Abstract: A system and method for operation of an autonomous vehicle (AV) yard truck is provided. A processor facilitates autonomous movement of the AV yard truck, and connection to and disconnection from trailers. A plurality of sensors are interconnected with the processor that sense terrain/objects and assist in automatically connecting/disconnecting trailers. A server, interconnected, wirelessly with the processor, that tracks movement of the truck around and determines locations for trailer connection and disconnection. A door station unlatches/opens rear doors of the trailer when adjacent thereto, securing them in an opened position via clamps, etc. The system computes a height of the trailer, and/or if landing gear of the trailer is on the ground and interoperates with the fifth wheel to change height, and whether docking is safe, allowing a user to take manual control, and optimum charge time(s). Reversing sensors/safety, automated chocking, and intermodal container organization are also provided.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for performing protein design. In one aspect, a method comprises: processing an input characterizing a target protein structure of a target protein using an embedding neural network having a plurality of embedding neural network parameters to generate an embedding of the target protein structure of the target protein; determining a predicted amino acid sequence of the target protein based on the embedding of the target protein structure, comprising: conditioning a generative neural network having a plurality of generative neural network parameters on the embedding of the target protein structure; and generating, by the generative neural network conditioned on the embedding of the target protein structure, a representation of the predicted amino acid sequence of the target protein.

Abstract: A patient interface including a positioning and stabilizing structure that is configured to maintain a first seal-forming structure and a second seal-forming structure in a therapeutically effective position. The positioning and stabilizing structure comprises a frame coupled to the plenum chamber. The frame includes a central portion coupled to the plenum chamber outside of the cavity. The frame also includes a pair of arms that extend away from the central portion in a posterior direction past the second seal-forming structure. The pair of arms are more flexible than the central portion. The positioning and stabilizing structure also includes headgear straps coupled to the frame, which configured to provide a tensile force to the first seal-forming structure and to the second seal-forming structure into the patient's face via the frame.

Abstract: A patient interface may include a plenum chamber and a positioning and stabilising structure. The plenum chamber may include a seal-forming structure and a fascia portion. At least a medial portion of the fascia portion is flexible. In embodiments, the patient interface may include a rigidiser to control flexing of the fascia portion.

Abstract: A patient interface includes a frame assembly including connectors operatively attachable to headgear, a cushion assembly provided to the frame assembly and including a seal-forming structure structured to form a seal with the patient's nose and/or mouth, and an air delivery connector provided to the frame assembly and operatively connected to an air delivery tube for supplying the air at positive pressure along an air flow path. The cushion assembly is structured to releasably connect to the frame assembly independently of the air delivery connector. The air delivery connector is structured to releasably connect to the frame assembly independently of the cushion assembly.

Abstract: A patient interface comprises a plenum chamber and a seal-forming structure. The seal-forming structure comprises a support structure arranged to support a sealing portion that is adapted to sealing engage the patient's face in use. The seal-forming structure may also include a seal biasing portion configured to inflate under pressurization within the cavity in the cushion assembly in use to extend the reach of the sealing portion and decouple the sealing portion from external forces.

Abstract: A patient interface is configured to deliver a flow of positive pressure respiratory gas to an entrance of a patients airways. The patient interface includes an elastomeric support wall forming at least part of a plenum chamber configured to receive the flow of positive pressure respiratory gas. The patient interface also includes an elastomeric support flange positioned at an end of the elastomeric support wall and extending radially inward from the support wall. The support flange has a flap portion at a central superior region of the support flange that extends further in the radially inward direction than the rest of the support flange. In addition, a foam cushion is mounted on the support flange. The foam cushion is configured to form a seal with the patients face and includes an attachment surface that is in contact with an outer surface of the support flange.

Abstract: A patient interface comprises a plenum chamber and a seal-forming structure. The seal-forming structure comprises a support structure arranged to support a sealing portion that is adapted to sealing engage the patient's face in use. The seal-forming structure may also include a seal biasing portion configured to inflate under pressurization within the cavity in the cushion assembly in use to extend the reach of the sealing portion and decouple the sealing portion from external forces.

