Patents by Inventor Andrew FLEISCHMAN

Andrew FLEISCHMAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MULTIPLEX ASSAY READER AND MICROFLUIDIC TEST CARTRIDGE
    Publication number: 20250025877
    Abstract: A card reading system in which electrical contacts between the assay card and the card reader are made through vertical actuation of a card interface relative to the assay card. In one embodiment, the assay card reading system comprises: (a) a card reader comprising at least one card interface, the card interface having a plurality of card interface contacts; (b) an assay card having card contacts; (c) a vertical actuation mechanism for causing relative vertical movement between the assay card and the card interface to contact at least a portion of the card interface contacts with the card contacts.
    Type: Application
    Filed: September 10, 2024
    Publication date: January 23, 2025
    Inventors: Andrew FLEISCHMAN, Kamyar GHOFRANI,, Bayan MASHREQUI
  • BENZALDEHYDE COMPOUNDS WITH DIRECT POLYMER DESTABILIZING EFFECTS TO TREAT SICKLE CELL DISEASE
    Publication number: 20250019349
    Abstract: Compounds and methods for preventing and/or treating one or more symptoms of sickle cell diseases (SCD) by administering at least one of the compounds are provided. The compounds are chemically modified to increase bioavailability and activity, e.g., so that the compounds prevent adhesion and sickling of red blood cells (RBCs).
    Type: Application
    Filed: July 9, 2024
    Publication date: January 16, 2025
    Inventors: Martin SAFO, Yan ZHANG, Andrew FLEISCHMAN, David LIGHT, Moustafa EL-ARABY, Abdelsattar OMAR, Osheiza ABDULMALIK
  • Benzaldehyde compounds with direct polymer destabilizing effects to treat sickle cell disease
    Patent number: 12065408
    Abstract: Compounds and methods for preventing and/or treating one or more symptoms of sickle cell diseases (SCD) by administering at least one of the compounds are provided. The compounds are chemically modified to increase bioavailability and activity, e.g., so that the compounds prevent adhesion and sickling of red blood cells (RBCs).
    Type: Grant
    Filed: November 3, 2023
    Date of Patent: August 20, 2024
    Assignees: VIRGINIA COMMONWEALTH UNIVERISTY, KING ABDULAZIZ UNIVERSITY, CHILDREN'S HOSPITAL OF PHILADELPHIA (CHOP), ILLEXCOR HOLDINGS, LLC
    Inventors: Martin Safo, Yan Zhang, Andrew Fleischman, David Light, Moustafa El-Araby, Abdelsattar Omar, Osheiza Abdulmalik
  • BENZALDEHYDE COMPOUNDS WITH DIRECT POLYMER DESTABILIZING EFFECTS TO TREAT SICKLE CELL DISEASE
    Publication number: 20240174612
    Abstract: Compounds and methods for preventing and/or treating one or more symptoms of sickle cell diseases (SCD) by administering at least one of the compounds are provided. The compounds are chemically modified to increase bioavailability and activity, e.g., so that the compounds prevent adhesion and sickling of red blood cells (RBCs).
    Type: Application
    Filed: November 3, 2023
    Publication date: May 30, 2024
    Inventors: Martin SAFO, Yan ZHANG, Andrew FLEISCHMAN, David LIGHT, Moustafa EL-ARABY, Abdelsattar OMAR, Osheiza ABDULMALIK
  • BENZALDEHYDE COMPOUNDS WITH DIRECT POLYMER DESTABILIZING EFFECTS TO TREAT SICKLE CELL DISEASE
    Publication number: 20240109843
    Abstract: Compounds and methods for preventing and/or treating one or more symptoms of sickle cell diseases (SCD) by administering at least one of the compounds are provided. The compounds are chemically modified to increase bioavailability and activity, e.g., so that the compounds prevent adhesion and sickling of red blood cells (RBCs).
    Type: Application
    Filed: November 3, 2023
    Publication date: April 4, 2024
    Inventors: Martin SAFO, Yan ZHANG, Piyusha Pradeep PAGARE, Guoyan XU, Mohini GHATGE, Jurgen VENITZ, Osheiza ABDULMALIK, Andrew FLEISCHMAN, David LIGHT, Moustafa EL-ARABY, Abdelsattar OMAR
  • Redox substrates for leukocyte esterase
    Patent number: 11492331
    Abstract: Certain embodiments are directed hydrophilic redox substrates for leukocyte esterase (LE). In certain aspects a hydrophilic redox leukocyte esterase substrate or a small molecule enzyme substrate for use in methods and/or devices to electrochemically detect and/or measure LE activity in a sample.
    Type: Grant
    Filed: November 8, 2018
    Date of Patent: November 8, 2022
    Assignee: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Waldemar Gorski, Stanton McHardy, Douglas Hanson, Travis Menard, Andrew Fleischman
  • REDOX SUBSTRATES FOR LEUKOCYTE ESTERASE
    Publication number: 20210171467
    Abstract: Certain embodiments are directed hydrophilic redox substrates for leukocyte esterase (LE). In certain aspects a hydrophilic redox leukocyte esterase substrate or a small molecule enzyme substrate for use in methods and/or devices to electrochemically detect and/or measure LE activity in a sample.
    Type: Application
    Filed: November 8, 2018
    Publication date: June 10, 2021
    Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Waldemar GORSKI, Stanton MCHARDY, Douglas HANSON, Travis MENARD, Andrew FLEISCHMAN