Abstract: The present disclosure provides compounds of Formula I, Ia, Ib, Ib-1, Ib-2, Ic, Ic-1, Id-1, and Id-2. Compounds of Formula I, Ia, Ib, Ib-1, Ib-2, Ic, Ic-1, Id-1, and Id-2 may be used in pharmaceutical formulations, and may be used for modulating glucocorticoid receptors.

Abstract: The present disclosure provides compounds of Formula I, Ia, Ib, Ib-1, Ib-2, Ic, Ic-1, Id-1, and Id-2. Compounds of Formula I, Ia, Ib, Ib-1, Ib-2, Ic, Ic-1, Id-1, and Id-2 may be used in pharmaceutical formulations, and may be used for modulating glucocorticoid receptors.

Abstract: According to an aspect of the invention, there is provided a control system for controlling a projectile, the control system comprising: a plurality of transmitters, wherein each transmitter of the plurality of transmitters is arranged to transmit an electromagnetic wave from a transmission position; a receiver associated with the projectile, the receiver being arranged to receive a plurality of electromagnetic waves transmitted from the plurality of transmitters; a controller associated with the projectile, the controller being arranged to: determine at least one of a position, a velocity or an acceleration of the projectile from transmission positions of the plurality of transmitters and Doppler measurements derived from the received plurality of electromagnetic waves; and generate a control signal for performing an action with the projectile depending on the determined at least one of position, velocity or acceleration of the projectile.

Abstract: The present disclosure provides compounds of Formula I, Ia, Ib, Ib-1, Ib-2, Ic, Ic-1, Id-1, and Id-2. Compounds of Formula I, Ia, Ib, Ib-1, Ib-2, Ic, Ic-1, Id-1, and Id-2 may be used in pharmaceutical formulations, and may be used for modulating glucocorticoid receptors.

Abstract: Video cyclic sexual movement detection and synchronisation apparatus (10) includes a selector (12), an analyser (14) and a output generator (16). In use, the apparatus (10) receives an input signal (18) which comprises a sequence (94) of video frames (20), each frame (20) comprising a plurality of image areas (22). In a selection phase, the selector (12) selects one of the image areas (22) as a subject area (24) and another of the image areas (22) as a reference area 26. In an analysis phase, the analyser (14) analyses a set (28) of the video frames (20) to determine a subject speed parameter (30) which relates to the speed of movement of the subject area (24) relative to the reference area (26). In a synchronisation phase, the output generator (16) generates an output signal (38) which comprises a speed signal (40) which is dependent on the subject speed parameter (30).

Abstract: The present invention provides organic compounds which are capable of releasing carbon monoxide under physiological conditions or pH trigger, and to the use of such compounds for conditioning a cell, tissue or organ, for example, to protect against ischaemic injury during a transplant event.

Abstract: The present invention provides organic compounds which are capable of releasing carbon monoxide under physiological conditions or pH trigger, and to the use of such compounds for conditioning a cell, tissue or organ, for example, to protect against ischaemic injury during a transplant event.

Abstract: The present invention provides organic compounds which are capable of releasing carbon monoxide under physiological conditions or pH trigger, and to the use of such compounds for conditioning a cell, tissue or organ, for example, to protect against ischaemic injury during a transplant event.

Abstract: According to an aspect of the invention, there is provided a control system for controlling a projectile, the control system comprising: a plurality of transmitters, wherein each transmitter of the plurality of transmitters is arranged to transmit an electromagnetic wave from a transmission position; a receiver associated with the projectile, the receiver being arranged to receive a plurality of electromagnetic waves transmitted from the plurality of transmitters; a controller associated with the projectile, the controller being arranged to: determine at least one of a position, a velocity or an acceleration of the projectile from transmission positions of the plurality of transmitters and Doppler measurements derived from the received plurality of electromagnetic waves; and generate a control signal for performing an action with the projectile depending on the determined at least one of position, velocity or acceleration of the projectile.

Abstract: According to an aspect of the present disclosure, a stimulator apparatus is configured for providing stimulation to a human or animal body. In some embodiments, the stimulator apparatus includes a control housing; an electrical power source; contact connection; an object sensor within the control housing adapted to detect at least one control feature of proximity, gesture, movement and colour of an object and/or body part within a motion detection distance range of the control housing; and control circuit means adapted to distinguish the control feature or features of the object or body part in order to vary one or more stimulating parameters of the electrical output of the stimulator apparatus.