Abstract: A patient interface including a positioning and stabilizing structure that is configured to maintain a first seal-forming structure and a second seal-forming structure in a therapeutically effective position. The positioning and stabilizing structure comprises a frame coupled to the plenum chamber. The frame includes a central portion coupled to the plenum chamber outside of the cavity. The frame also includes a pair of arms that extend away from the central portion in a posterior direction past the second seal-forming structure. The pair of arms are more flexible than the central portion. The positioning and stabilizing structure also includes headgear straps coupled to the frame, which configured to provide a tensile force to the first seal-forming structure and to the second seal-forming structure into the patient's face via the frame.

Abstract: A patient interface may include a plenum chamber and a positioning and stabilising structure. The plenum chamber may include a seal-forming structure and a fascia portion. At least a medial portion of the fascia portion is flexible. In embodiments, the patient interface may include a rigidiser to control flexing of the fascia portion.

Abstract: A patient interface includes a frame assembly including connectors operatively attachable to headgear, a cushion assembly provided to the frame assembly and including a seal-forming structure structured to form a seal with the patient's nose and/or mouth, and an air delivery connector provided to the frame assembly and operatively connected to an air delivery tube for supplying the air at positive pressure along an air flow path. The cushion assembly is structured to releasably connect to the frame assembly independently of the air delivery connector. The air delivery connector is structured to releasably connect to the frame assembly independently of the cushion assembly.

Abstract: A patient interface comprises a plenum chamber and a seal-forming structure. The seal-forming structure comprises a support structure arranged to support a sealing portion that is adapted to sealing engage the patient's face in use. The seal-forming structure may also include a seal biasing portion configured to inflate under pressurization within the cavity in the cushion assembly in use to extend the reach of the sealing portion and decouple the sealing portion from external forces.

Abstract: A patient interface includes a frame assembly (16100) including connectors operatively attachable to headgear, a cushion assembly (16175) including a shell (161800) and a seal-forming structure (16200) structured to form a seal with the patient's nose and/or mouth, and an air delivery connector (16600). The cushion assembly and air delivery connector are structured to releasably connect to the frame assembly independently of each other. A static face seal and separate static diametric seal between the shell (161800) and frame (16100). A dynamic face seal and separate dynamic diametric seal between the air delivery connector (16600) and frame (16100). Separate claims (FIG. 6) to a frame assembly (16100) with upper headgear connector arms (16134) including at least one slot (6146) (claim 17) or flexible portions (claim 22) to form hinges structured and arranged to conform to varying facial profiles.

Abstract: A method of planning a coverage path to cover an area. The method includes a computing arrangement iteratively receiving, generating and displaying. The computing arrangement is configured to receive a range acceptable user-inputs. The receiving includes receiving user-input within the range of acceptable user-inputs. The generating includes generating a feasible coverage path based on the user-input. The displaying includes displaying at least some detail of the feasible coverage path.

Abstract: A patient interface includes a frame assembly (16100) including connectors operatively attachable to headgear, a cushion assembly (16175) including a shell (161800) and a seal-forming structure (16200) structured to form a seal with the patient's nose and/or mouth, and an air delivery connector (16600). The cushion assembly and air delivery connector are structured to releasably connect to the frame assembly independently of each other. A static face seal and separate static diametric seal between the shell (161800) and frame (16100). A dynamic face seal and separate dynamic diametric seal between the air delivery connector (16600) and frame (16100). Separate claims (FIG. 6) to a frame assembly (16100) with upper headgear connector arms (16134) including at least one slot (6146) (claim 17) or flexible portions (claim 22) to form hinges structured and arranged to conform to varying facial profiles.

Abstract: A long-range viewing apparatus is described, the long-range viewing apparatus arranged to provide an all-in-one solution to combining two videos streams obtained coaxially through a single imaging aperture. A long-range viewing apparatus comprising, a housing; a first camera within the housing; a second camera within the housing; and a processing element; wherein the processing element is arranged to combine images from the first and second cameras; wherein the processing element is further arranged to scale images from the first and second cameras; wherein the processing element is further arranged to crop images from the first and second cameras; characterised in that, the first camera is positioned coaxially in front of the second camera; and the housing comprises a single imaging aperture. The invention aims to achieve real-time digital foveal zoom capabilities in a physically robust, low-weight, low-complexity and small form factor assembly suitable for demanding applications.