Patents by Inventor Andrew Georgiadis

Andrew Georgiadis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for Microsatellite Instability Detection
    Publication number: 20230160002
    Abstract: The invention provides methods for determining the MSI status of a patient by liquid biopsy with sample preparation using hybrid capture and non-unique barcodes. In certain aspects, the invention provides a method of detecting microsatellite instability (MSI). The method includes obtaining cell-free DNA (cfDNA) from a sample of blood or plasma from a patient and sequencing portions of the cfDNA to obtain sequences of a plurality of tracts of nucleotide repeats in the cfDNA. A report is provided describing an MSI status in the patient when a distribution of lengths of the plurality of tracts has peaks that deviate significantly from peaks in a reference distribution.
    Type: Application
    Filed: January 18, 2023
    Publication date: May 25, 2023
    Applicant: Personal Genome Diagnostics Inc.
    Inventors: Andrew Georgiadis, Mark Sausen
  • Process for microsatellite instability detection
    Patent number: 11597967
    Abstract: The invention provides methods for determining the MSI status of a patient by liquid biopsy with sample preparation using hybrid capture and non-unique barcodes. In certain aspects, the invention provides a method of detecting microsatellite instability (MSI). The method includes obtaining cell-free DNA (cfDNA) from a sample of blood or plasma from a patient and sequencing portions of the cfDNA to obtain sequences of a plurality of tracts of nucleotide repeats in the cfDNA. A report is provided describing an MSI status in the patient when a distribution of lengths of the plurality of tracts has peaks that deviate significantly from peaks in a reference distribution.
    Type: Grant
    Filed: November 29, 2018
    Date of Patent: March 7, 2023
    Assignee: Personal Genome Diagnostics Inc.
    Inventors: Andrew Georgiadis, Mark Sausen
  • PROCESS FOR MICROSATELLITE INSTABILITY DETECTION
    Publication number: 20190169685
    Abstract: The invention provides methods for determining the MSI status of a patient by liquid biopsy with sample preparation using hybrid capture and non-unique barcodes. In certain aspects, the invention provides a method of detecting microsatellite instability (MSI). The method includes obtaining cell-free DNA (cfDNA) from a sample of blood or plasma from a patient and sequencing portions of the cfDNA to obtain sequences of a plurality of tracts of nucleotide repeats in the cfDNA. A report is provided describing an MSI status in the patient when a distribution of lengths of the plurality of tracts has peaks that deviate significantly from peaks in a reference distribution.
    Type: Application
    Filed: November 29, 2018
    Publication date: June 6, 2019
    Inventors: Andrew Georgiadis, Mark Sausen