Patents by Inventor Andrew D. Badley

Andrew D. Badley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11938098
    Abstract: This document provides methods and materials involved in killing HIV infected cells (e.g., CD4 T cells). For example, methods and materials for using one or more Bcl-2 inhibitors (e.g., ABT-199) alone or in combination with one or more agents capable of reactivating HIV (e.g., latency reversing agent) to kill HIV infected cells (e.g., CD4 T cells) are provided.
    Type: Grant
    Filed: March 16, 2021
    Date of Patent: March 26, 2024
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Andrew D. Badley, Amy M. Nguyen, Scott H. Kaufmann, Yuan-Ping Pang, Haiming Dai
  • Publication number: 20230139966
    Abstract: Devices and methods are described for disinfection of pathogenic organisms using pulsed DC field electroporation. For example, this disclosure describes disinfection of pathogenic organisms using pulsed DC field electroporation for lung infection treatment, blood infection treatment, sterilization, and respirators.
    Type: Application
    Filed: April 12, 2021
    Publication date: May 4, 2023
    Inventors: Hideki Ebihara, Jason A. Tri, Kalpathi L. Venkatachalam, Paul A. Friedman, Christopher V. DeSimone, Daniel C. DeSimone, Martin van Zyl, Adetola O. Ladejobi, Andrew D. Badley, Samuel J. Asirvatham
  • Publication number: 20220127370
    Abstract: This document provides antibodies against tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) short, and more particularly to humanized TRAILshort antibodies that can neutralize TRAILshort. For example, materials and methods for using one or more humanized TRAILshort antibodies to induce apoptosis (e.g., via TRAIL mediated cell death, natural killer (NK) cytotoxicity, and/or CD8+ T cell killing) are provided.
    Type: Application
    Filed: August 24, 2021
    Publication date: April 28, 2022
    Applicant: Mayo Foundation for Medical Education and Research
    Inventor: Andrew D. Badley
  • Publication number: 20210379086
    Abstract: This document provides methods and materials involved in killing HIV infected cells (e.g., CD4 T cells). For example, methods and materials for using one or more Bcl-2 inhibitors (e.g., ABT-199) alone or in combination with one or more agents capable of reactivating HIV (e.g., latency reversing agent) to kill HIV infected cells (e.g., CD4 T cells) are provided.
    Type: Application
    Filed: March 16, 2021
    Publication date: December 9, 2021
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Andrew D. Badley, Amy M. Nguyen, Scott H. Kaufmann, Yuan-Ping Pang, Haiming Dai
  • Patent number: 11136402
    Abstract: This document provides antibodies against tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) short, and more particularly to humanized TRAILshort antibodies that can neutralize TRAILshort. For example, materials and methods for using one or more humanized TRAILshort antibodies to induce apoptosis (e.g., via TRAIL mediated cell death, natural killer (NK) cytotoxicity, and/or CD8+ T cell killing) are provided.
    Type: Grant
    Filed: February 8, 2018
    Date of Patent: October 5, 2021
    Assignee: Mayo Foundation for Medical Education and Research
    Inventor: Andrew D. Badley
  • Patent number: 10786519
    Abstract: This document provides methods and materials for treating HIV infections. For example, methods and materials for using one or more proteosome inhibitors in combination with one or more other agents to treat HIV infections are provided.
    Type: Grant
    Filed: February 19, 2016
    Date of Patent: September 29, 2020
    Assignee: Mayo Foundation for Medical Education and Research
    Inventor: Andrew D. Badley
  • Publication number: 20190367626
    Abstract: This document provides antibodies against tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) short, and more particularly to humanized TRAILshort antibodies that can neutralize TRAILshort. For example, materials and methods for using one or more humanized TRAILshort antibodies to induce apoptosis (e.g., via TRAIL mediated cell death, natural killer (NK) cytotoxicity, and/or CD8+ T cell killing) are provided.
