Patents by Inventor Andrew David Carlson

Andrew David Carlson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Activated protein C formulations
    Publication number: 20040028670
    Abstract: The present invention relates to pharmaceutical formulations of activated protein C. The activated protein C formulations of the present invention are more stable than other formulations of activated protein C and demonstrate fewer degradation products over time.
    Type: Application
    Filed: August 6, 2003
    Publication date: February 12, 2004
    Inventors: Andrew David Carlson, Theodore Arsay Sheliga
  • Activated protein C formulations
    Patent number: 6630137
    Abstract: The present invention relates to pharmaceutical formulations of activated protein C. The activated protein C formulations of the present invention are more stable than other formulations of activated protein C and demonstrate fewer degradation products over time.
    Type: Grant
    Filed: April 6, 2000
    Date of Patent: October 7, 2003
    Assignee: Eli Lilly and Company
    Inventors: Andrew David Carlson, Theodore Arsay Sheliga
  • Activated protein C formulations
    Patent number: 6436397
    Abstract: The present invention is broadly directed to a method for reducing autodegradation of activated protein C during processing and purification. The present invention provides aqueous activated protein C solutions and an improved method of processing of such solutions, comprising conducting such processing at an ionic strength of greater than 150 mM and at a pH of about 5.5 to less than 6.3.
    Type: Grant
    Filed: September 21, 2000
    Date of Patent: August 20, 2002
    Assignee: Eli Lilly and Company
    Inventors: Jeffrey Clayton Baker, Andrew David Carlson, Lihua Huang, Theodore Arsay Sheliga
  • Activated protein C formulations
    Patent number: 6395270
    Abstract: The present invention relates to pharmaceutical formulations of activated protein C which also comprises sucrose, sodium chloride and sodium citrate buffer at a pH between about 5.5 and about 6.5. The activated protein C formulations of the present invention are more stable than other formulations of activated protein C and demonstrate fewer degradation products over time.
    Type: Grant
    Filed: September 14, 2000
    Date of Patent: May 28, 2002
    Assignee: Eli Lilly and Company
    Inventors: Andrew David Carlson, Theodore Arsay Sheliga
  • Methods for processing activated protein C
    Patent number: 6162629
    Abstract: The present invention is broadly directed to a method for reducing autodegradation of activated protein C during processing and purification. The present invention provides aqueous activated protein C solutions and an improved method of processing of such solutions, comprising conducting such processing at an ionic strength of greater than 150 mM and at a pH of about 5.5 to less than 6.3.
    Type: Grant
    Filed: April 24, 1998
    Date of Patent: December 19, 2000
    Assignee: Eli Lilly And Company
    Inventors: Jeffrey Clayton Baker, Andrew David Carlson, Lihua Huang, Theodore Arsay Sheliga
  • Activated protein C formulations
    Patent number: 6159468
    Abstract: The present invention relates to pharmaceutical formulations of activated protein C which also comprises sucrose, sodium chloride and sodium citrate buffer at a pH between about 5.5 and about 6.5. The activated protein C formulations of the present invention are more stable than other formulations of activated protein C and demonstrate fewer degradation products over time.
    Type: Grant
    Filed: April 24, 1998
    Date of Patent: December 12, 2000
    Assignee: Eli Lilly and Company
    Inventors: Andrew David Carlson, Theodore Arsay Sheliga