Patents by Inventor Andrew GIESSEL

Andrew GIESSEL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210217484
    Abstract: Techniques for manufacturing a variant of a target protein. The techniques may include accessing a latent variable statistical model (LVSM) configured to generate output indicating one or more biological sequences corresponding to one or more variants of the target protein and using the LVSM to generate a first output indicating a first biological sequence associated with a first variant of the target protein. The techniques further include manufacturing, using the first biological sequence, a first biological molecule to produce the first variant of the target protein.
    Type: Application
    Filed: January 8, 2021
    Publication date: July 15, 2021
    Applicant: ModernaTX, Inc.
    Inventors: Andrew Giessel, Athanasios Dousis, Iain McFadyen
  • Publication number: 20210163922
    Abstract: The present invention relates to a rapid, high-fidelity process to support synthesis of genes for in vitro transcription of modified messenger RNA. In this process, sequence errors resulting from amplification with oligonucleotides comprising inherent errors are significantly reduced.
    Type: Application
    Filed: March 19, 2019
    Publication date: June 3, 2021
    Inventors: Marcus R. DUVALL, Kevin SMITH, Robin HUANG, Andrew GIESSEL