Patents by Inventor Andrew David Pannifer

Andrew David Pannifer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystal structure of enzyme and uses thereof
    Publication number: 20060078975
    Abstract: The invention provides crystalline forms of a polypeptide corresponding to the catalytic domain of Aurora kinase. The active site ATP binding pocket is defined by its amino acid residues and their atomic coordinates. This structure may be used to select or design chemical modulators of Aurora kinase, particularly Aurora inhibitors. These modulators may be used to treat diseases of cell proliferation, e.g. cancer.
    Type: Application
    Filed: October 8, 2002
    Publication date: April 13, 2006
    Applicant: AstraZeneca AB
    Inventors: Malcom Anderson, Nicholas Keen, Andrew David Pannifer, Richard Pauptit, Sian Rowsell