Patents by Inventor Andrew J. Taberner
Andrew J. Taberner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11571519Abstract: The present invention relates to a method and corresponding apparatus for just in time mixing of a solid or powdered formulation and its subsequent delivery to a biological body. In some embodiments, a powdered formulation is maintained in a first chamber of a plurality of chambers. A plurality of electromagnetic actuators are in communication with the plurality of chambers. The actuators, when activated, generate a pressure within at least the first chamber. The pressure results in mixing of the powdered formulation and a diluent in time for delivering into the biological body.Type: GrantFiled: November 25, 2019Date of Patent: February 7, 2023Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventors: Ian W. Hunter, Andrew J. Taberner, N. Catherine Hogan
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Publication number: 20200164146Abstract: The present invention relates to a method and corresponding apparatus for just in time mixing of a solid or powdered formulation and its subsequent delivery to a biological body. In some embodiments, a powdered formulation is maintained in a first chamber of a plurality of chambers. A plurality of electromagnetic actuators are in communication with the plurality of chambers. The actuators, when activated, generate a pressure within at least the first chamber. The pressure results in mixing of the powdered formulation and a diluent in time for delivering into the biological body.Type: ApplicationFiled: November 25, 2019Publication date: May 28, 2020Inventors: Ian W. Hunter, Andrew J. Taberner, N. Catherine Hogan
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Patent number: 10485928Abstract: The present invention relate to a method and corresponding apparatus for just in time mixing of a solid or powdered formulation and its subsequent delivery to a biological body. In some embodiments, a powdered formulation is maintained in a first chamber of a plurality of chambers. A plurality of electromagnetic actuators are in communication with the plurality of chambers. The actuators, when activated, generate a pressure within at least the first chamber. The pressure results in mixing of the powdered formulation and a diluent in time for delivering into the biological body.Type: GrantFiled: October 10, 2017Date of Patent: November 26, 2019Assignee: Massachusetts Institute of TechnologyInventors: Ian W. Hunter, Andrew J. Taberner, N. Catherine Hogan
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Patent number: 10326347Abstract: A needle-free transdermal transport device for transferring a substance across a surface of a biological body includes a reservoir for storing the substance, a nozzle in fluid communication with the reservoir and a controllable electromagnetic actuator in communication with the reservoir. The actuator, referred to as a Lorentz force actuator, includes a stationary magnet assembly and a moving coil assembly. The coil assembly moves a piston having an end portion positioned within the reservoir. The actuator receives an electrical input and generates in response a corresponding force acting on the piston and causing a needle-free transfer of the substance between the reservoir and the biological body. The magnitude, direction and duration of the force are dynamically controlled (e.g., servo-controlled) by the electrical input and can be altered during the course of an actuation cycle. Beneficially, the actuator can be moved in different directions according to the electrical input.Type: GrantFiled: March 10, 2016Date of Patent: June 18, 2019Assignee: Massachusetts Institute of TechnologyInventors: Ian W. Hunter, Andrew J. Taberner, Brian D. Hemond, Dawn M. Wendell, Nora Catherine Hogan, Nathan B. Ball
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Publication number: 20180126080Abstract: The present invention relate to a method and corresponding apparatus for just in time mixing of a solid or powdered formulation and its subsequent delivery to a biological body. In some embodiments, a powdered formulation is maintained in a first chamber of a plurality of chambers. A plurality of electromagnetic actuators are in communication with the plurality of chambers. The actuators, when activated, generate a pressure within at least the first chamber. The pressure results in mixing of the powdered formulation and a diluent in time for delivering into the biological body.Type: ApplicationFiled: October 10, 2017Publication date: May 10, 2018Inventors: Ian W. Hunter, Andrew J. Taberner, N. Catherine Hogan
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Patent number: 9789256Abstract: The present invention relate to a method and corresponding apparatus for just in time mixing of a solid or powdered formulation and its subsequent delivery to a biological body. In some embodiments, a powdered formulation is maintained in a first chamber of a plurality of chambers. A plurality of electromagnetic actuators are in communication with the plurality of chambers. The actuators, when activated, generate a pressure within at least the first chamber. The pressure results in mixing of the powdered formulation and a diluent in time for delivering into the biological body.Type: GrantFiled: October 2, 2014Date of Patent: October 17, 2017Assignee: Massachusetts Institute of TechnologyInventors: Ian W. Hunter, Andrew J. Taberner, N. Catherine Hogan
