Abstract: Systems and methods for providing a health coaching message are disclosed. The method may include processing an electronic audio file to generate audio pace data, storing the audio pace data, receiving the electronic audio file and pace data, collecting electronic fitness data during a fitness activity; generating activity pace data; and playing the electronic audio file based on a comparison of the audio pace data and the activity pace data.

Abstract: An injector sleeve for a cylinder head may include a lower portion, a middle portion, and an upper portion. The upper portion may have a maximum thickness along at least a portion of a length thereof, and a groove on an inner surface of the injector sleeve. The groove may have an upper planar surface that is normal to a longitudinal axis of the injector sleeve. A related method of removing an injector sleeve from a cylinder head may include inserting a removal tool into the injector sleeve, within the cylinder head, by a predetermined depth, engaging a surface of the removal tool with an upper planar surface of a groove on an inner surface of an upper portion of the injector sleeve, and pulling the removal tool outward from the cylinder head, thereby removing the injector sleeve from the cylinder head.

Abstract: In its many embodiments, the present invention provides certain 9-substituted amino triazolo quinazoline compounds of the structural Formula (I): and pharmaceutically acceptable salts thereof, wherein, ring A, R1 and R2 are as defined herein, pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other therapeutically active agents), and methods for their preparation and use, alone and in combination with other therapeutic agents, as antagonists of A2a and/or A2b receptors, and in the treatment of a variety of diseases, conditions, or disorders that are mediated, at least in part, by the adenosine A2a receptor and/or the adenosine A2b receptor.

Abstract: Compounds or their pharmaceutically acceptable salts can inhibit the G12D mutant of Kirsten rat sarcoma (KRAS) protein and are expected to have utility as therapeutic agents, for example, for treating cancer. The disclosure also provides pharmaceutical compositions which comprise compounds disclosed herein or pharmaceutically acceptable salts thereof. The disclosure also relates to methods for use of the compounds or their pharmaceutically acceptable salts in the therapy and prophylaxis of cancer and for preparing pharmaceuticals for this purpose.

Abstract: Systems and methods for providing a health coaching message are disclosed. The method may include processing an electronic audio file to generate audio pace data, storing the audio pace data, receiving the electronic audio file and pace data, collecting electronic fitness data during a fitness activity; generating activity pace data; and playing the electronic audio file based on a comparison of the audio pace data and the activity pace data.

Abstract: Systems and methods for providing a health coaching message are disclosed. The method may include processing an electronic audio file to generate audio pace data, storing the audio pace data, receiving the electronic audio file and pace data, collecting electronic fitness data during a fitness activity; generating activity pace data; and playing the electronic audio file based on a comparison of the audio pace data and the activity pace data.

Abstract: Systems and methods for providing a health coaching message are disclosed. The method may include collecting electronic fitness data related to a fitness activity; transmitting the electronic fitness data; receiving the electronic fitness data; collecting second electronic fitness data; generating comparison data related to the electronic fitness data and the second electronic fitness data to determine a first ranking and a second ranking; and displaying the first ranking and the second ranking.

Abstract: Systems and methods for modifying a fitness plan are disclosed. The method may include providing a user input; receiving a user selection; identifying electronic plan data stored in a database; receiving the electronic plan data on a portable electronic device; generating an electronic schedule of fitness activities based on the electronic plan data; receiving a second user selection related to the electronic schedule; and modifying the electronic schedule based on the second user selection.

Abstract: Systems and methods for providing a health coaching message to a user are disclosed. The method may include collecting electronic fitness data related to a fitness activity; receiving footwear electronic data related to the electronic fitness data; collecting second electronic fitness data related to a second fitness activity; receiving second footwear electronic data; generating footwear electronic mileage data; and displaying the footwear electronic mileage data.

Abstract: Systems and methods for electronically sharing information about health-related activities among users of portable performance monitoring systems are disclosed. The method may include determining first information corresponding to a health-related activity for a first individual using a first portable performance monitoring system; determining second information corresponding to a health-related activity for a second individual using a second portable performance monitoring system; wirelessly transmitting the first and second information from the first and second portable performance monitoring systems; receiving the first and second information using a computing device remotely located from the first or second individual during the activity; and generating a visual display based on the first and second information.

Abstract: In at least one embodiment, a method for presenting route traversal information includes displaying a route map comprising a route path representing a route previously traversed by an athlete, receiving a plurality of parameter data points based on the athlete's previous traversal of the route, generating a visual cue based on at least one of the plurality of parameter data points, and displaying the visual cue on the route path.

Abstract: Systems and methods for presenting route traversal information are disclosed. The method may include collecting electronic fitness data related to a fitness activity; generating electronic pace data; and displaying a route map and the electronic pace data on a display.

Abstract: Systems and methods for maintaining a health-related action database are disclosed. The method may include receiving first information corresponding to a health-related action of a first user on a first computing device; wirelessly transmitting the first information from the first computing device; receiving second information corresponding to a health-related action of a second user on a second computing device; wirelessly transmitting the second information from the second computing device; receiving the first information and the second information using a third computing device; and updating a database on the third computing device with the first information and the second information, where the first information comprises a description of the health-related action of the first user, and the second information comprises a description of the health-related action of the second user.

Abstract: In at least one embodiment, a method of providing an automated coaching message to a user of a portable electronic device includes determining first information corresponding to a health-related action for the user of the portable electronic device, transmitting the first information from the portable electronic device to a remotely located computing device, determining whether a coaching message should be provided, and receiving an automated coaching message based on the first information.

Abstract: Systems and methods for presenting route traversal information are disclosed. The method may include collecting electronic fitness data related to a fitness activity; generating electronic pace data; and displaying a route map and the electronic pace data on a display.

Abstract: Systems and methods for providing a health coaching message are disclosed. The method may include collecting electronic fitness data related to a fitness activity; transmitting the electronic fitness data; receiving the electronic fitness data; collecting second electronic fitness data; generating comparison data related to the electronic fitness data and the second electronic fitness data to determine a first ranking and a second ranking; and displaying the first ranking and the second ranking.

Abstract: Systems and methods for modifying a fitness plan are disclosed. The method may include providing a user input; receiving a user selection; identifying electronic plan data stored in a database; receiving the electronic plan data on a portable electronic device; generating an electronic schedule of fitness activities based on the electronic plan data; receiving a second user selection related to the electronic schedule; and modifying the electronic schedule based on the second user selection.

Abstract: Systems and methods for providing a health coaching message to a user are disclosed. The method may include collecting electronic fitness data related to a fitness activity; receiving footwear electronic data related to the electronic fitness data; collecting second electronic fitness data related to a second fitness activity; receiving second footwear electronic data; generating footwear electronic mileage data; and displaying the footwear electronic mileage data.

Abstract: Systems and methods for providing a health coaching message are disclosed. The method may include processing an electronic audio file to generate audio pace data, storing the audio pace data, receiving the electronic audio file and pace data, collecting electronic fitness data during a fitness activity; generating activity pace data; and playing the electronic audio file based on a comparison of the audio pace data and the activity pace data.

Abstract: Systems and methods for maintaining a health-related action database are disclosed. The method may include receiving first information corresponding to a health-related action of a first user on a first computing device; wirelessly transmitting the first information from the first computing device; receiving second information corresponding to a health-related action of a second user on a second computing device; wirelessly transmitting the second information from the second computing device; receiving the first information and the second information using a third computing device; and updating a database on the third computing device with the first information and the second information, where the first information comprises a description of the health-related action of the first user, and the second information comprises a description of the health-related action of the second user.