Patents by Inventor ANDREW HEARN
ANDREW HEARN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9932620Abstract: A rapid, sensitive method of separating and detecting microorganisms from a sample potentially containing microorganisms, such as but not limited to bacteria, fungi, yeast, viruses, and the like. The method relies on separation techniques to separate and concentrate the cells from the sample, together with chemical techniques to amplify the amount of detectable signal from low numbers of cells to provide a rapid and sensitive method of detecting microorganisms. This detection method may utilize: a filtration device; a centrifugation device; a system; a swab device; and kit comprising one or more of the devices and components to perform the present method of separating and detecting microorganisms in a sample potentially containing microorganisms. The sample may be a chemical, cosmetic, personal care, pharmaceutical, or consumable good in its raw material, in-process, and/or finished product states that needs to be tested for any contaminating microorganisms prior to shipment to the consumer.Type: GrantFiled: June 29, 2012Date of Patent: April 3, 2018Assignee: CELSIS LTD.Inventors: Subramani Sellappan, Andrew Hearn, Salvatore Seminara
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Publication number: 20150322476Abstract: A rapid, sensitive method of separating and detecting microorganisms from a sample potentially containing microorganisms, such as but not limited to bacteria, fungi, yeast, viruses, and the like. The method relies on separation techniques to separate and concentrate the cells from the sample, together with chemical techniques to amplify the amount of detectable signal from low numbers of cells to provide a rapid and sensitive method of detecting microorganisms. This detection method may utilize: a filtration device; a centrifugation device; a system; a swab device; and kit comprising one or more of the devices and components to perform the present method of separating and detecting microorganisms in a sample potentially containing microorganisms. The sample may be a chemical (e.g., household cleaners), cosmetic, personal care, pharmaceutical, or consumable (e.g.Type: ApplicationFiled: May 21, 2013Publication date: November 12, 2015Applicant: Celsis International LimitedInventors: Subramani SELLAPPAN, Andrew HEARN, Salvatore SEMINARA
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Publication number: 20150140583Abstract: A rapid, sensitive method of separating and detecting microorganisms from a sample containing microorganisms, such as but not limited to bacteria, fungi, yeast, viruses, and the like. The method relies on separation techniques to separate and concentrate the cells from the sample, together with chemical techniques to amplify the amount of detectable signal from low numbers of cells to provide a rapid and sensitive method of detecting microorganisms. This detection method may utilize: a filtration device; a centrifugation device; a system; a swab device; and kit comprising one or more of the devices and components to perform the present method of separating and detecting microorganisms in a sample containing microorganisms. The sample may be a chemical, cosmetic, personal care, pharmaceutical, or consumable good in its raw material, in-process, and/or finished product states that needs to be tested for any contaminating microorganisms prior to shipment to the consumer.Type: ApplicationFiled: May 21, 2013Publication date: May 21, 2015Applicant: Celsis International LimitedInventors: Andrew Hearn, Lori Daane
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Publication number: 20130309700Abstract: A rapid, sensitive method of separating and detecting microorganisms from a sample containing microorganisms, such as but not limited to bacteria, fungi, yeast, viruses, and the like. The method relies on separation techniques to separate and concentrate the cells from the sample, together with chemical techniques to amplify the amount of detectable signal from low numbers of cells to provide a rapid and sensitive method of detecting microorganisms. This detection method may utilize: a filtration device; a centrifugation device; a system; a swab device; and kit comprising one or more of the devices and components to perform the present method of separating and detecting microorganisms in a sample containing microorganisms. The sample may be a chemical, cosmetic, personal care, pharmaceutical, or consumable good in its raw material, in-process, and/or finished product states that needs to be tested for any contaminating microorganisms prior to shipment to the consumer.Type: ApplicationFiled: March 15, 2013Publication date: November 21, 2013Applicant: Celsis International LimitedInventors: Andrew Hearn, Lori Daane
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Publication number: 20120301907Abstract: A rapid, sensitive method of separating and detecting microorganisms from a sample potentially containing microorganisms, such as but not limited to bacteria, fungi, yeast, viruses, and the like. The method relies on separation techniques to separate and concentrate the cells from the sample, together with chemical techniques to amplify the amount of detectable signal from low numbers of cells to provide a rapid and sensitive method of detecting microorganisms. This detection method may utilize: a filtration device; a centrifugation device; a system; a swab device; and kit comprising one or more of the devices and components to perform the present method of separating and detecting microorganisms in a sample potentially containing microorganisms. The sample may be a chemical, cosmetic, personal care, pharmaceutical, or consumable good in its raw material, in-process, and/or finished product states that needs to be tested for any contaminating microorganisms prior to shipment to the consumer.Type: ApplicationFiled: June 29, 2012Publication date: November 29, 2012Applicant: CELSIS LTD.Inventors: SUBRAMANI SELLAPPAN, ANDREW HEARN, SALVATORE SEMINARA
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Publication number: 20090203017Abstract: The invention relates to methods for the determination and detection of nucleic acids sequences in a sample. The nucleic acid may be RNA or DNA or both. The invention also relates to methods for the determination of the presence and species of various microorganisms in a sample. We have also identified a set of oligonucleotide nucleic acid sequences within the rRNAs of Gram-negative organisms that facilitates both the broad identification of Gram-negative organisms as a class when used as a pool, or in combination, for example in a hybridization assay. This set of oligonucleotides may detect sequences that are indicative of the presence of organisms of the broad class of Gram-negative organisms while exhibiting little or no false identification of Gram-positive organisms, and fungi, or other microorganisms. The assay includes concurrent incubation with at least one nucleotide sequence of interest, at least one nucleic acid probe, a fluorosurfactant, and a nuclease.Type: ApplicationFiled: January 23, 2009Publication date: August 13, 2009Applicants: BLOVENTURES, INC., Celsis International plcInventors: ELLIOTT P. DAWSON, STEVEN J. SIMMONS, LORI J. RAY-COX, JENNIFER M. BAKER, KRISTIE E. WOMBLE, JUDITH MADDEN, SUBRAMANI SELLAPPAN, ANDREW HEARN, SAL SEMINARA
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Publication number: 20080182235Abstract: The invention relates to the encapsulation of luminescence-related molecules, including but not limited to, adenosine triphosphate (ATP), adenylate kinase (AK), alkaline phosphatase (ALP), luminol and luciferin/luciferase cocktails, within liposomes. These liposomes can be employed to enhance the luminescence detection of microorganisms and compounds in various products and samples. The liposomes containing the luminescence-related molecules can bear a probe which has a specific sequence or structure that, in turn can be used to hybridize to, or couple with, a portion of the target analyte. Within the same assay, paramagnetic beads can bear a probe having a specific sequence or structure that, can hybridize to, or couple with, a second portion of the target analyte to create a complex of analyte bound to paramagnetic beads and liposomes. This type of assay can be often referred to as a ‘sandwich’ assay.Type: ApplicationFiled: January 30, 2007Publication date: July 31, 2008Applicants: Celsis International plc, Cornell UniversityInventors: Andrew Hearn, Judith Madden, Subramani Sellappan, Antje J. Baeumner, Natalya V. Zaytseva
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Publication number: 20050042661Abstract: A method for effecting a rapid, comprehensive release of cellular contents, including nucleotides and associated molecules of interest from living cells, using a novel family of quaternary ammonium compounds. Modification of the alkyl chain length of these compounds can enable selective release from different classes of living cells, allowing them to be rapidly distinguished from each other.Type: ApplicationFiled: August 12, 2004Publication date: February 24, 2005Inventors: Veikko Tarkkanen, Andreas Schafer, Andrew Hearn