Patents by Inventor Andrew J. Blacker

Andrew J. Blacker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240325102
    Abstract: A user interface for managing a robotic drive to control one or more elongated medical devices (EMDs) supported by respective two or more cassettes of the robotic drive includes a first area to indicate a first two or more cassettes of the robotic drive which are selected to simultaneously manipulate a first two or more EMDs supported thereby in response to actuation of a first control, and a second area to indicate a second one or more cassettes of the robotic drive which are selected to simultaneously manipulate a second one or more EMDs supported thereby in response to actuation of a second control.
    Type: Application
    Filed: June 14, 2024
    Publication date: October 3, 2024
    Inventors: Andrew Clark, Dino Kasvikis, Steven J. Blacker, Benjamin Hannon, Max Ayers, Alix Dorfman
  • Patent number: 12035989
    Abstract: A system includes a robotic drive comprising a plurality of cassettes, each cassette to move an elongated medical device (EMD) loaded therein, and an input module to issue instructions to the robotic drive. The input module includes a first two or more selection buttons to select a first two or more EMDs loaded in respective ones of the plurality of cassettes, a first control actuatable to cause issuance of an instruction to the robotic drive to simultaneously move each of the first two or more EMDs linearly, and a second control actuatable to cause issuance of an instruction to the robotic drive to simultaneously rotate each of the first two or more EMDs.
    Type: Grant
    Filed: July 15, 2022
    Date of Patent: July 16, 2024
    Assignee: Corindus, Inc.
    Inventors: Andrew Clark, Dino Kasvikis, Steven J. Blacker, Benjamin Hannon, Max Ayers, Alix Dorfman
  • Patent number: 5760249
    Abstract: This invention is concerned with an improved process for the synthesis of hydroxysulfone, which is a key intermediate in the synthesis of carbonic anhydrase inhibitors, especially dorzolamide. Carbonic anhydrase inhibitors are known to be effective in treating elevated intraocular pressure or glaucoma.
    Type: Grant
    Filed: August 28, 1996
    Date of Patent: June 2, 1998
    Assignees: Merck & Co., Inc., Zeneca Limited
    Inventors: David J. Mathre, Paul Sohar, David Moody, Andrew J. Blacker
  • Patent number: 5637738
    Abstract: Described herein is a process for the preparation of (1S,2R)-1,2-epoxy-1,2,3,4-tetrahydronaphthalene having the Formula (I): ##STR1## which comprises the steps of (a) hydrogenating the compound of Formula (II) to form cis-(1R, 2S)-1,2-dihydroxy-1,2,3,4-tetrahydronaphthalene having the Formula (V): ##STR2## (b) reacting the dihydroxy compound of Formula (V) with a sulphonyl halide of formula R.sup.1 SO.sub.2 Z wherein R.sup.1 is methyl, ethyl, trifluoromethyl, phenyl or p-tolyl, and Z is fluorine, chlorine, bromine or iodine to give a bis-sulphonyl ester of formula (X): ##STR3## and (c) treating the bis-sulphonyl ester (X) with an alkali metal carbonate or alkali metal hydroxide to give the compound of Formula (I).
    Type: Grant
    Filed: August 25, 1995
    Date of Patent: June 10, 1997
    Assignee: Zeneca Limited
    Inventors: Andrew J. Blacker, Stephen M. Brown, Derek R. Boyd, Gary N. Sheldrake
  • Patent number: 5527916
    Abstract: A process for the separation of at least one isomer from a mixture of isomers of a tetrahydropyran-2-one, having at least two chiral centers which comprises selective reaction of at least one isomer with a reagent catalyzed by a hydrolase enzyme whereby at least one isomer is preferentially converted into a distinct chemical species from the other isomers so that it is susceptible of separation by an appropriate chemical or physical separation process in which the tetrahydropyran-2-one is of Formula (1): ##STR1## wherein: Z is --H or a protecting group susceptible of reaction with the reagent under the influence of the enzyme; andY is formyl or protected formyl.
    Type: Grant
    Filed: August 1, 1994
    Date of Patent: June 18, 1996
    Assignee: Zeneca Limited
    Inventors: Andrew J. Blacker, John Crosby, John A. L. Herbert
  • Patent number: 5508444
    Abstract: Novel substituted cis-1,2-dihydroxy-cyclohexadiene compounds, useful as intermediates in the production of compounds for use as intermediates in the production of agrochemicals and pharmaceuticals, and a microbial process for the preparation thereof.
    Type: Grant
    Filed: November 17, 1994
    Date of Patent: April 16, 1996
    Assignee: Zeneca Limited
    Inventors: Andrew J. Blacker, Martin Brown, Martin C. Bowden
  • Patent number: 5443971
    Abstract: A process for the separation of at least one isomer from a mixture of isomers of a tetrahydropyran-2-one, having at least two chiral centers which comprises selective reaction of at least one isomer with a reagent catalyzed by a hydrolase enzyme whereby at least one isomer is preferentially converted into a distinct chemical species from the other isomers so that it is susceptible of separation by an appropriate chemical or physical separation process in which the tetrahydropyran-2-one is of Formula (1): ##STR1## wherein: Z is --H or a protecting group susceptible of reaction with the reagent under the influence of the enzyme; andY is formyl or protected formyl.
    Type: Grant
    Filed: September 17, 1992
    Date of Patent: August 22, 1995
    Assignee: Zeneca Limited
    Inventors: Andrew J. Blacker, John Crosby, John A. L. Herbert
  • Patent number: 5443970
    Abstract: A process for the separation of at least one isomer from a mixture of isomers of a tetrahydropyran-2-one, having at least two chiral centres, which comprises selective reaction of at least one isomer with a reagent catalysed by a hydrolase enzyme whereby at least one isomer is preferentially converted into a distinct chemical species from the other isomers so that it is susceptible of separation by an appropriate chemical or physical separation process in which the tetrahydropyranone is of Formula (1): ##STR1## wherein: Z is --H or a protecting group susceptible of reaction with the reagent under the influence of the enzyme; andY is optionally substituted hydrocarbyl.
    Type: Grant
    Filed: September 17, 1992
    Date of Patent: August 22, 1995
    Assignee: Zeneca Limited
    Inventors: Andrew J. Blacker, John Crosby, John A. L. Herbert