Patents by Inventor Andrew Christopher William Zannettino

Andrew Christopher William Zannettino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multipotential Expanded Mesenchymal Precursor Cell Progeny (MEMP) and Uses Thereof
    Publication number: 20240101961
    Abstract: The invention relates to multipotential expanded mesenchymal precursor progeny (MEMP's), characterised by the early developmental markers STRO-1bri and ALP. The present invention also relates to methods for producing MEMP's and to uses of MEMP's for therapeutic applications.
    Type: Application
    Filed: November 28, 2023
    Publication date: March 28, 2024
    Applicant: Mesoblast, Inc.
    Inventors: Stan Gronthos, Andrew Christopher William Zannettino
  • Multipotential Expanded Mesenchymal Precursor Cell Progeny (MEMP) and Uses Thereof
    Publication number: 20210355447
    Abstract: The invention relates to multipotential expanded mesenchymal precursor progeny (MEMP's), characterised by the early developmental markers STRO-1bri and ALP. The present invention also relates to methods for producing MEMP's and to uses of MEMP's for therapeutic applications.
    Type: Application
    Filed: July 7, 2021
    Publication date: November 18, 2021
    Applicant: Mesoblast, Inc.
    Inventors: Stan Gronthos, Andrew Christopher William Zannettino
  • ISOLATION OF ADULT MULTIPOTENTIAL CELLS BY TISSUE NON-SPECIFIC ALKALINE PHOSPHATASE
    Publication number: 20200332023
    Abstract: The present invention relates to the use of tissue non-specific alkaline phosphatase (TNAP) as a marker for identifying and/or isolating adult multipotential cells. The present invention also relates to cell populations enriched by methods of the present invention and therapeutic uses of these cells.
    Type: Application
    Filed: May 5, 2020
    Publication date: October 22, 2020
    Applicant: Mesoblast, Inc.
    Inventors: Stan Gronthos, Andrew Christopher William Zannettino, John Paul Simmons
  • Method of increasing proliferation of bone marrow mononuclear cells expressing STRO1-
    Patent number: 10544394
    Abstract: The present invention relates to methods of enhancing proliferation and/or survival of mesenchymal precursor cells (MPC) and/or progeny derived therefrom in vitro or in vivo comprising exposing the MPC or progeny to SDF-1 or analog thereof. The invention also relates to compositions comprising isolated MPCs or progeny derived therefrom and SDF-1 or analogues thereof. The present invention also relates to using such methods and compositions for ex vivo or in vivo bone formation in mammals.
    Type: Grant
    Filed: August 27, 2014
    Date of Patent: January 28, 2020
    Assignee: Mesoblast, Inc.
    Inventors: Stan Gronthos, Andrew Christopher William Zannettino
  • Multipotential Expanded Mesenchymal Precursor Cell Progeny (MEMP) and Uses Thereof
    Publication number: 20190177685
    Abstract: The invention relates to multipotential expanded mesenchymal precursor progeny (MEMP's), characterised by the early developmental markers STRO-1bri and ALP. The present invention also relates to methods for producing MEMP's and to uses of MEMP's for therapeutic applications.
    Type: Application
    Filed: February 25, 2019
    Publication date: June 13, 2019
    Applicant: Mesoblast, Inc.
    Inventors: Stan Gronthos, Andrew Christopher William Zannettino
  • Multipotential Expanded Mesenchymal Precursor Cell Progeny (MEMP) and Uses Thereof
    Publication number: 20180237746
    Abstract: The invention relates to multipotential expanded mesenchymal precursor progeny (MEMP's), characterised by the early developmental markers STRO-1bri and ALP. The present invention also relates to methods for producing MEMP's and to uses of MEMP's for therapeutic applications.
    Type: Application
    Filed: December 19, 2017
    Publication date: August 23, 2018
    Applicant: Mesoblast, Inc.