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Publication number: 20170065769Abstract: A method for injecting a substance through a biological body surface includes providing a needle-free transdermal transport device configured to inject the substance through the surface. The substance is injected into the biological body with the transport device while a parameter of the injection is sensed and a servo-controller is used to dynamically adjust at least one injection characteristic based on the sensed parameter. The substance is injected for (i) a first time period during which a first portion of a volume of the substance is injected at a first injection pressure, and (ii) a second time period during which a remainder of the volume of the substance is injected at a second injection pressure. A viscosity of the substance may be determined, and a pressure calculated for injecting the substance based on the viscosity. The substance may be injected with the transport device by using the calculated pressure.Type: ApplicationFiled: October 28, 2016Publication date: March 9, 2017Inventors: Brian D. Hemond, Ian W. Hunter, Andrew J. Taberner, Dawn M. Wendell, N. Catherine Hogan
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Publication number: 20160197542Abstract: A needle-free transdermal transport device for transferring a substance across a surface of a biological body includes a reservoir for storing the substance, a nozzle in fluid communication with the reservoir and a controllable electromagnetic actuator in communication with the reservoir. The actuator, referred to as a Lorentz force actuator, includes a stationary magnet assembly and a moving coil assembly. The coil assembly moves a piston having an end portion positioned within the reservoir. The actuator receives an electrical input and generates in response a corresponding force acting on the piston and causing a needle-free transfer of the substance between the reservoir and the biological body. The magnitude, direction and duration of the force are dynamically controlled (e.g., servo-controlled) by the electrical input and can be altered during the course of an actuation cycle. Beneficially, the actuator can be moved in different directions according to the electrical input.Type: ApplicationFiled: March 10, 2016Publication date: July 7, 2016Inventors: Ian W. Hunter, Andrew J. Taberner, Brian D. Hemond, Dawn M. Wendell, Nora Catherine Hogan, Nathan B. Ball
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Patent number: 9308326Abstract: A needle-free transdermal transport device for transferring a substance across a surface of a biological body includes a reservoir for storing the substance, a nozzle in fluid communication with the reservoir and a controllable electromagnetic actuator in communication with the reservoir. The actuator, referred to as a Lorentz force actuator, includes a stationary magnet assembly and a moving coil assembly. The coil assembly moves a piston having an end portion positioned within the reservoir. The actuator receives an electrical input and generates in response a corresponding force acting on the piston and causing a needle-free transfer of the substance between the reservoir and the biological body. The magnitude, direction and duration of the force are dynamically controlled (e.g., servo-controlled) by the electrical input and can be altered during the course of an actuation cycle. Beneficially, the actuator can be moved in different directions according to the electrical input.Type: GrantFiled: September 18, 2014Date of Patent: April 12, 2016Assignee: Massachusetts Institute of TechnologyInventors: Ian W. Hunter, Andrew J. Taberner, Brian D. Hemond, Dawn M. Wendell, Nora Catherine Hogan, Nathan B. Ball
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Patent number: 9125990Abstract: The present invention relate to a method and corresponding apparatus for just in time mixing of a solid or powdered formulation and its subsequent delivery to a biological body. In some embodiments, a powdered formulation is maintained in a first chamber. A bi-directional electromagnetic actuator is in communication with the chamber. The actuator, when activated, generates a pressure within the first chamber. The pressure results in mixing of the powdered formulation and a diluent in time for delivering into the biological body.Type: GrantFiled: December 3, 2010Date of Patent: September 8, 2015Assignee: Massachusetts Institute of TechnologyInventors: Ian W. Hunter, Andrew J. Taberner, N. Catherine Hogan
