Abstract: Automatic redirection in scale-out cluster environments that perform distributed deduplication is described. A system converts a request from a client into a remote procedure call for a scale-out cluster. If the remote procedure call is a type that uses client-side redirection, the system identifies the node in the scale-out-cluster that is the correct node for the remote procedure call. If the client is not connected by any physical connection to the correct node, the system physically connects the client to the correct node by creating a physical connection within the virtual connection from the client to the scale-out cluster. If the remote procedure call is a write request, the system deduplicates the write request's data, uses the physical connection from the client to the correct node to send the write request and the deduplicated data to the correct node, and enables the correct node to store the deduplicated data.

Abstract: An integrated system and method to achieve ESD robustness on an integrated circuit (IC) in a fully automated ASIC design environment is described. Electrical characteristics and electrical limits on the power network are translated to power route region constraints for each chip input/output (I/O) cell. Electrical limits on the signal network are translated into signal route region constraints for each chip I/O cell. These constraints are passed on to an I/O floorplanner (automatic placer of I/O cells) that analyzes trade-offs between these constraints. For I/O cells that can not be placed to satisfy both power and signal region constraints, the I/O floorplanner utilizes the knowledge of alternative power distribution structures to group I/Os and create local power grid structures that have the effect of relaxing the power region constraints. Instructions for creating these local power grid structures are passed on to the automatic power routing tool.

Abstract: A method for high throughput screening of probes is described. These probes are useful for characterization and measurement of unbound metabolites in a fluid sample, particularly characterization and measurement of levels of unbound free fatty acids. By practice of the disclosed invention, a profile of unbound metabolites can be determined for an individual which can be used to determine the individual's relative risk for disease such as stroke, cardiac disease and cancer.