Patents by Inventor Andrew H. Koehl
Andrew H. Koehl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11530964Abstract: A sensor system comprising a housing having an inlet aperture through which fluid enters the housing and a conditioning material in the housing, the conditioning material being adapted to control levels of a substance within the housing. The sensor system comprises a sensor for analysing the fluid in the housing. The sensor system comprises circulation means which is configured to alternate circulation of fluid within the housing between a sensing fluid path in which the fluid is analysed by the sensor and a second fluid path in which the fluid flow is conditioned. A method for analysing fluid in a housing using a sensor is also provided.Type: GrantFiled: August 7, 2018Date of Patent: December 20, 2022Assignees: OWLSTONE MEDCIAL LIMITED, OWLSTONE INC.Inventors: Andrew H. Koehl, Max Allsworth
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Publication number: 20210055186Abstract: A sensor system comprising a housing having an inlet aperture through which fluid enters the housing and a conditioning material in the housing, the conditioning material being adapted to control levels of a substance within the housing. The sensor system comprises a sensor for analysing the fluid in the housing. The sensor system comprises circulation means which is configured to alternate circulation of fluid within the housing between a sensing fluid path in which the fluid is analysed by the sensor and a second fluid path in which the fluid flow is conditioned. A method for analysing fluid in a housing using a sensor is also provided.Type: ApplicationFiled: August 7, 2018Publication date: February 25, 2021Applicants: OWLSTONE MEDCIAL LIMITED, OWLSTONE INC.Inventors: Andrew H. Koehl, Max Allsworth
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Publication number: 20210007627Abstract: Mobile device (110) is disclosed. The present techniques relate to a mobile device or portable electronic device, particularly a device including a breath sampling device. The mobile electronic device (110) comprises a collection device (112) for collecting and storing a gas sample. The collection device (112) is accessible to enable analysis of the gas stored in the collection device (112). The collection device (112) comprises a mouthpiece (118) into which a user exhales. The collection device (112) further comprises a plurality of sorbent tubes (114) to collect and store the breath sample(s). Each tube (114) has a one-way valve (116) to prevent captured breath escaping.Type: ApplicationFiled: March 12, 2019Publication date: January 14, 2021Applicants: Owlstone Medical Limited, Owlstone Inc.Inventors: Andrew H. Koehl, Max Allsworth
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Patent number: 10012614Abstract: An ion filter and a method of manufacturing an ion filter. The method including providing a monolithic structure; selectively removing regions of the structure, to form a pair of electrodes defining at least one ion channel therebetween. The electrodes are preferably mechanically connected at one or more locations by a portion of the structure; wherein the connecting portion of the structure provides a higher electrical impedance than the filter would provide without such a mechanical connection, to thereby electrically separate the electrodes.Type: GrantFiled: October 28, 2016Date of Patent: July 3, 2018Assignee: Owlstone Medical LimitedInventors: Matthew Hart, Andrew H. Koehl
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Patent number: 10002750Abstract: Ion filter for FAIMS fabricated using the LIGA technique. The ion filter is manufactured using a metal layer to form the ion channels and an insulating support layer to hold the structure rigidly together after separation of the metal layer into two electrodes.Type: GrantFiled: May 11, 2016Date of Patent: June 19, 2018Assignee: Owlstone Medical LimitedInventors: Danielle Toutoungi, Matthew Hart, John Somerville, Jon Pearson, Max Allsworth, Richard Orrell, Antoni Negri, Jeremy Spinks, Martin Holden, Andrew H. Koehl, Alastair Taylor
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Patent number: 9588081Abstract: An ion filter and a method of manufacturing an ion filter. The method including providing a monolithic structure; selectively removing regions of the structure, to form a pair of electrodes defining at least one ion channel therebetween. The electrodes are preferably mechanically connected at one or more locations by a portion of the structure; wherein the connecting portion of the structure provides a higher electrical impedance than the filter would provide without such a mechanical connection, to thereby electrically separate the electrodes.Type: GrantFiled: October 8, 2015Date of Patent: March 7, 2017Assignee: Ownstone Medical LimitedInventors: Matthew Hart, Andrew H. Koehl
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Publication number: 20170045477Abstract: An ion filter and a method of manufacturing an ion filter. The method including providing a monolithic structure; selectively removing regions of the structure, to form a pair of electrodes defining at least one ion channel therebetween. The electrodes are preferably mechanically connected at one or more locations by a portion of the structure; wherein the connecting portion of the structure provides a higher electrical impedance than the filter would provide without such a mechanical connection, to thereby electrically separate the electrodes.Type: ApplicationFiled: October 28, 2016Publication date: February 16, 2017Applicant: Ownstone Medical LimitedInventors: Matthew Hart, Andrew H. Koehl