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Patent number: 8992466Abstract: A needle-free transdermal transport device for transferring a substance across a surface of a biological body includes a reservoir for storing the substance, a nozzle in fluid communication with the reservoir and a controllable electromagnetic actuator in communication with the reservoir. The actuator, referred to as a Lorentz force actuator, includes a stationary magnet assembly and a moving coil assembly. The coil assembly moves a piston having an end portion positioned within the reservoir. The actuator receives an electrical input and generates in response a corresponding force acting on the piston and causing a needle-free transfer of the substance between the reservoir and the biological body. The magnitude, direction and duration of the force are dynamically controlled (e.g., servo-controlled) by the electrical input and can be altered during the course of an actuation cycle. Beneficially, the actuator can be moved in different directions according to the electrical input.Type: GrantFiled: December 7, 2012Date of Patent: March 31, 2015Assignee: Massachusetts Institute of TechnologyInventors: Ian W. Hunter, Andrew J. Taberner, Brian D. Hemond, Dawn M. Wendell, Nora Catherine Hogan, Nathan B. Ball
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Publication number: 20150025505Abstract: The present invention relate to a method and corresponding apparatus for just in time mixing of a solid or powdered formulation and its subsequent delivery to a biological body. In some embodiments, a powdered formulation is maintained in a first chamber of a plurality of chambers. A plurality of electromagnetic actuators are in communication with the plurality of chambers. The actuators, when activated, generate a pressure within at least the first chamber. The pressure results in mixing of the powdered formulation and a diluent in time for delivering into the biological body.Type: ApplicationFiled: October 2, 2014Publication date: January 22, 2015Inventors: Ian W. Hunter, Andrew J. Taberner, N. Catherine Hogan
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Publication number: 20150005701Abstract: A needle-free transdermal transport device for transferring a substance across a surface of a biological body includes a reservoir for storing the substance, a nozzle in fluid communication with the reservoir and a controllable electromagnetic actuator in communication with the reservoir. The actuator, referred to as a Lorentz force actuator, includes a stationary magnet assembly and a moving coil assembly. The coil assembly moves a piston having an end portion positioned within the reservoir. The actuator receives an electrical input and generates in response a corresponding force acting on the piston and causing a needle-free transfer of the substance between the reservoir and the biological body. The magnitude, direction and duration of the force are dynamically controlled (e.g., servo-controlled) by the electrical input and can be altered during the course of an actuation cycle. Beneficially, the actuator can be moved in different directions according to the electrical input.Type: ApplicationFiled: September 18, 2014Publication date: January 1, 2015Inventors: Ian W. Hunter, Andrew J. Taberner, Brian D. Hemond, Dawn M. Wendell, Nora Catherine Hogan, Nathan B. Ball
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Publication number: 20140257236Abstract: A method for injecting a substance through a biological body surface includes providing a needle-free transdermal transport device configured to inject the substance through the surface. The substance is injected into the biological body with the transport device while a parameter of the injection is sensed and a servo-controller is used to dynamically adjust at least one injection characteristic based on the sensed parameter. The substance is injected for (i) a first time period during which a first portion of a volume of the substance is injected at a first injection pressure, and (ii) a second time period during which a remainder of the volume of the substance is injected at a second injection pressure. A viscosity of the substance may be determined, and a pressure calculated for injecting the substance based on the viscosity. The substance may be injected with the transport device by using the calculated pressure.Type: ApplicationFiled: May 16, 2014Publication date: September 11, 2014Applicant: Massachusetts Institute of TechnologyInventors: Brian D. Hemond, Ian W. Hunter, Andrew J. Taberner, Dawn M. Wendell, N. Catherine Hogan
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Patent number: 8821434Abstract: A method for transferring a solid body across a surface of a biological body includes (i) applying an electrical input to a controllable electromagnetic actuator; (ii) producing with the electromagnetic actuator a mechanical force corresponding to the electrical input; and (iii) applying the mechanical force to a reservoir coupled at one end to a nozzle, the mechanical force producing a pressure within the reservoir, a magnitude of the pressure varying with the mechanical force and causing ejection of a fluid from the reservoir to drive the solid body into the biological body. A method for delivering a substance to a target body includes (i) positioning a needle-free injector proximate to a surface of the target body; (ii) injecting the substance into the target body; and (iii) while injecting, moving the needle-free injector along the surface, thereby sweeping the surface.Type: GrantFiled: October 7, 2011Date of Patent: September 2, 2014Assignee: Massachusetts Institute Of TechnologyInventors: Ian W. Hunter, Andrew J. Taberner, N. Catherine Hogan
