Patents by Inventor Andrew Gregory York

Andrew Gregory York has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • System and method for inferring protein binding
    Patent number: 11709136
    Abstract: Methods and apparatus for inferring protein binding based on rotational diffusion of a collection of fluorophores.
    Type: Grant
    Filed: June 17, 2019
    Date of Patent: July 25, 2023
    Assignee: CALICO LIFE SCIENCES LLC
    Inventors: Andrew Gregory York, Maria Del Mar Ingaramo
  • OBLIQUE PLANE MICROSCOPY SYSTEM AND METHOD
    Publication number: 20220260818
    Abstract: Systems and methods for oblique plane microscopy are disclosed.
    Type: Application
    Filed: February 26, 2020
    Publication date: August 18, 2022
    Inventors: Alfred Millett-Sikking, Andrew Gregory York
  • SYSTEM AND METHOD FOR INFERRING PROTEIN BINDING
    Publication number: 20210247315
    Abstract: Methods and apparatus for inferring protein binding based on rotational diffusion of a collection of fluorophores.
    Type: Application
    Filed: June 17, 2019
    Publication date: August 12, 2021
    Inventors: Andrew Gregory York, Maria Del Mar Ingaramo
  • Fluorescence microscopy system and methods based on stimulated emission
    Patent number: 11009463
    Abstract: Fluorescence imaging based on stimulated emission. In one example a system includes an excitation source (110) that excites fluorescent markers (122) in a sample (120) with an excitation beam (112), a stimulation source (130) that stimulates the excited fluorescent markers (122) to produce stimulated emission (124), and an objective lens (150) that receives the stimulation beam (132) and the stimulated emission (124). The system further includes a phase shifting and attenuation apparatus (200) configured to receive the stimulation beam (132) and the stimulated emission (124) from the objective lens (150), to attenuate the stimulation beam (132), and to induce a relative phase shift between a reference beam (optionally being at least a portion of the stimulation beam) and the stimulated emission, thereby causing constructive interference between the reference beam and the stimulated emission.
    Type: Grant
    Filed: April 11, 2018
    Date of Patent: May 18, 2021
    Assignee: CALICO LIFE SCIENCES LLC
    Inventors: Andrew Gregory York, Sanjay Ramesh Varma
  • FLUORESCENCE MICROSCOPY SYSTEM AND METHODS BASED ON STIMULATED EMISSION
    Publication number: 20200378895
    Abstract: Fluorescence imaging based on stimulated emission. In one example a system includes an excitation source (110) that excites fluorescent markers (122) in a sample (120) with an excitation beam (112), a stimulation source (130) that stimulates the excited fluorescent markers (122) to produce stimulated emission (124), and an objective lens (150) that receives the stimulation beam (132) and the stimulated emission (124). The system further includes a phase shifting and attenuation apparatus (200) configured to receive the stimulation beam (132) and the stimulated emission (124) from the objective lens (150), to attenuate the stimulation beam (132), and to induce a relative phase shift between a reference beam (optionally being at least a portion of the stimulation beam) and the stimulated emission, thereby causing constructive interference between the reference beam and the stimulated emission.
    Type: Application
    Filed: April 11, 2018
    Publication date: December 3, 2020
    Inventors: Andrew Gregory York, Sanjay Ramesh Varma