Abstract: Systems and methods of handling customer contacts at a customer care system that streamline the handling of such customer contacts based on information about previous contacts received from the same customers. The system includes a repeat contact engine, which is connectable to at least one data/communications network. The repeat contact engine includes a controller, at least one database communicably connected to the controller, and a data extractor communicably connected between the data/communications network and the database. The controller includes a server, a rule processor communicably connected to the server, and a policy engine associated with the rule processor. Based on information about at least one previous contact, the system can derive a rule that, in response to its application, would cause a predetermined response, representative of the predicted purpose of an incoming contact, to be provided over a corresponding channel through the data/communications network.

Abstract: Systems and methods of handling customer contacts at a customer care system that streamline the handling of such customer contacts based on information about previous contacts received from the same customers. The system includes a repeat contact engine, which is connectable to at least one data/communications network. The repeat contact engine includes a controller, at least one database communicably connected to the controller, and a data extractor communicably connected between the data/communications network and the database. The controller includes a server, a rule processor communicably connected to the server, and a policy engine associated with the rule processor. Based on information about at least one previous contact, the system can derive a rule that, in response to its application, would cause a predetermined response, representative of the predicted purpose of an incoming contact, to be provided over a corresponding channel through the data/communications network.

Abstract: The present invention provides novel polynucleotides encoding K+betaM3 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel K+betaM3 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

Abstract: Dual inhibitors of PDE7 and PDE4, together with their use to treat leukocyte activation-associated disorders (including transplant rejection, rheumatoid arthritis, inflammatory bowel disease, psoriasis, asthma, chronic obstructive pulmonary disease, lupus and multiple sclerosis), are provided herein.

Abstract: Peptide sequences are disclosed which immunologically mimic proteins encoded by the env and gag regions of LAV-2, a retrovirus associated with AIDS. The peptide can be used in various specific binding assays to detect the presence of antibodies to LAV-2 in individuals previously exposed to the virus. The peptides enable one to distinguish the presence of antibodies to LAV-2 from antibodies to HIV-1.