    Inventors: Stan Gronthos, Andrew Christopher William Zannettino
  • ISOLATION OF ADULT MULTIPOTENTIAL CELLS BY TISSUE NON-SPECIFIC ALKALINE PHOSPHATASE
    Publication number: 20180009905
    Abstract: The present invention relates to the use of tissue non-specific alkaline phosphatase (TNAP) as a marker for identifying and/or isolating adult multipotential cells. The present invention also relates to cell populations enriched by methods of the present invention and therapeutic uses of these cells.
    Type: Application
    Filed: July 17, 2017
    Publication date: January 11, 2018
    Applicant: Mesoblast, Inc.
    Inventors: Stan Gronthos, Andrew Christopher William Zannettino, John Paul Simmons
  • Monoclonal antibody STRO-4
    Patent number: 9815896
    Abstract: The present invention relates to a monoclonal antibody designated STRO-4 which specifically binds human and ovine HSP-90beta and its use for enriching multipotential cells such as mesenchymal precursor cells (MPCs).
    Type: Grant
    Filed: July 9, 2015
    Date of Patent: November 14, 2017
    Assignee: ANGIOBLAST SYSTEMS, INC
    Inventors: Stan Gronthos, Andrew Christopher William Zannettino
  • Isolation of adult multipotential cells by tissue non-specific alkaline phosphatase
    Patent number: 9783617
    Abstract: The present invention relates to the use of tissue non-specific alkaline phosphatase (TNAP) as a marker for identifying and/or isolating adult multipotential cells. The present invention also relates to cell populations enriched by methods of the present invention and therapeutic uses of these cells.
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: October 10, 2017
    Assignee: ANGIOBLAST SYSTEMS, INC.
    Inventors: Stan Gronthos, Andrew Christopher William Zannettino, John Paul Simmons
  • ISOLATION OF ADULT MULTIPOTENTIAL CELLS BY TISSUE NON-SPECIFIC ALKALINE PHOSPHATASE
    Publication number: 20160264683
    Abstract: The present invention relates to the use of tissue non-specific alkaline phosphatase (TNAP) as a marker for identifying and/or isolating adult multipotential cells. The present invention also relates to cell populations enriched by methods of the present invention and therapeutic uses of these cells.
    Type: Application
    Filed: May 27, 2016
    Publication date: September 15, 2016
    Applicant: Mesoblast, Inc.
    Inventors: Stan Gronthos, Andrew Christopher William Zannettino, John Paul Simmons
  • MONOCLONAL ANTIBODY STRO-4
    Publication number: 20150307608
    Abstract: The present invention relates to a monoclonal antibody designated STRO-4 which specifically binds human and ovine HSP-90beta and its use for enriching multipotential cells such as mesenchymal precursor cells (MPCs).
    Type: Application
    Filed: July 9, 2015
    Publication date: October 29, 2015
    Applicant: MESOBLAST, INC.
    Inventors: Stan Gronthos, Andrew Christopher William Zannettino
  • ISOLATION OF ADULT MULTIPOTENTIAL CELLS BY TISSUE NON-SPECIFIC ALKALINE PHOSPHATASE
    Publication number: 20150267171
    Abstract: The present invention relates to the use of tissue non-specific alkaline phosphatase (TNAP) as a marker for identifying and/or isolating adult multipotential cells. The present invention also relates to cell populations enriched by methods of the present invention and therapeutic uses of these cells.
    Type: Application
    Filed: February 13, 2015
    Publication date: September 24, 2015
    Applicant: ANGIOBLAST SYSTEMS, INC.
    Inventors: Stan Gronthos, Andrew Christopher William Zannettino, John Paul Simmons
  • METHOD OF ENHANCING PROLIFERATION AND/OR SURVIVAL OF MESENCHYMAL PRECURSOR CELLS (MPC)
    Publication number: 20150072422
    Abstract: The present invention relates to methods of enhancing proliferation and/or survival of mesenchymal precursor cells (MPC) and/or progeny derived therefrom in vitro or in vivo comprising exposing the MPC or progeny to SDF-1 or analog thereof. The invention also relates to compositions comprising isolated MPCs or progeny derived therefrom and SDF-1 or analogues thereof. The present invention also relates to using such methods and compositions for ex vivo or in vivo bone formation in mammals.
