Patents by Inventor Andrew D. Levin

Andrew D. Levin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHALABLE IMATINIB FORMULATIONS, MANUFACTURE, AND USES THEREOF
    Publication number: 20240108622
    Abstract: The invention relates to inhalable imatinib formulations, manufacture, and uses thereof.
    Type: Application
    Filed: October 6, 2023
    Publication date: April 4, 2024
    Inventors: Ben Dake, Ralph Niven, Andrew D. Levin
  • COMPOSITIONS AND METHODS FOR INCREASING EFFICIENCY OF CARDIAC METABOLISM
    Publication number: 20240100173
    Abstract: Compositions and methods for increasing efficiency of cardiac metabolism are provided.
    Type: Application
    Filed: November 1, 2023
    Publication date: March 28, 2024
    Inventor: Andrew D. Levin
  • Methods and systems for characterizing nucleic acid molecules
    Patent number: 11932899
    Abstract: Provided herein are methods and systems for characterizing a nucleic acid molecule from a single cell. A method for characterizing a nucleic acid molecule from a single cell may comprise providing a partition (e.g., droplets or wells) comprising a single cell and a single bead. The single bead may comprise a nucleic acid barcode molecule. A nucleic acid molecule from the single cell and the nucleic acid barcode molecule may be used to generate a barcoded nucleic acid molecule for sequencing, which may be used to determine an epigenetic state or characteristic of the nucleic acid molecule as being associated with the single cell.
    Type: Grant
    Filed: June 6, 2019
    Date of Patent: March 19, 2024
    Assignee: 10X GENOMICS, INC.
    Inventors: Kamila Belhocine, Michael Schnall-Levin, Andrew D. Price
  • Compositions and methods for increasing efficiency of cardiac metabolism
    Patent number: 11844840
    Abstract: Compositions and methods for increasing efficiency of cardiac metabolism are provided.
    Type: Grant
    Filed: May 31, 2022
    Date of Patent: December 19, 2023
    Assignee: IMBRIA PHARMACEUTICALS, INC.
    Inventor: Andrew D. Levin
  • METHODS OF TREATING FIBROMYALGIA WITH NEUROACTIVE STEROIDS
    Publication number: 20230372365
    Abstract: The invention relates to methods of treating fibromyalgia in a human subject by providing the steroid of Formula (I):
    Type: Application
    Filed: September 30, 2021
    Publication date: November 23, 2023
    Inventors: Andrew D. Levin, Danielle Feldman
  • Inhalable imatinib formulations, manufacture, and uses thereof
    Patent number: 11806349
    Abstract: The invention relates to inhalable imatinib formulations, manufacture, and uses thereof.
    Type: Grant
    Filed: January 24, 2022
    Date of Patent: November 7, 2023
    Assignee: Aerovate Therapeutics, Inc.
    Inventors: Ben Dake, Ralph Niven, Andrew D. Levin
  • METHODS OF TREATING FEMALE HEALTH CONDITIONS RELATED TO SEX HORMONES
    Publication number: 20230210870
    Abstract: The invention provides methods of treating female health conditions related to sex hormones by providing compositions containing the steroid CV-10155.
    Type: Application
    Filed: June 7, 2021
    Publication date: July 6, 2023
    Inventors: Andrew D. Levin, Danielle Feldman
  • COMPOSITIONS THAT PREFERENTIALLY POTENTIATE SUBTYPES OF GABAA RECEPTORS AND METHODS OF USE THEREOF
    Publication number: 20230147799
    Abstract: The invention provides compositions containing isomerically pure forms of neurosteroids that permit preferential modulation of different subtypes of GABAA receptors, such as preferential modulation of ?4?3? GABAA receptors over ?1?2?2 GABAA receptors. The invention also provides methods of treating GABAA disorders using such compositions.
    Type: Application
    Filed: December 30, 2022
    Publication date: May 11, 2023
    Inventors: Andrew D. Levin, Neil Buckley
  • Compositions that preferentially potentiate subtypes of GABAreceptors and methods of use thereof
    Patent number: 11571432
    Abstract: The invention provides compositions containing isomerically pure forms of neurosteroids that permit preferential modulation of different subtypes of GABAA receptors, such as preferential modulation of ?4?3? GABAA receptors over ?1?2?2 GABAA receptors. The invention also provides methods of treating GABAA disorders using such compositions.
    Type: Grant
    Filed: March 22, 2021
    Date of Patent: February 7, 2023
    Assignee: Eliem Therapeutics (UK) Ltd
    Inventors: Andrew D. Levin, Neil Buckley
  • N-acylethanolamide derivatives and uses thereof
    Patent number: 11547681
    Abstract: The present disclosure provides certain N-Acylethanolamide derivatives, and uses relating thereto.
