Patents by Inventor Andrew Colin Share

Andrew Colin Share has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the production of purine derivatives and intermediates therefor
    Patent number: 6806375
    Abstract: Intermediates such as methyl 2,2-dimethyl-5-ethenyl-1,3-dioxane-5-carbonate useful to prepare antiviral compounds such as penciclovir and famciclovir are disclosed.
    Type: Grant
    Filed: February 19, 2003
    Date of Patent: October 19, 2004
    Assignee: Novartis International Pharmaceutical Ltd.
    Inventors: Richard Freer, Graham Richard Geen, Thomas Weir Ramsay, Andrew Colin Share, Neil Michael Smith
  • Novel processes for the preparation of 4-phenylpiperidine derivatives
    Publication number: 20040087795
    Abstract: A process for preparing compound (E) from compound (A), with or without isolation of intermediate products, characterised by one or more of the following steps:
    Type: Application
    Filed: June 24, 2003
    Publication date: May 6, 2004
    Inventors: Gary Thomas Borrett, Michael Fedouloff, Mark Jason Hughes, Andrew Colin Share, John Bryce Strachan, Peter Szeto, Martyn Voyle
  • Process for the production of purine derivatives and intermediates therefor
    Publication number: 20030130512
    Abstract: A process for preparing purine derivatives, such as famciclovir and penciclovir, by reacting two intermediates and using a palladium(0) catalyst and a ligand. Intermediates useful in the process are also claimed.
    Type: Application
    Filed: February 19, 2003
    Publication date: July 10, 2003
    Inventors: Richard Freer, Graham Richard Geen, Thomas Weir Ramsay, Andrew Colin Share, Neil Michael Smith
  • Process for the production of purine derivatives and intermediates therefor
    Patent number: 6555685
    Abstract: A process for preparing purine derivatives, such as famiciclovir and penciclovir, by reacting, in the presence of a palladium (0) catalyst and a ligand, a compound of the formula with a compound of the formula wherein X is H, OH or halo; Y is a leaving group; and R1 and R2 are selected independently from C1-12alkyl, aryl, C1-12alkylaryl, C1-12alkylsilyl, arylsilyl and C1-12alkyldiarylsilyl or are joined together to form a moiety of the formula wherein R3 and R4 are selected independently from H, C1-12alkyl and aryl.
    Type: Grant
    Filed: November 1, 2000
    Date of Patent: April 29, 2003
    Assignee: Novartis International Pharmaceutical Ltd.
    Inventors: Richard Freer, Graham Richard Geen, Thomas Weir Ramsay, Andrew Colin Share, Neil Michael Smith
  • Process for the production of purine derivatives
    Patent number: 6437125
    Abstract: The invention provides a method of rearranging a compound of formula (I), wherein R and R′ are selected independently from hydrogen and C1-12alkyl; and R1 and R2 are selected independently from hydrogen, hydroxy, halo, C1-12alkyl- or aryl carbonate, amino, mono- or di-C1-12alkylamino, C1-12alkyl or arylamido, C1-12alkyl- or arylcarbonyl, C1-12alkyl- or arylcarboxy, C1-12alkyl- or arylcarbamoyl, C1-12alkyl, C2-12alkenyl, C2-12alkynyl, aryl, heteroaryl, C1-12alkoxy, aryloxy, azido, C1-12alkyl- or arylthio, C1-12alkyl- or arylsulfonyl, C1-12alkyl- or arylsilyl, C1-12alkyl- or arylphosphoryl, and phosphato; to form a compound of formula (II), wherein R, R′, R1 and R2 are as defined for formula (I); said method comprising treating the compound of formula (I) with a palladium (0) catalyst and a (diphenylphosphino)nC1-6 alkane, wherein n is an integer of 1-6. The invention also provides methods of R making penciclovir and famciclovir using this rearrangement reaction.
    Type: Grant
    Filed: November 1, 2000
    Date of Patent: August 20, 2002
    Assignee: Novartis International Pharmaceutical Ltd.
    Inventors: Graham Richard Geen, Andrew Colin Share