Patents by Inventor Andrew F Wilks

Andrew F Wilks has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical compositions comprising a VEGF-D polypeptide
    Patent number: 8759286
    Abstract: Described herein are pharmaceutical compositions comprising a VEGF-D polypeptide.
    Type: Grant
    Filed: April 19, 2013
    Date of Patent: June 24, 2014
    Assignee: Vegenics Pty Limited
    Inventors: Marc G. Achen, Stephen A. Stacker, Kari Alitalo, Andrew F. Wilks
  • Methods of making VEGF-D polypeptides
    Patent number: 8445234
    Abstract: Disclosed herein are methods of making a VEGF-D polypeptide comprising the steps of culturing a host cell transformed or transfected with a vector comprising a nucleic acid sequence encoding the VEGF-D polypeptide operably associated with a promoter sequence such that the nucleic acid sequence encoding the VEGF-D polypeptide is expressed; and isolating the VEGF-D polypeptide from the host cell or from the growth medium in which said host cell is cultured.
    Type: Grant
    Filed: May 17, 2012
    Date of Patent: May 21, 2013
    Assignee: Vengenics Pty Limited
    Inventors: Marc G. Achen, Stephen A. Stacker, Kari Alitalo, Andrew F. Wilks
  • GROWTH FACTOR
    Publication number: 20120322105
    Abstract: VEGF-D, new member of the PDGF family of growth factors, which among other things stimulates endothelial cell proliferation and angiogenesis and increases vascular permeability, as well as nucleotide sequences encoding it, methods for producing it, antibodies and other antagonists to it, transfected or transformed host cells for expressing it, pharmaceutical compositions containing it, and uses thereof in medical and diagnostic applications.
    Type: Application
    Filed: May 17, 2012
    Publication date: December 20, 2012
    Applicant: Vegenics PTY Limited
    Inventors: Marc G. Achen, Andrew F. Wilks, Steven A. Stacker, Kari Alitalo
  • Methods of stimulating wound healing by administration of vascular endothelial growth factor D (VEGF-D)
    Patent number: 8227410
    Abstract: VEGF-D, a new member of the PDGF family of growth factors, which among other things stimulates endothelial cell proliferation and angiogenesis and increases vascular permeability, as well as nucleotide sequences encoding it, methods for producing it, antibodies and other antagonists to it, transfected or transformed host cells for expressing it, pharmaceutical compositions containing it, and uses thereof in medical and diagnostic applications.
    Type: Grant
    Filed: March 16, 2011
    Date of Patent: July 24, 2012
    Assignee: Vegenics Pty Limited
    Inventors: Marc G. Achen, Andrew F. Wilks, Steven A. Stacker, Kari Alitalo
  • Vascular Endothelial Growth Factor D (VEGF-D) Antibodies and Vectors, and Methods of Uses
    Publication number: 20110281799
    Abstract: VEGF-D, a new member of the PDGF family of growth factors, which among other things stimulates endothelial cell proliferation and angiogenesis and increases vascular permeability, as well as nucleotide sequences encoding it, methods for producing it, antibodies and other antagonists to it, transfected or transformed host cells for expressing it, pharmaceutical compositions containing it, and uses thereof in medical and diagnostic applications.
    Type: Application
    Filed: March 16, 2011
    Publication date: November 17, 2011
    Inventors: Marc G. Achen, Andrew F. Wilks, Steven A. Stacker, Kari Alitalo
  • Methods of using VEGF-D polypeptides
    Patent number: 7928061
    Abstract: Disclosed herein are various uses for VEGF-D polypeptides. Exemplary uses include methods of stimulating endothelial cell proliferation, methods of stimulating vascular permeability, methods of stimulating angiogenesis and methods of activating VEGFR-2 and VEGFR-3 using VEGF-D polypeptides.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: April 19, 2011
    Assignee: Vegenics Pty Limited
    Inventors: Marc G. Achen, Steven Stacker, Kari Alitalo, Andrew F. Wilks
  • Mammalian cells that express VEGF-D polypeptides
    Patent number: 7871798
    Abstract: Disclosed herein are mammalian cells transformed or transfected with a VEGF-D nucleic acid consisting of a nucleotide sequence encoding continuous portions of VEGF-D polypeptides.