    Type: Application
    Filed: August 27, 2014
    Publication date: March 12, 2015
    Applicant: ANGIOBLAST SYSTEMS, INC.
    Inventors: Stan Gronthos, Andrew Christopher William Zannettino
  • Multipotential Expanded Mesenchymal Precursor Cell Progeny (MEMP) and Uses Thereof
    Publication number: 20140178991
    Abstract: The invention relates to multipotential expanded mesenchymal precursor progeny (MEMP's), characterised by the early developmental markers STRO-1bri and ALP. The present invention also relates to methods for producing MEMP's and to uses of MEMP's for therapeutic applications.
    Type: Application
    Filed: June 27, 2013
    Publication date: June 26, 2014
    Applicant: MESOBLAST, INC.
    Inventors: Stan Gronthos, Andrew Christopher William Zannettino
  • Isolation of adult multipotential cells by tissue non-specific alkaline phosphatase
    Patent number: 8367405
    Abstract: The present invention relates to the use of tissue non-specific alkaline phosphatase (TNAP) as a marker for identifying and/or isolating adult multipotential cells. The present invention also relates to cell populations enriched by methods of the present invention and therapeutic uses of these cells.
    Type: Grant
    Filed: April 12, 2006
    Date of Patent: February 5, 2013
    Assignee: Mesoblast, Inc.
    Inventors: Stan Gronthos, Andrew Christopher William Zannettino, Paul John Simmons
  • Method of enhancing proliferation and/or survival of mesenchymal precursor cells (MPC)
    Publication number: 20110223668
    Abstract: The present invention relates to methods of enhancing proliferation and/or survival of mesenchymal precursor cells (MPC) and/or progeny derived therefrom in vitro or in vivo comprising exposing the MPC or progeny to SDF-1 or analog thereof. The invention also relates to compositions comprising isolated MPCs or progeny derived therefrom and SDF-1 or analogues thereof. The present invention also relates to using such methods and compositions for ex vivo or in vivo bone formation in mammals.
    Type: Application
    Filed: September 16, 2010
    Publication date: September 15, 2011
    Inventors: Stan Gronthos, Andrew Christopher William Zannettino
  • Isolation of adult multipotential cells by tissue non-specific alkaline phosphatase
    Publication number: 20090074728
    Abstract: The present invention relates to the use of tissue non-specific alkaline phosphatase (TNAP) as a marker for identifying and/or isolating adult multipotential cells. The present invention also relates to cell populations enriched by methods of the present invention and therapeutic uses of these cells.
    Type: Application
    Filed: April 12, 2006
    Publication date: March 19, 2009
    Inventors: Stan Gronthos, Andrew Christopher William Zannettino, Paul John Simmons
  • Method of enhancing proliferation and/or survival of mesenchymal precursor cells (mpc)
    Publication number: 20090029912
    Abstract: The present invention relates to methods of enhancing proliferation and/or survival of mesenchymal precursor cells (MPC) and/or progeny derived therefrom in vitro or in vivo comprising exposing the MPC or progeny to SDF-1 or analog thereof. The invention also relates to compositions comprising isolated MPCs or progeny derived therefrom and SDF-1 or analogues thereof. The present invention also relates to using such methods and compositions for ex vivo or in vivo bone formation in mammals.
    Type: Application
    Filed: June 29, 2005
    Publication date: January 29, 2009
    Inventors: Stan Gronthos, Andrew Christopher William Zannettino
  • Multipotential Expanded Mesenchymal Precursor Cell Progeny (Memp) and Uses Thereof
    Publication number: 20080260694
    Abstract: The invention relates to multipotential expanded mesenchymal precursor progeny (MEMP's), characterised by the early developmental markers STRO-1bri and ALP. The present invention also relates to methods for producing MEMP's and to uses of MEMP's for therapeutic applications.
    Type: Application
    Filed: September 26, 2005
    Publication date: October 23, 2008
    Applicant: ANGIOBLAST SYSTEMS, INC.
    Inventors: Stan Gronthos, Andrew Christopher William Zannettino