Patents by Inventor Andrew David Abell

Andrew David Abell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Macrocyclic cysteine protease inhibitors and compositions thereof
    Patent number: 9434762
    Abstract: The present invention provides a novel class of macrocyclic compounds, which are useful as cysteine protease inhibitors. Also provided are novel intermediates and methods of preparing the compounds. The invention also provides pharmaceutical compositions comprising the compounds. The compounds and compositions are useful in methods of treating or preventing one or more diseases associated with cysteine protease activity, particularly those associated with calpain activity.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: September 6, 2016
    Assignees: UNIVERSITY OF CANTERBURY, LINCOLN UNIVERSITY, DOUGLAS PHARMACEUTICALS LIMITED
    Inventors: Andrew David Abell, James Morriss Coxon, Matthew Alan Jones, Stephen Brian McNabb, Axel Thomas Neffe, Steven Geoffrey Aitken, Blair Gibb Stuart, Janna Marie Nikkel, Joanna Kimberley Duncan, Mutita Klanchantra, James David Morton, Roy Bickerstaffe, Lucinda Jane Goodricke Robertson, Hannah Yun Young Lee, Matthew Stewart Muir
  • MACROCYCLIC COMPOUNDS AND USES THEREOF
    Publication number: 20150299250
    Abstract: The present invention relates to novel macrocyclic compounds of Formula I and their use as novel therapeutic agents for example as novel compounds used in methods of preventing and/or treating a disease, condition or state in a subject associated with dysregulation of protease activity and/or dysregulation of proteosome activity
    Type: Application
    Filed: November 15, 2013
    Publication date: October 22, 2015
    Inventors: Andrew David Abell, Krystle Chua, Markus Pietsch
  • Macrocyclic Cysteine Protease Inhibitors and Compositions Thereof
    Publication number: 20140194362
    Abstract: The present invention provides a novel class of macrocyclic compounds, which are useful as cysteine protease inhibitors. Also provided are novel intermediates and methods of preparing the compounds. The invention also provides pharmaceutical compositions comprising the compounds. The compounds and compositions are useful in methods of treating or preventing one or more diseases associated with cysteine protease activity, particularly those associated with calpain activity.
    Type: Application
    Filed: March 12, 2014
    Publication date: July 10, 2014
    Applicants: Lincoln University, Douglas Pharmaceuticals Limited, Canterprise Limited
    Inventors: Andrew David Abell, James Morriss Coxon, Matthew Alan Jones, Stephen Brian McNabb, Axel Thomas Neffe, Steven Geoffrey Aitken, Blair Gibb Stuart, Janna Marie Nikkel, Joanna Kimberley Duncan, Mutita Klanchantra, James David Morton, Roy Bickerstaffe, Lucinda Jane Goodricke Robertson, Hannah Yun Young Lee, Matthew Stewart Muir
  • Macrocyclic cysteine protease inhibitors and compositions thereof
    Patent number: 8710178
    Abstract: The present invention provides a novel class of macrocyclic compounds, which are useful as cysteine protease inhibitors. Also provided are novel intermediates and methods of preparing the compounds. The invention also provides pharmaceutical compositions comprising the compounds. The compounds and compositions are useful in methods of treating or preventing one or more diseases associated with cysteine protease activity, particularly those associated with calpain activity.
    Type: Grant
    Filed: October 18, 2007
    Date of Patent: April 29, 2014
    Assignees: Lincoln University, Canterprise Limited, Douglas Pharmaceuticals Limited
    Inventors: Andrew David Abell, James Morriss Coxon, Matthew Alan Jones, Stephen Brian McNabb, Axel Thomas Neffe, Steven Geoffrey Aitken, Blair Gibb Stuart, Janna Marie Nikkel, Joanna Kimberley Duncan, Mutita Klanchantra, James David Morton, Roy Bickerstaffe, Lucinda Jane Goodricke Robertson, Hannah Yun Young Lee, Matthew Stewart Muir
  • Macrocyclic Cysteine Protease Inhibitors and Compositions Thereof
    Publication number: 20110021434
    Abstract: The present invention provides a novel class of macrocyclic compounds, which are useful as cysteine protease inhibitors. Also provided are novel intermediates and methods of preparing the compounds. The invention also provides pharmaceutical compositions comprising the compounds. The compounds and compositions are useful in methods of treating or preventing one or more diseases associated with cysteine protease activity, particularly those associated with calpain activity.
    Type: Application
    Filed: October 18, 2007
    Publication date: January 27, 2011
    Inventors: Andrew David Abell, James Morriss Coxon, Matthew Alan Jones, Stephen Brian McNabb, Axel Thomas Neffe, Steven Geoffrey Aitken, Blair Gibb Stuart, Janna Marie Nikkel, Joanna Kimberley Duncan, Mutita Klanchantra, James David Morton, Roy Bickerstaffe, Lucinda Jane Goodricke Robertson, Hannah Yun Young Lee, Matthew Stewart Muir