    Type: Grant
    Filed: December 9, 2020
    Date of Patent: January 10, 2023
    Assignee: ELIEM THERAPEUTICS, INC.
    Inventor: Andrew D. Levin
  • COMPOSITIONS AND METHODS FOR INCREASING EFFICIENCY OF CARDIAC METABOLISM
    Publication number: 20220288215
    Abstract: Compositions and methods for increasing efficiency of cardiac metabolism are provided.
    Type: Application
    Filed: May 31, 2022
    Publication date: September 15, 2022
    Inventor: Andrew D. Levin
  • METHODS OF ALTERING CARDIAC REMODELING USING COMPOUNDS THAT PROMOTE GLUCOSE OXIDATION
    Publication number: 20220249463
    Abstract: The invention provides methods for altering cardiac remodeling in a subject by providing a compound that shifts cellular metabolism from fatty acid oxidation to glucose oxidation.
    Type: Application
    Filed: May 27, 2020
    Publication date: August 11, 2022
    Inventors: Andrew D. Levin, David-Alexandre Gros, Jaikrishna Patel
  • METHODS OF TREATING FIBROSIS USING COMPOUNDS THAT PROMOTE GLUCOSE OXIDATION
    Publication number: 20220241272
    Abstract: The invention provides methods for treating or preventing fibrosis in a subject by providing a compound that shifts cellular metabolism from fatty acid oxidation to glucose oxidation.
    Type: Application
    Filed: May 27, 2020
    Publication date: August 4, 2022
    Inventors: Andrew D. Levin, David-Alexandre Gros, Jaikrishna Patel
  • COMBINATION THERAPIES THAT INCLUDE AN AGENT THAT PROMOTES GLUCOSE OXIDATION AND AN INHIBITOR OF PYRUVATE DEHYDROGENASE KINASE
    Publication number: 20220226313
    Abstract: The invention provides combination therapies that include an agent that shifts cellular metabolism from fatty acid oxidation to glucose oxidation and an inhibitor of pyruvate dehydrogenase kinase. The combination therapies are useful for treating a variety of diseases, disorders, and conditions, including diabetes, cancer, and cardiovascular conditions. The invention also provides methods of treating such conditions using the combination therapies provided herein.
    Type: Application
    Filed: May 27, 2020
    Publication date: July 21, 2022
    Inventor: Andrew D. Levin
  • INHALABLE IMATINIB FORMULATIONS, MANUFACTURE, AND USES THEREOF
    Publication number: 20220218706
    Abstract: The invention relates to inhalable imatinib formulations, manufacture, and uses thereof.
    Type: Application
    Filed: January 24, 2022
    Publication date: July 14, 2022
    Inventors: Ben Dake, Ralph Niven, Andrew D. Levin
  • Compositions and methods for increasing efficiency of cardiac metabolism
    Patent number: 11376330
    Abstract: Compositions and methods for increasing efficiency of cardiac metabolism are provided.
    Type: Grant
    Filed: October 20, 2020
    Date of Patent: July 5, 2022
    Assignee: IMBRIA PHARMACEUTICALS, INC.
    Inventor: Andrew D. Levin
  • COMBINATION THERAPIES INCLUDING INHIBITORS OF DIHYDROOROTATE DEHYDROGENASE
    Publication number: 20220202803
    Abstract: The invention provides therapeutic methods that include providing to a subject an inhibitor of dihydroorotate dehydrogenase (DHODH) and a second therapeutic agent. The methods are useful for treating cancers, such as leukemias.
    Type: Application
    Filed: April 21, 2020
    Publication date: June 30, 2022
    Inventors: Vikram S. Kumar, Andrew D. Levin, David P. Hesson
  • METHODS OF TREATING CANCER USING TRIMETAZIDINE-BASED COMPOUNDS
    Publication number: 20220168431
    Abstract: The invention provides compositions and methods for treating a subject having cancer.
    Type: Application
    Filed: March 13, 2020
    Publication date: June 2, 2022
    Inventors: Andrew D. Levin, David-Alexandre Gros, Jaikrishna Patel
  • Inhalable imatinib formulations, manufacture, and uses thereof
    Patent number: 11298355
    Abstract: The invention relates to inhalable imatinib formulations, manufacture, and uses thereof.
    Type: Grant
    Filed: May 14, 2020
    Date of Patent: April 12, 2022
    Assignee: Aerovate Therapeutics, Inc.
    Inventors: Ben Dake, Ralph Niven, Andrew D. Levin
  • Inhalable imatinib formulations, manufacture, and uses thereof
    Patent number: 11229650
    Abstract: The invention relates to inhalable imatinib formulations, manufacture, and uses thereof.
    Type: Grant
    Filed: May 14, 2020
    Date of Patent: January 25, 2022
    Assignee: Aerovate Therapeutics, Inc.
    Inventors: Ben Dake, Ralph Niven, Andrew D. Levin