    Type: Grant
    Filed: August 23, 2007
    Date of Patent: January 18, 2011
    Assignee: Vegenics Limited
    Inventors: Marc G. Achen, Andrew F. Wilks, Steven Stacker, Kari Alitalo
  • Antibody diagnostic kits and methods of use
    Patent number: 7785803
    Abstract: Disclosed herein are VEGF-D antibody diagnostic kits and methods of using such kits for the detection of VEGF-D in a biological sample.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: August 31, 2010
    Assignee: Vegenics Limited
    Inventors: Marc G. Achen, Steven A. Stacker, Kari Alitalo, Andrew F. Wilks
  • Vascular endothelial growth factor D (VEGF-D) polypeptides and methods of use
    Patent number: 7662932
    Abstract: The present invention provides VEGF-D polypeptides, which among other things stimulate endothelial cell proliferation and angiogenesis and increases vascular permeability, as well as fragments, dimers, and methods of using the same.
    Type: Grant
    Filed: June 29, 2007
    Date of Patent: February 16, 2010
    Assignee: Vegenics Limited
    Inventors: Marc G. Achen, Andrew F. Wilks, Stephen A. Stacker, Kari Alitalo
  • VEGF-D polynucleotides and methods of use
    Publication number: 20090087905
    Abstract: VEGF-D, a new member of the PDGF family of growth factors, which among other things stimulates endothelial cell proliferation and angiogenesis and increases vascular permeability, as well as nucleotide sequences encoding it, methods for producing it, antibodies and other antagonists to it, transfected or transformed host cells for expressing it, pharmaceutical compositions containing it, and uses thereof in medical and diagnostic applications.
    Type: Application
    Filed: October 30, 2007
    Publication date: April 2, 2009
    Applicant: VEGENICS LIMITED
    Inventors: Marc G. Achen, Andrew F. Wilks, Steven A. Stacker, Kari Alitalo
  • Vascular endothelial growth factor D(VEGF-D) antibodies and methods of use
    Patent number: 7410639
    Abstract: VEGF-D, a new member of the PDGF family of growth factors, which among other things stimulates endothelial cell proliferation and angiogenesis and increases vascular permeability, as well as nucleotide sequences encoding it, methods for producing it, antibodies and other antagonists to it, transfected or transformed host cells for expressing it, pharmaceutical compositions containing it, and uses thereof in medical and diagnostic applications.
    Type: Grant
    Filed: June 5, 2002
    Date of Patent: August 12, 2008
    Assignee: Vegenics Limited
    Inventors: Marc G. Achen, Andrew F. Wilks, Steven A. Stacker, Kari Alitalo
  • Vascular endothelial growth factor D (VEGF-D) antibodies and vectors, and methods of use
    Publication number: 20080145366
    Abstract: VEGF-D, a new member of the PDGF family of growth factors, which among other things stimulates endothelial cell proliferation and angiogenesis and increases vascular permeability, as well as nucleotide sequences encoding it, methods for producing it, antibodies and other antagonists to it, transfected or transformed host cells for expressing it, pharmaceutical compositions containing it, and uses thereof in medical and diagnostic applications.
    Type: Application
    Filed: March 28, 2007
    Publication date: June 19, 2008
    Applicants: Licentia, Ltd.
    Inventors: Marc G. Achen, Andrew F. Wilks, Steven A. Stacker, Kari Alitalo
  • Vascular endothelial growth factor D (VEGF-D) antibodies and vectors, and methods of use
    Patent number: 7122654
    Abstract: VEGF-D, a new member of the PDGF family of growth factors, which among other things stimulates endothelial cell proliferation and angiogenesis and increases vascular permeability, as well as nucleotide sequences encoding it, methods for producing it, antibodies and other antagonists to it, transfected or transformed host cells for expressing it, pharmaceutical compositions containing it, and uses thereof in medical and diagnostic applications.
    Type: Grant
    Filed: October 22, 2002
    Date of Patent: October 17, 2006
    Assignees: Ludwig Institute for Cancer Research, Helsinki University Licensing Ltd.
    Inventors: Marc G. Achen, Andrew F. Wilks, Steven Stacker, Kari Alitalo
  • Vascular endothelial growth factor D(VEGF-D) antibodies and vectors, and methods of use
    Publication number: 20040175730
    Abstract: VEGF-D, a new member of the PDGF family of growth factors, which among other things stimulates endothelial cell proliferation and angiogenesis and increases vascular permeability, as well as nucleotide sequences encoding it, methods for producing it, antibodies and other antagonists to it, transfected or transformed host cells for expressing it, pharmaceutical compositions containing it, and uses thereof in medical and diagnostic applications.
