Patents by Inventor Andrew J. Ewald

Andrew J. Ewald has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Autoimmune antibodies for use in inhibiting cancer cell growth
    Patent number: 11938183
    Abstract: The present disclosure provides, among other things, compositions (e.g., autoantibodies) that inhibit the growth, viability, or mobility of (invasion by) a cancer cell. Also provided are applications, such as therapeutic and diagnostic methods, in which the agents are useful, as well as screening methods for identifying autoantibodies useful in the applications.
    Type: Grant
    Filed: July 2, 2021
    Date of Patent: March 26, 2024
    Assignee: The Johns Hopkins University
    Inventors: Andrew J. Ewald, Veena Padmanaban, Livia Casciola-Rosen, Antony Rosen
  • METHODS FOR IDENTIFYING MODULATORS OF NATURAL KILLER CELL INTERACTIONS
    Publication number: 20230357722
    Abstract: Disclosed herein, are methods for identifying a drug candidate for treating cancer metastasis. The method comprising culturing an embedded organoid/natural killer (NK) cell co-culture with a drug candidate; and measuring one or more metastatic properties of the embedded organoid or tumor-killing potential or tumor-promoting potential of the NK cells in the co-culture.
    Type: Application
    Filed: October 1, 2021
    Publication date: November 9, 2023
    Inventors: Isaac C. Chan, Andrew J. Ewald
  • AUTOIMMUNE ANTIBODIES FOR USE IN INHIBITING CANCER CELL GROWTH
    Publication number: 20220160868
    Abstract: The present disclosure provides, among other things, compositions (e.g., autoantibodies) that inhibit the growth, viability, or mobility of (invasion by) a cancer cell. Also provided are applications, such as therapeutic and diagnostic methods, in which the agents are useful, as well as screening methods for identifying autoantibodies useful in the applications.
    Type: Application
    Filed: July 2, 2021
    Publication date: May 26, 2022
    Inventors: Andrew J. Ewald, Veena Padmanaban, Livia Casciola-Rosen, Antony Rosen
  • AUTOIMMUNE ANTIBODIES FOR USE IN INHIBITING CANCER CELL GROWTH
    Publication number: 20180104331
    Abstract: The present disclosure provides, among other things, compositions (e.g., autoantibodies) that inhibit the growth, viability, or mobility of (invasion by) a cancer cell. Also provided are applications, such as therapeutic and diagnostic methods, in which the agents are useful, as well as screening methods for identifying autoantibodies useful in the applications.
    Type: Application
    Filed: May 11, 2016
    Publication date: April 19, 2018
    Inventors: Andrew J. Ewald, Veena Padmanaban, Livia Casciola-Rosen, Antony Rosen