Patents by Inventor Andrew Dixon Skora

Andrew Dixon Skora has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-IL-1-BETA ANTIBODIES
    Publication number: 20250042990
    Abstract: The present invention provides engineered human interleukin-1 beta antibodies, cells and vectors comprising DNA encoding the same, and methods for producing the antibodies. In addition, the present invention provides the use of the human engineered interleukin-1-beta antibodies for the treatment of inflammatory disease, such as cardiovascular disease and cancer.
    Type: Application
    Filed: September 12, 2022
    Publication date: February 6, 2025
    Inventors: Supratik DUTTA, Juqun SHEN, Andrew Dixon SKORA, Cheng WANG
  • BISPECIFIC ANTI-FLT3/CD3 ANTIBODIES AND METHODS OF USE
    Publication number: 20240368288
    Abstract: Provided herein are bispecific anti-FLT3/CD3 antibodies and antigen binding fragments thereof, such as the antibodies and fragments that specifically bind human FLT3 and human CD3. In some aspects, provided herein are optimized humanized, bispecific anti-FLT3/CD3 antibodies and antigen binding fragments thereof, optionally, having certain amino acid substitutions that confer advantageous properties (e.g., optimal antigen binding, manufacturability and/or half-life properties). Also provided herein are pharmaceutical compositions comprising such antibodies or fragments. Also provided herein are methods of use of such antibodies and fragments.
    Type: Application
    Filed: August 15, 2022
    Publication date: November 7, 2024
    Inventors: Vladislav M. SANDLER, Elina SHRESTHA, Carina Rachel SIROCHINSKY, Raymond LIANG, Ronen BEN JEHUDA, Andrew Ihor KORYTKO, Andrew Dixon SKORA, Max Ephraim ADER, Todd Christopher CHILTON
  • COMPOUNDS AND METHODS TARGETING INTERLEUKIN-34
    Publication number: 20240309082
    Abstract: The present disclosure relates to IL-34 antibodies, compositions comprising the same, and methods of using the antibodies and or compositions thereof for treating immune-mediated diseases such as neurodegenerative diseases, for example Alzheimer's Disease or a tauopathy disease.
    Type: Application
    Filed: April 5, 2024
    Publication date: September 19, 2024
    Inventors: Marcio CHEDID, Adam S. FLEISHER, Megan Brittany LANNAN, Albert LO, Mark MINTUN, Victor H. OBUNGU, Sarah Elisabeth RAINES, John Randall SIMS, II, Andrew Dixon SKORA, Robin Elizabeth WALSH, Elizabeth Anne WEST, Ming YE
  • Compounds and methods targeting interleukin-34
    Patent number: 11976114
    Abstract: The present disclosure relates to IL-34 antibodies, compositions comprising the same, and methods of using the antibodies and or compositions thereof for treating immune-mediated diseases such as neurodegenerative diseases, for example Alzheimer's Disease or a tauopathy disease.
    Type: Grant
    Filed: October 27, 2022
    Date of Patent: May 7, 2024
    Assignee: ELI Lilly and Company
    Inventors: Marcio Chedid, Adam S. Fleisher, Megan Brittany Lannan, Albert Lo, Mark Mintun, Victor H. Obungu, Sarah Elisabeth Raines, John Randall Sims, II, Andrew Dixon Skora, Robin Elizabeth Walsh, Elizabeth Anne West, Ming Ye
  • COMPOUNDS AND METHODS TARGETING INTERLEUKIN-34
    Publication number: 20240141033
    Abstract: The present invention relates to IL-34 antibodies, compositions comprising the same, and methods of using the antibodies and or compositions thereof for treating immune-mediated diseases such as neurodegenerative diseases, for example Alzheimer's Disease or a tauopathy disease.
    Type: Application
    Filed: April 7, 2023
    Publication date: May 2, 2024
    Inventors: Marcio Chedid, Victor H. Obungu, Andrew Dixon Skora, Ming Ye
  • COMPOUNDS AND METHODS TARGETING INTERLEUKIN-34
    Publication number: 20230279098
    Abstract: The present invention relates to IL-34 antibodies, compositions comprising the same, and methods of using the antibodies and or compositions thereof for treating immune-mediated diseases such as neurodegenerative diseases, for example Alzheimer's Disease or a tauopathy disease.
    Type: Application
    Filed: April 7, 2023
    Publication date: September 7, 2023
    Inventors: Marcio Chedid, Victor H. Obungu, Andrew Dixon Skora, Ming Ye
  • COMPOUNDS AND METHODS TARGETING INTERLEUKIN-34
    Publication number: 20230279094
    Abstract: The present disclosure relates to IL-34 antibodies, compositions comprising the same, and methods of using the antibodies and or compositions thereof for treating immune-mediated diseases such as neurodegenerative diseases, for example Alzheimer’s Disease or a tauopathy disease.
    Type: Application
    Filed: October 27, 2022
    Publication date: September 7, 2023
    Inventors: Marcio Chedid, Adam S. Fleisher, Megan Brittany Lannan, Albert Lo, Mark Mintun, Victor H. Obungu, Sarah Elisabeth Raines, John Randall Sims, II, Andrew Dixon Skora, Robin Elizabeth Walsh, Elizabeth Anne West, Ming Ye
  • Antibodies to IL-34
    Patent number: 11649280
    Abstract: The present invention relates to IL-34 antibodies, compositions comprising the same, and methods of using the antibodies and or compositions thereof for treating immune-mediated diseases such as neurodegenerative diseases, for example Alzheimer's Disease or a tauopathy disease.
    Type: Grant
    Filed: April 23, 2021
    Date of Patent: May 16, 2023
    Assignee: Eli Lilly and Company
    Inventors: Marcio Chedid, Victor H. Obungu, Andrew Dixon Skora, Ming Ye
  • ANTI-IL-1-BETA ANTIBODIES
    Publication number: 20230057665
    Abstract: The present disclosure provides human engineered IL-1 beta antibodies, cells and vectors comprising DNA encoding the same, and methods for producing the antibodies. In addition, the present disclosure provides the use of the human engineered IL-1 beta antibodies for the treatment of inflammatory diseases such as cardiovascular disease and cancer.
    Type: Application
    Filed: January 19, 2021
    Publication date: February 23, 2023
    Inventors: Wendy Loza HOBBS, Andrew Dixon SKORA
  • COMPOUNDS AND METHODS TARGETING INTERLEUKIN-34
    Publication number: 20210363232
    Abstract: The present invention relates to IL-34 antibodies, compositions comprising the same, and methods of using the antibodies and or compositions thereof for treating immune-mediated diseases such as neurodegenerative diseases, for example Alzheimer's Disease or a tauopathy disease.
    Type: Application
    Filed: April 23, 2021
    Publication date: November 25, 2021
    Inventors: Marcio Chedid, Victor H. Obungu, Andrew Dixon Skora, Ming Ye