Patents by Inventor Andrew James Rutter

Andrew James Rutter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Monitoring oligonucleotide binding processes using chemiluminescence quenching
    Patent number: 7169554
    Abstract: Oligonucleotide building processes are monitored by means of an oligonucleotide probe which in one embodiment is labelled at one end with a chemiluminescent label and at the other end with a quencher molecule. The conformation of the oligonucleotide probe changes according to whether the probe hybridises with a substantially complementary nucleic acid sequence. In the non-hybridised state the chemiluminescent label is sufficiently close proximity to the quencher that the chemiluminescent emission is substantially attenuated, but in the hybridised state the separation is such that there is little or no attenuation. Particular probes and emitter/quencher pairs are disclosed.
    Type: Grant
    Filed: December 11, 2000
    Date of Patent: January 30, 2007
    Assignee: Gen-Probe Incorporated
    Inventors: Andrew James Rutter, Ian Weeks, Zhaoqiang Li, Keith Smith
  • Monitoring oligonucleotide binding processes using chemiluminescence quenching
    Publication number: 20030082713
    Abstract: Oligonucleotide building processes are monitored by means of an oligonucleotide probe which in one embodiment is labelled at one end with a chemiluminescent label and at the other end with a quencher molecule. The conformation of the oligonucleotide probe changes according to whether the probe hybridises with a substantially complementary nucleic acid sequence. In the non-hybridised state the chemiluminescent label is sufficiently close proximity to the quencher that the chemiluminescent emission is substantially attenuated, but in the hybridised state the separation is such that there is little or no attenuation. Particular probes and emitter/quencher pairs are disclosed.
    Type: Application
    Filed: August 12, 2002
    Publication date: May 1, 2003
    Inventors: Andrew James Rutter, Ian Weeks, Zhaoqiang Li, Keith Smith