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Patent number: 8740838Abstract: A method for injecting a substance through a biological body surface includes providing a needle-free transdermal transport device configured to inject the substance through the surface. The substance is injected into the biological body with the transport device while a parameter of the injection is sensed and a servo-controller is used to dynamically adjust at least one injection characteristic based on the sensed parameter. The substance is injected for (i) a first time period during which a first portion of a volume of the substance is injected at a first injection pressure, and (ii) a second time period during which a remainder of the volume of the substance is injected at a second injection pressure. A viscosity of the substance may be determined, and a pressure calculated for injecting the substance based on the viscosity. The substance may be injected with the transport device by using the calculated pressure.Type: GrantFiled: October 7, 2011Date of Patent: June 3, 2014Assignee: Massachusetts Institute of TechnologyInventors: Brian D. Hemond, Ian W. Hunter, Andrew J. Taberner, Dawn M. Wendell, N. Catherine Hogan
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Patent number: 8398583Abstract: The present invention relate to a method and corresponding apparatus for extraction of a sample from a sample source. A fluid is injected into the sample source and the sample source is vibrated. A sample is withdrawn from the vibrated sample source and the sample source is evaluated by measuring one or more identifying parameters in the withdrawn sample.Type: GrantFiled: September 10, 2010Date of Patent: March 19, 2013Assignee: Massachusetts Institute of TechnologyInventors: Ian W. Hunter, Andrew J. Taberner, N. Catherine Hogan
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Patent number: 8328755Abstract: A needle-free transdermal transport device for transferring a substance across a surface of a biological body includes a reservoir for storing the substance, a nozzle in fluid communication with the reservoir and a controllable electromagnetic actuator in communication with the reservoir. The actuator, referred to as a Lorentz force actuator, includes a stationary magnet assembly and a moving coil assembly. The coil assembly moves a piston having an end portion positioned within the reservoir. The actuator receives an electrical input and generates in response a corresponding force acting on the piston and causing a needle-free transfer of the substance between the reservoir and the biological body. The magnitude, direction and duration of the force are dynamically controlled (e.g., servo-controlled) by the electrical input and can be altered during the course of an actuation cycle. Beneficially, the actuator can be moved in different directions according to the electrical input.Type: GrantFiled: October 18, 2010Date of Patent: December 11, 2012Assignee: Massachusetts Institute of TechnologyInventors: Ian W. Hunter, Andrew J. Taberner, Brian D. Hemond, Dawn M. Wendell, Nora Catherine Hogan, Nathan B. Ball
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Patent number: 8172790Abstract: A needle-free transdermal transport device includes a chamber (900) for holding the substance to be injected, a nozzle (910) in fluid communication with the chamber, and a drug reservoir (950) for storing the substance to be transferred to the chamber. The needle-free transdermal transport device also includes a controllable magnet and coil electromagnetic actuator (242) in communication with the chamber. The actuator receives an electrical input and generates in response a force. The force then causes a needle-free transfer of the substance from the chamber to the biological body. The force is variable responsive to variations in the received input during actuation. The actuator draws the substance from the drug reservoir or alternatively, the substance can be pressurized from the drug reservoir into the chamber by a pressure source.Type: GrantFiled: August 31, 2007Date of Patent: May 8, 2012Assignee: Massachusetts Institute of TechnologyInventors: Ian W. Hunter, Brian D. Hemond, Dawn M. Wendell, Nora Catherine Hogan, Andrew J. Taberner, Nathan B. Ball
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Publication number: 20120095435Abstract: A method for transferring a solid body across a surface of a biological body includes (i) applying an electrical input to a controllable electromagnetic actuator; (ii) producing with the electromagnetic actuator a mechanical force corresponding to the electrical input; and (iii) applying the mechanical force to a reservoir coupled at one end to a nozzle, the mechanical force producing a pressure within the reservoir, a magnitude of the pressure varying with the mechanical force and causing ejection of a fluid from the reservoir to drive the solid body into the biological body. A method for delivering a substance to a target body includes (i) positioning a needle-free injector proximate to a surface of the target body; (ii) injecting the substance into the target body; and (iii) while injecting, moving the needle-free injector along the surface, thereby sweeping the surface.Type: ApplicationFiled: October 7, 2011Publication date: April 19, 2012Applicant: Massachusetts Institute of TechnologyInventors: Ian W. Hunter, Andrew J. Taberner, N. Catherine Hogan