Abstract: Disclosed is an agent which promotes the selective uptake of material by particular cell types. In particular, disclosed are targeting peptides which promote uptake of a material by for example endothelial cells. Also disclosed is a pharmaceutical composition comprising a targeting peptide in association with a vehicle and a method of targeting a material to a cell, comprising bringing into association the targeting peptide according to the present invention with the material to be targeted to form a complex and exposing the complex to a cell(s).