstract: A system and method for detecting differences in images and identifying groups of images with similar differences detected is provided. To this end, an image comparator may be operably coupled to a pixel comparator for comparing pixels of the baseline image with corresponding pixels of one or more sample images to detect differences between the pixels compared. A derivative difference processor may be also provided which may be operably coupled to the pixel comparator for determining a difference region of pixels detected as different by the pixel comparator in the sample images. An image sorter may also be provided which may be operably coupled to the difference derivative processor for grouping together sample images that have a similar difference region determined by the derivative difference processor.