    Type: Application
    Filed: November 12, 2003
    Publication date: September 9, 2004
    Applicants: Ludwig Institute for Cancer Research, Helsinki University Licensing Ltd., OY
    Inventors: Marc G. Achen, Andrew F. Wilks, Steven A. Stacker, Kari Alitalo
  • Growth factor
    Patent number: 6689580
    Abstract: VEGF-D, a new member of the PDGF family of growth factors, which among other things stimulates endothelial cell proliferation and angiogenesis and increases vascular permeability, as well as nucleotide sequences encoding it, methods for producing it, antibodies and other antagonists to it, transfected or transformed host cells for expressing it, pharmaceutical compositions containing it, and uses thereof in medical and diagnostic applications.
    Type: Grant
    Filed: April 22, 1999
    Date of Patent: February 10, 2004
    Assignees: Ludwig Institute for Cancer Research, Helsinki University Licensing Ltd.
    Inventors: Marc G. Achen, Andrew F. Wilks, Steven A. Stacker, Kari Alitalo
  • Vascular endothelial growth factor D(VEGF-D) antibodies and vectors, and methods of use
    Publication number: 20030125537
    Abstract: VEGF-D, a new member of the PDGF family of growth factors, which among other things stimulates endothelial cell proliferation and angiogenesis and increases vascular permeability, as well as nucleotide sequences encoding it, methods for producing it, antibodies and other antagonists to it, transfected or transformed host cells for expressing it, pharmaceutical compositions containing it, and uses thereof in medical and diagnostic applications.
    Type: Application
    Filed: June 5, 2002
    Publication date: July 3, 2003
    Applicant: Ludwig Institute for Cancer Research and Helsinki University Licensing Ltd. OY
    Inventors: Marc G. Achen, Andrew F. Wilks, Steven A. Stacker, Kari Alitalo
  • Vascular endothelial growth factor D (VEGF-D) antibodies and vectors, and methods of use
    Publication number: 20030114658
    Abstract: VEGF-D, a new member of the PDGF family of growth factors, which among other things stimulates endothelial cell proliferation and angiogenesis and increases vascular permeability, as well as nucleotide sequences encoding it, methods for producing it, antibodies and other antagonists to it, transfected or transformed host cells for expressing it, pharmaceutical compositions containing it, and uses thereof in medical and diagnostic applications.
    Type: Application
    Filed: October 22, 2002
    Publication date: June 19, 2003
    Applicant: Ludwig Institute for Cancer Research
    Inventors: Marc G. Achen, Andrew F. Wilks, Steven A. Stacker, Kari Alitalo
  • Vascular endothelial growth factor-D (VEGF-D) polypeptides
    Patent number: 6235713
    Abstract: VEGF-D, a new member of the PDGF family of growth factors, which among other things stimulates endothelial cell proliferation and angiogenesis and increases vascular permeability, as well as nucleotide sequences encoding it, methods for producing it, antibodies and other antagonists to it, transfected or transformed host cells for expressing it, pharmaceutical compositions containing it, and uses thereof in medical and diagnostic applications.
    Type: Grant
    Filed: August 21, 1997
    Date of Patent: May 22, 2001
    Assignees: Ludwig Institute for Cancer Research, Helsinki University Licensing Ltd.
    Inventors: Marc G. Achen, Andrew F. Wilks, Steven A. Stacker, Kari Alitalo
  • Antibodies specific for the extracellular domain of NYK/flk-1 protein and uses thereof
    Patent number: 6218516
    Abstract: The present invention relates to immunointeractive molecules and their use in therapeutics and diagnostics. More particularly, the present invention provides antibodies that bind to NYK/flk-1 receptors, in particular the extracellular domain.
    Type: Grant
    Filed: September 30, 1996
    Date of Patent: April 17, 2001
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Andrew F Wilks, Steven A Stacker, Robert B Oelrichs
  • Receptor-type tyrosine kinase-like molecules
    Patent number: 6107472
    Abstract: The present invention relates to proteins having receptor-type tyrosine kinase-like properties which represent a novel family of proteins related to protein tyrosine kinases. The present invention relates to the full length proteins and to subunits, mutants, derivatives and/or analogues thereof and to nucleotide sequences encoding same. The present invention also extends to ligands for the above proteins and to pharmaceutical compositions comprising the proteins and/or mutants, derivatives and/or analogues thereof and/or ligands thereto.
    Type: Grant
    Filed: January 19, 1995
    Date of Patent: August 22, 2000
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Steven A. Stacker, Christopher M. Hovens, Andrew F. Wilks