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Publication number: 20160336159Abstract: Ion filter for FAIMS fabricated using the LIGA technique. The ion filter is manufactured using a metal layer to form the ion channels and an insulating support layer to hold the structure rigidly together after separation of the metal layer into two electrodes.Type: ApplicationFiled: May 11, 2016Publication date: November 17, 2016Applicant: Owlstone LimitedInventors: Danielle Toutoungi, Matthew Hart, John Somerville, Jon Pearson, Max Allsworth, Richard Orrell, Antoni Negri, Jeremy Spinks, Martin Holden, Andrew H. Koehl, Alastair Taylor
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Patent number: 9362099Abstract: Ion filter for FAIMS fabricated using the LIGA technique. The ion filter is manufactured using a metal layer to form the ion channels and an insulating support layer to hold the structure rigidly together after separation of the metal layer into two electrodes.Type: GrantFiled: January 3, 2013Date of Patent: June 7, 2016Assignee: Owlstone LimitedInventors: Danielle Toutoungi, Matthew Hart, John Somerville, Jon Pearson, Max Allsworth, Richard Orrell, Antoni Negri, Jeremy Spinks, Martin Holden, Andrew H. Koehl, Alastair Taylor
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Publication number: 20160025679Abstract: An ion filter and a method of manufacturing an ion filter. The method including providing a monolithic structure; selectively removing regions of the structure, to form a pair of electrodes defining at least one ion channel therebetween. The electrodes are preferably mechanically connected at one or more locations by a portion of the structure; wherein the connecting portion of the structure provides a higher electrical impedance than the filter would provide without such a mechanical connection, to thereby electrically separate the electrodes.Type: ApplicationFiled: October 8, 2015Publication date: January 28, 2016Applicant: Owlstone LimitedInventors: Matthew Hart, Andrew H. Koehl
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Publication number: 20150028196Abstract: Ion filter for FAIMS fabricated using the LIGA technique. The ion filter is manufactured using a metal layer to form the ion channels and an insulating support layer to hold the structure rigidly together after separation of the metal layer into two electrodes.Type: ApplicationFiled: January 3, 2013Publication date: January 29, 2015Inventors: Danielle Toutoungi, Matthew Hart, John Somerville, Jon Pearson, Max Allsworth, Richard Orrell, Antoni Negri, Jeremy Spinks, Martin Holden, Andrew H. Koehl, Alistair Taylor
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Patent number: 8487240Abstract: A method and sensor for monitoring chemical species in a gas flow are described. An ionized sample of gas is passed through a flow channel, with a DC electric field applied transverse to the longitudinal axis of the channel. Any electric current produced by the ion flow is measured, with variations in the current being indicative of a change in composition of the gas flow. In certain embodiments, the DC field may be varied over time, to sweep the field voltage. The detected current against field voltage graph may be taken as a profile of a particular gas composition. Variations in the profile again are indicative of a change in gas composition.Type: GrantFiled: September 21, 2010Date of Patent: July 16, 2013Assignee: Owlstone Inc.Inventor: Andrew H. Koehl
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Patent number: 8319177Abstract: An ion mobility spectrometer is described having an ion filter in the form of at least one ion channel having a plurality of electrodes. A time-varying electric potential applied to the conductive layers allows the filler to selectively admit ion species. The electric potential has a drive and a transverse component, and in preferred embodiments each of the electrodes is involved in generating a component of both the drive and transverse fields. The device may be used without a drift gas flow. Microfabrication techniques are described for producing microscale spectrometers, as are various uses of the spectrometer.Type: GrantFiled: May 6, 2010Date of Patent: November 27, 2012Assignee: Owlstone Ltd.Inventors: Paul Boyle, Andrew H. Koehl, David Ruiz-Alonso
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Publication number: 20120273668Abstract: A smart FAIMS sensor system and method includes a 2/2-electrode filter that pumps the ions through the system and separates the ionic species, a detector for collecting the separated ions and generating a detector signal in response to the collected ions, and a controller configured to change the operating parameters of the system in response to changes in the sensor's environment detected by the sensor. The ability to dynamically change the operating parameters of the sensor enables the sensor to maintain high sensitivity to environmental threats while decreasing the incidences of false positive events.Type: ApplicationFiled: July 10, 2012Publication date: November 1, 2012Applicant: Owlstone Nanotech Inc.Inventors: Ashley Wilks, Paul Boyle, Andrew H. Koehl, Russell Parris, David Ruiz-Alonso, Martyn Rush