    Type: Application
    Filed: February 8, 2018
    Publication date: December 5, 2019
    Applicant: Mayo Foundation for Medical Education and Research
    Inventor: Andrew D. Badley
  • Publication number: 20180161347
    Abstract: This document provides methods and materials involved in killing HIV infected cells (e.g., CD4 T cells). For example, methods and materials for using one or more Bcl-2 inhibitors (e.g., ABT-199) alone or in combination with one or more agents capable of reactivating HIV (e.g., latency reversing agent) to kill HIV infected cells (e.g., CD4 T cells) are provided.
    Type: Application
    Filed: April 20, 2016
    Publication date: June 14, 2018
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Andrew D. Badley, Amy M. Nguyen, Scott H. Kaufmann, Yuan-Ping Pang, Haiming Dai
  • Publication number: 20180036322
    Abstract: This document provides methods and materials for treating HIV infections. For example, methods and materials for using one or more proteosome inhibitors in combination with one or more other agents to treat HIV infections are provided.
    Type: Application
    Filed: February 19, 2016
    Publication date: February 8, 2018
    Applicant: Mayo Foundation for Medical Education and Research
    Inventor: Andrew D. Badley
  • Publication number: 20120322984
    Abstract: This document provides to methods and materials related to apoptosis. For example, methods and materials for modulating apoptosis are provided. In addition, methods and materials for treating a mammal having an apoptosis-associated condition are provided.
    Type: Application
    Filed: August 22, 2012
    Publication date: December 20, 2012
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Andrew D. Badley, Gary D. Bren, David J. Schnepple
  • Publication number: 20120035113
    Abstract: This document provides to methods and materials related to apoptosis. For example, methods and materials for modulating apoptosis are provided. In addition, methods and materials for treating a mammal having an apoptosis-associated condition are provided.
    Type: Application
    Filed: July 25, 2011
    Publication date: February 9, 2012
    Inventors: Andrew D. Badley, Gary D. Bren, David J. Schnepple
  • Patent number: 8093234
    Abstract: A method of increasing thymic output in an HIV-negative patient, comprising the steps of (a) identifying a HIV-negative patient who is in need of increased thymic output and (b) supplying an effective amount of antiretroviral agent to the patient such that the patient has an increase in naïve T-cells.
    Type: Grant
    Filed: October 13, 2006
    Date of Patent: January 10, 2012
    Assignee: Mayo Foundation For Medical Education and Research
    Inventors: Andrew D. Badley, Stacey A. R. Vlahakis
  • Patent number: 8008261
    Abstract: This document provides to methods and materials related to apoptosis. For example, methods and materials for modulating apoptosis are provided. In addition, methods and materials for treating a mammal having an apoptosis-associated condition are provided.
    Type: Grant
    Filed: August 2, 2007
    Date of Patent: August 30, 2011
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Andrew D. Badley, Gary D. Bren, David J. Schnepple
  • Publication number: 20100172914
    Abstract: This document provides to methods and materials related to apoptosis. For example, methods and materials for modulating apoptosis are provided. In addition, methods and materials for treating a mammal having an apoptosis-associated condition are provided.
    Type: Application
    Filed: August 2, 2007
    Publication date: July 8, 2010
    Inventors: Andrew D. Badley, Gary D. Bren, David J. Schnepple
  • Publication number: 20100062462
    Abstract: This document relates to methods and materials involved in detecting, monitoring, and prognosing immunodeficiency virus infections. For example, methods and materials for determining whether or not a mammal (e.g., a human) has an immunodeficiency virus infection (e.g., an HIV infection), methods and materials for determining whether or not a mammal with an immunodeficiency virus infection is improving, and methods and materials for determining whether or not a mammal with an immunodeficiency virus infection has an advanced immunodeficiency virus infection are provided.
    Type: Application
    Filed: December 14, 2006
    Publication date: March 11, 2010
    Inventors: Andrew D. Badley, Gary D. Bren, Zilin Nie