Patents by Inventor Andrew J. Jennings

Andrew J. Jennings has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Histone deacetylase inhibitors
    Patent number: 7642275
    Abstract: Compounds, pharmaceutical compositions, kits and methods are provided for use with histone deacetylases (HDACs) that comprise a compound of the formulae: wherein the variables are as defined herein.
    Type: Grant
    Filed: December 16, 2005
    Date of Patent: January 5, 2010
    Assignee: Takeda San Diego, Inc.
    Inventors: Jerome C. Bressi, Jason W. Brown, Robert J. Skene, Jeffrey A. Stafford, Phong H. Vu, Anthony R. Gangloff, Andrew J. Jennings, Stephen W. Kaldor
  • Kinase Inhibitors
    Publication number: 20080153869
    Abstract: The invention relates to compounds having one of the below formulae that may be used to inhibit kinases as well as compositions of matter and kits comprising these compounds, and methods using the compounds.
    Type: Application
    Filed: June 13, 2005
    Publication date: June 26, 2008
    Inventors: Jerome C. Bressi, Anthony R. Gangloff, David J. Hosfield, Andrew J. Jennings, Bheema R. Paraselli, Jeffrey A. Stafford
  • Histone deacetylase inhibitors
    Patent number: 7381825
    Abstract: Compounds that may be used to inhibit histone deacetylase having the formula Z-Q-L-M or Z-L-M wherein M is a substituent capable of complexing with a deacetylase catalytic site and/or a metal ion; L is a substituent providing between 0-10 atoms separation between the M substituent and the remainder of the compound; and Z and Q are as defined herein.
    Type: Grant
    Filed: March 17, 2004
    Date of Patent: June 3, 2008
    Assignee: Takeda San Diego, Inc.
    Inventors: Jerome C. Bressi, Jason W. Brown, Sheldon X. Cao, Anthony R. Gangloff, Andrew J. Jennings, Jeffrey A. Stafford, Phong H. Vu, Xiao-Yi Xiao
  • Histone deacetylase inhibitors
    Patent number: 7375228
    Abstract: Compounds that may be used to inhibit histone deacetylase having the formula Z-Q-L-M or Z-L-M wherein M is a substituent capable of complexing with a deacetylase catalytic site and/or a metal ion; L is a substituent providing between 0-10 atoms separation between the M substituent and the remainder of the compound; and Z and Q are as defined herein.
    Type: Grant
    Filed: March 17, 2004
    Date of Patent: May 20, 2008
    Assignee: Takeda San Diego, Inc.
    Inventors: Jerome C. Bressi, Jason W. Brown, Sheldon X. Cao, Anthony R. Gangloff, Andrew J. Jennings, Jeffrey A. Stafford, Phong H. Vu, Xiao-Yi Xiao
  • Crystallization of protein kinase B?/AKT1
    Patent number: 7309594
    Abstract: Provided are crystals relating to Protein kinase B?/AKT1 and its various uses.
    Type: Grant
    Filed: May 10, 2004
    Date of Patent: December 18, 2007
    Assignee: Takeda San Diego, Inc.
    Inventors: Alexei Brooun, Ellen Y. T. Chien, Douglas R. Dougan, Andrew J. Jennings, Michelle L. Kraus, Clifford D. Mol
  • Probe, assay and kits for detecting 11?-hydroxysteroid dehydrogenase and modulators thereof
    Patent number: 7235672
    Abstract: A probe, kit comprising the probe, and methods for using the probe are provided where the probe comprises: wherein DM is a detectable marker; and L is a straight or branched chain moiety providing between 1 and 20 atom separation between DM and the ring atom to which DM is attached.
    Type: Grant
    Filed: March 11, 2004
    Date of Patent: June 26, 2007
    Assignee: Takeda San Diego, Inc.
    Inventors: Christopher L. Caster, Andrew J. Jennings, Marc E. Navre, Michael B. Wallace, Yiqin Wu
  • Histone deacetylase inhibitors
    Patent number: 7169801
    Abstract: Compounds that may be used to inhibit histone deacetylase having the formula Z-Q-L-M or Z-L-M wherein M is a substituent capable of complexing with a deacetylase catalytic site and/or a metal ion; L is a substituent providing between 0–10 atoms separation between the M substituent and the remainder of the compound; and Z and Q are as defined herein.
    Type: Grant
    Filed: March 17, 2004
    Date of Patent: January 30, 2007
    Assignee: Takeda San Diego, Inc.
    Inventors: Jerome C. Bressi, Jason W. Brown, Sheldon X. Cao, Anthony R. Gangloff, Andrew J. Jennings, Jeffrey A. Stafford, Phong H. Vu, Xiao-Yi Xiao
  • Histone deacetylase inhibitors
    Publication number: 20040266769
    Abstract: Compounds that may be used to inhibit histone deacetylase having the formula
    Type: Application
    Filed: March 17, 2004
    Publication date: December 30, 2004
    Applicant: Syrrx, Inc.
    Inventors: Jerome C. Bressi, Jason W. Brown, Sheldon X. Cao, Anthony R. Gangloff, Andrew J. Jennings, Jeffrey A. Stafford, Phong H. Vu, Xiao-Yi Xiao
  • Histone deacetylase inhibitors
    Publication number: 20040254220
    Abstract: Compounds that may be used to inhibit histone deacetylase having the formula
    Type: Application
    Filed: March 17, 2004
    Publication date: December 16, 2004
    Applicant: Syrrx, Inc.
    Inventors: Jerome C. Bressi, Jason W. Brown, Sheldon X. Cao, Anthony R. Gangloff, Andrew J. Jennings, Jeffrey A. Stafford, Phong H. Vu, Xiao-Yi Xiao