Abstract: Substituted cyclohexyl chemical entities of Formula (I): wherein Ra, G, and Rb have any of the values described herein, and compositions comprising such chemical entities; methods of making them; and their use in a wide range of methods, including metabolic and reaction kinetic studies; detection and imaging techniques; radioactive therapies; modulating and treating disorders mediated by nociceptin activity or dopamine signaling; treating neurological disorders, neurodegenerative diseases, depression, and schizophrenia; enhancing the efficiency of cognitive and motor training; and treating peripheral disorders, including renal, respiratory, gastrointestinal, liver, genitourinary, metabolic, and inflammatory disorders.

Abstract: Acoustic filters, resonators and methods are disclosed. An acoustic filter device includes a substrate; a piezoelectric layer attached to the substrate, wherein at least a portion of the piezoelectric layer is disposed over a cavity of the acoustic resonator device; and an interdigital transducer (IDT) on a surface of the piezoelectric layer, the IDT including interleaved fingers extending at least over the portion of the piezoelectric layer disposed over the cavity. The cavity has at least one rounded corner, and a portion of interleaved fingers extend from at least one busbar. Moreover, at least a portion of the rounded corner of the cavity is under the at least one busbar in a plan view of the piezoelectric layer.

Abstract: The present application is directed to a method and system for restraining a patient before, during, or after surgery that increases efficiency of the surgical setup process and minimizes risk of musculoskeletal damage to the patient, particularly in surgeries requiring a patient to be in a Trendelenburg position (e.g., robotic or laparoscopic surgeries). One or more restraints can be worn by a patient prior to surgery', and may function to redistribute the patient's weight across the patient's torso to reduce strain on the patient's shoulders and back. The restraint(s) can be attached to a surgical table by way of an attachment mechanism coupled to the restraint(s) and the table. The attachment mechanism can secure the patient to the table by way of one or more straps, clips, and/or other intermediates. Optionally, the restraint(s) can fulfill other surgical needs, such as heat regulation and vascular compression.

Abstract: Various embodiments of a vaporization device are described that include one or more features, such as for generating a combined inhalable aerosol. In some embodiments, the vaporization device can include one or more heaters that are configured to heat one or more vaporizable materials. Various embodiments of heating elements and heating systems for use in vaporization devices are also described.

Abstract: Acquisition-distribution-layers (ADL) comprising a hydroentangled composite are provided. The hydroentangled composite includes (a) a first outer layer including a first plurality of synthetic fibers, (b) a second outer layer including a second plurality of synthetic fibers, and (c) at least one core layer including cellulose fibers comprising natural cellulose fibers, synthetic cellulose fibers, or a combination thereof, in which the at least one core layer is located directly or indirectly between the first outer layer and the second outer layer. The first plurality of synthetic fibers, the second plurality of synthetic fibers, and the cellulose fibers are physically entangled together. The hydroentangled composite further comprises a three-dimensional topography defined by a first outermost surface of the hydroentangled composite, in which the three-dimensional topography includes a plurality raised portions and a plurality of recessed portions.