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Patent number: 8258466Abstract: A smart FAIMS sensor system and method includes a 2/2-electrode filter that pumps the ions through the system and separates the ionic species, a detector for collecting the separated ions and generating a detector signal in response to the collected ions, and a controller configured to change the operating parameters of the system in response to changes in the sensor's environment detected by the sensor. The ability to dynamically change the operating parameters of the sensor enables the sensor to maintain high sensitivity to environmental threats while decreasing the incidences of false positive events.Type: GrantFiled: May 6, 2010Date of Patent: September 4, 2012Assignee: Owlstone Nanotech IncInventors: Paul Boyle, Martyn Rush, David Ruiz-Alonso, Andrew H. Koehl, Russell Parris, Ashley Wilks
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Publication number: 20110056371Abstract: A method and sensor for monitoring chemical species in a gas flow are described. An ionized sample of gas is passed through a flow channel, with a DC electric field applied transverse to the longitudinal axis of the channel. Any electric current produced by the ion flow is measured, with variations in the current being indicative of a change in composition of the gas flow. In certain embodiments, the DC field may be varied over time, to sweep the field voltage. The detected current against field voltage graph may be taken as a profile of a particular gas composition. Variations in the profile again are indicative of a change in gas composition.Type: ApplicationFiled: September 21, 2010Publication date: March 10, 2011Inventor: Andrew H. Koehl
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Publication number: 20100213364Abstract: A smart FAIMS sensor system and method includes a 2/2-electrode filter that pumps the ions through the system and separates the ionic species, a detector for collecting the separated ions and generating a detector signal in response to the collected ions, and a controller configured to change the operating parameters of the system in response to changes in the sensor's environment detected by the sensor. The ability to dynamically change the operating parameters of the sensor enables the sensor to maintain high sensitivity to environmental threats while decreasing the incidences of false positive events.Type: ApplicationFiled: May 6, 2010Publication date: August 26, 2010Inventors: Ashley Wilks, Paul Boyle, Andrew H. Koehl, Russell Parris, David Ruiz-Alonso, Martyn Rush
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Patent number: 7714277Abstract: A smart FAIMS sensor system and method includes a 2/2-electrode filter that pumps the ions through the system and separates the ionic species, a detector for collecting the separated ions and generating a detector signal in response to the collected ions, and a controller configured to change the operating parameters of the system in response to changes in the sensor's environment detected by the sensor. The ability to dynamically change the operating parameters of the sensor enables the sensor to maintain high sensitivity to environmental threats while decreasing the incidences of false positive events.Type: GrantFiled: July 20, 2006Date of Patent: May 11, 2010Assignee: Owlstone Nanotech, Inc.Inventors: Ashley Wilks, Paul Boyle, Andrew H. Koehl, Russell Parris, David Ruiz-Alonso, Martyn Rush
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Patent number: 7573028Abstract: The present invention relates to an ion drive for selectively isolating an analyte of interest and methods of use thereof. The ion drive includes a substrate with channels therethrough, a conductive material coating on the bottom and top of the substrate, a top electrical lead connected to the conductive material coating covering the top of the substrate, and a bottom electrical lead connected to the conductive material coating covering the bottom of the substrate. The invention further relates to an odor emitter which is made up of an ion drive mounted towards the top of a vessel.Type: GrantFiled: October 26, 2005Date of Patent: August 11, 2009Assignee: Owlstone Nanotech, Inc.Inventors: Russell Parris, David Ruiz-Alonso, Andrew H. Koehl, Martyn Rush, Paul Boyle, Ashley Wilks
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Publication number: 20080017791Abstract: A smart FAIMS sensor system and method includes a 2/2-electrode filter that pumps the ions through the system and separates the ionic species, a detector for collecting the separated ions and generating a detector signal in response to the collected ions, and a controller configured to change the operating parameters of the system in response to changes in the sensor's environment detected by the sensor. The ability to dynamically change the operating parameters of the sensor enables the sensor to maintain high sensitivity to environmental threats while decreasing the incidences of false positive events.Type: ApplicationFiled: July 20, 2006Publication date: January 24, 2008Applicant: Owlstone Nanotech Inc.Inventors: Ashley Wilks, Paul Boyle, Andrew H. Koehl, Russell Parris, David Ruiz-Alonso, Martyn Rush