Patents by Inventor Andrew E. Brereton

Andrew E. Brereton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD AND SYSTEM FOR PREDICTING DRUG BINDING USING SYNTHETIC DATA
    Publication number: 20220108766
    Abstract: A method for predicting drug-target binding using synthetically-augmented data involves generating a multitude of ghost ligands for a multitude of proteins in a protein structure database, generating a multitude of drug-target interaction (DTI) features for proteins and ligands in a DTI database, using the multitude of ghost ligands, generating a machine learning model using the multitude of DTI features, and predicting a likelihood of interaction for a combination of a query protein and a query ligand using the machine learning model.
    Type: Application
    Filed: January 2, 2020
    Publication date: April 7, 2022
    Applicant: CYCLICA INC.
    Inventors: Stephen Scott Mackinnon, Zhaleh Safikhani, Robert Vernon, Andrew E. Brereton, Andreas Windemuth