Abstract: A proxy application is installed locally to an existing messaging client application. The proxy is transparent in that it requires no modification to messaging client code implementation. The proxy monitors the incoming and outgoing messaging client data, analyzes the data based on configurable criteria, and in response issues configurable control commands to a peripheral device. The peripheral device may also act as an input device: the proxy may monitor the peripheral input data, analyze the data based on configurable criteria, and in response insert new data into the messaging data stream. In addition, the proxy may monitor other information external to the messaging system, such as new email notifications, in order to trigger both device actions and messaging data stream insertions.

Abstract: A dark-sky friendly lamp-housing combination is provided for use with a light fixture. The combination uses a standard lamp having a light element and a base section. The base section includes a neck attached to the light element and a connector that is received in a socket of a light fixture. A housing attached to the neck is adapted to direct light from the light bulb in a predefined direction to reduce light pollution. In one aspect, the housing is rotatable about the base section so that the direction of illumination can be adjusted as desired.

Abstract: The invention is directed to methods of inhibiting the rate at which superoxide dismutse-1 (SOD) aggregates using compounds that stabilize SOD dimers. The methods are useful in the study and therapy of amyotrophic lateral sclerosis. The invention also includes assays that can be used to identify compounds that stabilize dimers and SOD molecules that have been modified for use in these assays.