Patents by Inventor Andrew David Bruce Pannifer

Andrew David Bruce Pannifer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystal structure of aurora a kinase and uses thereof
    Patent number: 7214518
    Abstract: The invention provides crystalline forms of a polypeptide corresponding to the catalytic domain of Aurora kinase. The active site ATP binding pocket is defined by its amino acid residues and their atomic coordinates. This structure may be used to select or design chemical modulators of Aurora kinase, particularly Aurora inhibitors. These modulators may be used to treat diseases of cell proliferation, e.g. cancer.
    Type: Grant
    Filed: October 8, 2002
    Date of Patent: May 8, 2007
    Assignee: AstraZeneca AB
    Inventors: Malcom Anderson, Nicholas John Keen, Andrew David Bruce Pannifer, Richard Alexander Pauptit, Sian Rowsell