Patents by Inventor Andrew J. O'brien

Andrew J. O'brien has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stabilizing Camptothecin Pharmaceutical Compositions
    Publication number: 20230108934
    Abstract: Irinotecan phospholipid liposomes with improved storage stability are provided, with related methods of treatment and manufacture. The irinotecan liposomes can have reduced formation of lyso-phosphatidylcholine (lyso-PC) during storage, and prior to administration to a patient.
    Type: Application
    Filed: August 31, 2022
    Publication date: April 6, 2023
    Applicant: Ipsen Biopharm Ltd.
    Inventors: Daryl C. Drummond, Dmitri B. Kirpotin, Mark Eamon Hayes, Charles Noble, Kevin Kesper, Antoine M. Awad, Douglas J. Moore, Andrew J. O'Brien
  • Stabilizing Camptothecin Pharmaceutical Compositions
    Publication number: 20210228567
    Abstract: Irinotecan phospholipid liposomes with improved storage stability are provided, with related methods of treatment and manufacture. The irinotecan liposomes can have reduced formation of lyso-phosphatidylcholine (lyso-PC) during storage, and prior to administration to a patient.
    Type: Application
    Filed: September 3, 2020
    Publication date: July 29, 2021
    Inventors: Daryl C. Drummond, Dmitri B. Kirpotin, Mark Eamon Hayes, Charles Noble, Kevin Kesper, Antoine M. Awad, Douglas J. Moore, Andrew J. O'Brien
  • Stabilizing Camptothecin Pharmaceutical Compositions
    Publication number: 20210205219
    Abstract: Irinotecan phospholipid liposomes with improved storage stability are provided, with related methods of treatment and manufacture. The irinotecan liposomes can have reduced formation of lyso-phosphatidylcholine (lyso-PC) during storage, and prior to administration to a patient.
    Type: Application
    Filed: March 22, 2021
    Publication date: July 8, 2021
    Applicant: Ipsen Biopharm Ltd.
    Inventors: Daryl C. Drummond, Dmitri B. Kirpotin, Mark E. Hayes, Charles Noble, Kevin Kesper, Antoine M. Awad, Douglas J. Moore, Andrew J. O'Brien
  • Stabilizing camptothecin pharmaceutical compositions
    Patent number: 10993914
    Abstract: Irinotecan phospholipid liposomes with improved storage stability are provided, with related methods of treatment and manufacture. The irinotecan liposomes can have reduced formation of lyso-phosphatidylcholine (lyso-PC) during storage, and prior to administration to a patient.
    Type: Grant
    Filed: September 11, 2019
    Date of Patent: May 4, 2021
    Inventors: Daryl C. Drummond, Dmitri B. Kirpotin, Mark Eamon Hayes, Charles Noble, Kevin Kesper, Antoine M. Awad, Douglas J. Moore, Andrew J. O'Brien
  • Stabilizing Camptothecin Pharmaceutical Compositions
    Publication number: 20200179371
    Abstract: Irinotecan phospholipid liposomes with improved storage stability are provided, with related methods of treatment and manufacture. The irinotecan liposomes can have reduced formation of lyso-phosphatidylcholine (lyso-PC) during storage, and prior to administration to a patient.
    Type: Application
    Filed: July 12, 2019
    Publication date: June 11, 2020
    Inventors: Daryl C. Drummond, Dmitri B. Kirpotin, Mark Eamon Hayes, Charles Noble, Kevin Kesper, Antoine M. Awad, Douglas J. Moore, Andrew J. O'Brien
  • Stabilizing Camptothecin Pharmaceutical Compositions
    Publication number: 20200069586
    Abstract: Irinotecan phospholipid liposomes with improved storage stability are provided, with related methods of treatment and manufacture. The irinotecan liposomes can have reduced formation of lyso-phosphatidylcholine (lyso-PC) during storage, and prior to administration to a patient.
    Type: Application
    Filed: September 11, 2019
    Publication date: March 5, 2020
    Applicant: Ipsen Biopharm Ltd.
    Inventors: Daryl C. Drummond, Dmitri B. Kirpotin, Mark Eamon Hayes, Charles Noble, Kevin Kesper, Antoine M. Awad, Douglas J. Moore, Andrew J. O'Brien
  • Stabilizing camptothecin pharmaceutical compositions
    Patent number: 10456360
    Abstract: Irinotecan phospholipid liposomes with improved storage stability are provided, with related methods of treatment and manufacture. The irinotecan liposomes can have reduced formation of lyso-phosphatidylcholine (lyso-PC) during storage, and prior to administration to a patient.
