Abstract: A cutter head includes a first member, a cutting bit, and a second member. The first member includes a first end and a second end and includes a first mass. The cutting bit is coupled to the first member proximate the second end. The cutting bit includes a cutting edge rotatable about the axis. The second member is rotatable about the axis and includes a second mass eccentrically positioned with respect to the axis. Rotation of the second mass causes the first member and the cutting bit to oscillate.

Abstract: Described herein are compounds that are HSD17B13 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with HSD17B13 activity.

Abstract: Described herein are compounds that are HSD17B13 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with HSD17B13 activity.

Abstract: A system for relieving pressure from within a generator casing can include a generator shaft defining a shaft channel therein and at least one rotating valve disposed within the shaft channel of the generator shaft and in fluid communication with an interior of the generator casing and the atmosphere. The rotating valve is configured to allow fluid within the generator casing to flow through the generator shaft to the atmosphere in an open state and while rotating. The rotating valve is configured to prevent fluid within the generator casing from flowing in a closed state.

Abstract: An electrical power system is disclosed for an aircraft having a hybrid-electric propulsion system, which includes a battery assembly for storing energy, an electric motor controller operatively connected to the battery assembly for conditioning and controlling power to an electric motor, and an electric motor receiving power through the motor controller for delivering torque to a shaft of the hybrid-electric propulsion system.

Abstract: A hybrid electric engine control module (ECU) can be configured to be operatively connected to a hybrid electric aircraft powerplant having a heat engine system and an electric motor system to control a torque output from each of the heat engine system and the electric motor system. The ECU can be configured to determine whether at least one of the electric motor system or the heat engine system are in a normal mode such that one of the electric motor system and/or the heat engine can provide a predetermined amount of torque. The ECU can be configured to switch to a degraded mode if either of the electric motor system or the heat engine system cannot provide the predetermined amount of torque. In the degraded mode the ECU can be configured to control the electric motor system and the heat engine system differently than in the normal mode or to not control one or both of the electric motor system or the heat engine system.

Abstract: A system for relieving pressure from within a generator casing can include a generator shaft defining a shaft channel therein and at least one rotating valve disposed within the shaft channel of the generator shaft and in fluid communication with an interior of the generator casing and the atmosphere. The rotating valve is configured to allow fluid within the generator casing to flow through the generator shaft to the atmosphere in an open state and while rotating. The rotating valve is configured to prevent fluid within the generator casing from flowing in a closed state.

Abstract: A microstrip transmission line comprising a dielectric substrate including a series of periodic sinusoidal undulation portions defining spaced apart peaks and troughs, where a distance between the peaks and troughs defines a period of the microstrip line, and where each peak defines a maximum height of the substrate and each trough defines a minimum height of the substrate. The transmission line further includes a conductive strip formed to a surface of the substrate so that the conductive strip follows the undulation portions. The conductive strip includes a modulation portion in a width direction of the conductive strip perpendicular to a signal propagation direction along the strip, where the modulation portion includes a minimum width portion provided at each peak and a maximum width portion provided at each trough so that a variation of a ratio between the width of the conductive strip and the height of the substrate is maximized.

Abstract: A passive radiometric system for thermally imaging objects in a scene. The system includes a digital square-law quantizer circuit including a plurality of comparators and a voltage divider network having a plurality of resistors. Each comparator receives a different reference signal generated by the voltage divider network and a common power signal from an antenna and outputs a high or low digital bit signal. The system also includes a delta-sigma circuit having a weighting table responsive to the digital bit signals from the comparators that converts the digital bit signals to a normalized bit word. The delta-sigma circuit also includes an accumulator that receives the digital bit words from the weighting table and provides an average of the digital bit words. The system also includes a digital-to-analog converter that converts the averaged bit words to an analog signal that is provided as a feedback signal to the quantizer circuit.

Abstract: A passive radiometric system for thermally imaging objects in a scene. The system includes a digital square-law quantizer circuit including a plurality of comparators and a voltage divider network having a plurality of resistors. Each comparator receives a different reference signal generated by the voltage divider network and a common power signal from an antenna and outputs a high or low digital bit signal. The system also includes a delta-sigma circuit having a weighting table responsive to the digital bit signals from the comparators that converts the digital bit signals to a normalized bit word. The delta-sigma circuit also includes an accumulator that receives the digital bit words from the weighting table and provides an average of the digital bit words. The system also includes a digital-to-analog converter that converts the averaged bit words to an analog signal that is provided as a feedback signal to the quantizer circuit.

Abstract: Predicting the molecular complexity of a genomic sequencing library is a critical but difficult problem in modern sequencing applications. Methods to determine how deeply to sequence to achieve complete coverage or to predict the benefits of additional sequencing are lacking. We introduce an empirical Bayesian method to accurately characterize the molecular complexity of a DNA sample for almost any sequencing application based on limited preliminary sequencing.

Abstract: This invention provides methods and arrays for determination of the methylation patterns at single-nucleotide resolution by array-based hybrid selection and next-generation sequencing of bisulfite-treated DNA.

Abstract: A rain screen system for attaching an array of panels to the outside of a building, by means of a track system. The track system includes a series of horizontal mounting tracks that extend across the entire width of the panel array. Each horizontal mounting track has an upturned building-side leg that forms both a mounting flange, through a local shim, to the building, as well as the building side of a water tight, continuous, self draining gutter system. Each track also has an upturned panel-side leg that forms both a mounting flange for the lower edge of a panel and the panel side of the gutter system. Each track also forms a water seal at the top edge of the panel. The gutter system has a weep holes on the panel side of the gutter system, adapted so that drainage is fed to the top of the lower panel.

Abstract: A tiltrotor aircraft having a wing and a rotatable pylon carried by the wing is disclosed. The pylon is secured to a pylon support spindle that extends into the wing. A link connects a radial portion of the pylon support spindle to a radial portion of an actuator spindle, such that the pylon support spindle is rotated as the actuator spindle is rotated.

Abstract: A materials handling vehicle is provided comprising a frame including a longitudinal centerline and an operator compartment; first and second front wheels coupled to the frame; a rear steer wheel assembly coupled to the frame; mast apparatus coupled to the frame and including a pair of forks; and a battery associated with the frame and having a center of gravity. The battery is preferably positioned such that the battery center of gravity is laterally offset from the longitudinal center line. A stability triangle for the vehicle is defined by a first point at the first front wheel, a second point at the second front wheel and a third point at the rear steer wheel assembly. Preferably, the stability triangle defines a scalene triangle.

Abstract: A materials handling vehicle is provided comprising a frame including structure for defining an operator compartment and structure for defining a battery compartment; first and second front wheels coupled to the frame; a rear steer wheel assembly coupled to the frame; an electric motor; and a controller coupled to a front wall of the frame to control the operation of the electric motor.

Abstract: A materials handling vehicle is provided comprising a frame including a longitudinal centerline and an operator compartment; first and second front wheels coupled to the frame; a rear steer wheel assembly coupled to the frame; mast apparatus coupled to the frame and including a pair of forks; and a battery associated with the frame and having a center of gravity. The battery is preferably positioned such that the battery center of gravity is laterally offset from the longitudinal center line. A stability triangle for the vehicle is defined by a first point at the first front wheel, a second point at the second front wheel and a third point at the rear steer wheel assembly. Preferably, the stability triangle defines a scalene triangle.

Abstract: A materials handling vehicle is provided comprising a frame including structure for defining an operator compartment and structure for defining a battery compartment; first and second front wheels coupled to the frame; a rear steer wheel assembly coupled to the frame; an electric motor; and a controller coupled to a front wall of the frame to control the operation of the electric motor.