    Type: Grant
    Filed: October 15, 2016
    Date of Patent: October 29, 2019
    Assignee: Ipsen Biopharm Ltd.
    Inventors: Daryl C. Drummond, Dmitri B. Kirpotin, Mark Eamon Hayes, Charles Noble, Kevin Kesper, Antoine M. Awad, Douglas J. Moore, Andrew J. O'Brien
  • Stabilizing Camptothecin Pharmaceutical Compositions
    Publication number: 20190262331
    Abstract: Irinotecan phospholipid liposomes with improved storage stability are provided, with related methods of treatment and manufacture. The irinotecan liposomes can have reduced formation of lyso-phosphatidylcholine (lyso-PC) during storage, and prior to administration to a patient.
    Type: Application
    Filed: May 1, 2018
    Publication date: August 29, 2019
    Applicant: Ipsen Biopharm Ltd.
    Inventors: Daryl C. Drummond, Dmitri B. Kirpotin, Mark Eamon Hayes, Charles Noble, Kevin Kesper, Antoine M. Awad, Douglas J. Moore, Andrew J. O'Brien
  • Stabilizing Camptothecin Pharmaceutical Compositions
    Publication number: 20190105317
    Abstract: Irinotecan phospholipid liposomes with improved storage stability are provided, with related methods of treatment and manufacture. The irinotecan liposomes can have reduced formation of lyso-phosphatidylcholine (lyso-PC) during storage, and prior to administration to a patient.
    Type: Application
    Filed: May 1, 2018
    Publication date: April 11, 2019
    Applicant: Ipsen Biopharm Ltd.
    Inventors: Daryl C. Drummond, Dmitri B. Kirpotin, Mark Eamon Hayes, Charles Noble, Kevin Kesper, Antoine M. Awad, Douglas J. Moore, Andrew J. O'Brien
  • Stabilizing Camptothecin Pharmaceutical Compositions
    Publication number: 20180296484
    Abstract: Irinotecan phospholipid liposomes with improved storage stability are provided, with related methods of treatment and manufacture. The irinotecan liposomes can have reduced formation of lyso-phosphatidylcholine (lyso-PC) during storage, and prior to administration to a patient.
    Type: Application
    Filed: October 15, 2016
    Publication date: October 18, 2018
    Inventors: Daryl C. Drummond, Dmitri B. Kirpotin, Mark Eamon Hayes, Charles Noble, Kevin Kesper, Antoine M. Awad, Douglas J. Moore, Andrew J. O'Brien
  • Liposomal Irinotecan Preparations
    Publication number: 20180110771
    Abstract: Irinotecan phospholipid liposomes with improved storage stability are provided, with related methods of treatment and manufacture. The irinotecan liposomes can have reduced formation of lyso-phosphatidylcholine (lyso-PC) during storage, and prior to administration to a patient.
    Type: Application
    Filed: July 10, 2017
    Publication date: April 26, 2018
    Inventors: Daryl C. Drummond, Dmitri B. Kirpotin, Mark Eamon Hayes, Charles Noble, Kevin Kesper, Antoine M. Awad, Douglas J. Moore, Andrew J. O'Brien
  • Stabilizing Camptothecin Pharmaceutical Compositions
    Publication number: 20170319573
    Abstract: Irinotecan phospholipid liposomes with improved storage stability are provided, with related methods of treatment and manufacture. The irinotecan liposomes can have reduced formation of lyso-phosphatidylcholine (lyso-PC) during storage, and prior to administration to a patient.
    Type: Application
    Filed: July 27, 2017
    Publication date: November 9, 2017
    Inventors: Daryl C. Drummond, Dmitri B. Kirpotin, Mark Eamon Hayes, Charles Noble, Kevin Kesper, Antoine M. Awad, Douglas J. Moore, Andrew J. O'Brien
  • PROCESS FOR THE PREPARATION OF THE COMPOUND OSI-906
    Publication number: 20130123501
    Abstract: Process for preparing the tyrosine kinase inhibitor OSI-906 comprises coupling Compound (2) with Compound (6) under specified conditions.
    Type: Application
    Filed: July 29, 2011
    Publication date: May 16, 2013
    Inventors: Arlindo L. Castelhano, Gary A. Cutting, Andrew J. Locke, Kristen Michelle Mulvihill, Robert Norrie, Andrew J. O'brien, Stuart R. Park, Josef A. Rechka, Andrew MIchael Stevens, Christopher I. Thomas