Abstract: Tents and canopies are ubiquitous for outdoor recreation and gatherings. Tents and canopies are poorly lit, especially during night time. Camping lights such as lanterns are ineffective for lighting the entire space of a tent or canopy. To address these issues, a lighting apparatus can improve the quality of lighting inside a tent or a canopy by lighting a tent using a plurality of flexible strips having lighting elements thereon and providing a housing enclosing a lighting controller circuit for controlling the lighting elements. The flexible strips are electrically coupled to the lighting controller and extends away from the lighting controller. The housing can be hung inside, near the top center point of the tent or canopy to illuminate not only the area inside the tent or canopy, but also the tent or canopy itself. The lighting apparatus has a unique physical design suited for tents, canopies, and automobiles.

Abstract: The present invention provides organic compounds which are capable of releasing carbon monoxide under physiological conditions or pH trigger, and to the use of such compounds for conditioning a cell, tissue or organ, for example, to protect against ischaemic injury during a transplant event.

Abstract: Tents and canopies are ubiquitous for outdoor recreation and gatherings. Tents and canopies are poorly lit, especially during night time. Camping lights such as lanterns are ineffective for lighting the entire space of a tent or canopy. To address these issues, a lighting apparatus can improve the quality of lighting inside a tent or a canopy by lighting a tent using a plurality of flexible strips having lighting elements thereon and providing a housing enclosing a lighting controller circuit for controlling the lighting elements. The flexible strips are electrically coupled to the lighting controller and extends away from the lighting controller. The housing can be hung inside, near the top center point of the tent or canopy to illuminate not only the area inside the tent or canopy, but also the tent or canopy itself. The lighting apparatus has a unique physical design suited for tents, canopies, and automobiles.

Abstract: The invention relates to compounds having Formula (1): A-L-B or pharmaceutically acceptable salts thereof, wherein: A is a dicarbonyl sequestering moiety comprising a substituted aryl group or a substituted heteroaryl group; L is an optional linker moiety; and B is a mitochondrial targeting moiety. The invention also relates to pharmaceutical compositions containing such compounds and salts, and to the use of such compounds and salts for treating diabetes, preferably hyperglycemic diabetes. A mass spectrometry probe and to a method of labelling a biological molecule 1 for mass spectrometry detection are also described.

Abstract: Methods and apparatus for controlling a bias voltage (20) supplied to an optical modulator that comprises a biasable component configurable to be biased by application of the bias voltage (20), the method comprising: providing a target for the modulator output power; applying, to the biasable component, a bias voltage (20) that biases the biasable component so that the output power is within a pre-defined range of the target; monitoring the output power and, if the output power of the modulator is determined to be outside the pre-defined range, varying the value of the bias voltage (20) to bring the output power back within the pre-defined range; and monitoring the optical input to the modulator and, if it has been disabled, maintaining the bias voltage (20) at its current level for a pre-determined length of time that is dependent upon how long the modulator has been operating at quadrature.

Abstract: An optical signal transmission apparatus (1) for a rotating antenna comprising a plurality of optical modulators (6) arranged for receiving a respective plurality of analog RF signals (5) and for modulating a respective plurality of optical signals therewith to produce a plurality of modulated analog optical signals (8). A plurality of opto-electrical converters (14) each converts a respective modulated analog optical signal (13) into an analog electrical signal. The plurality of optical modulators (6) are rotationally coupled in optical communication with the plurality of opto-electrical converters (14) via an optical rotary joint (10) including a reversion prism.

Abstract: The invention relates to novel NO donors which are targeted to the mitochondria. The NO donor compounds of the invention allow NO to be selectively provided to the mitochondria.

Abstract: Methods and apparatus for controlling a bias voltage supplied to an optical modulator, the modulator comprising a biasable component, the biasable component being configurable to be biased by application of the bias voltage (20) such that the modulator operates at quadrature, the method comprising: providing a target for the output power of the modulator, the target for the output power of the modulator being an output power corresponding to the modulator operating at quadrature; applying, to the biasable component, a bias voltage (20) having an initial value of 0V; and, thereafter, varying the bias voltage (20) until the value of the bias voltage (20) is the value that is closest to the initial value and that biases the biasable component so that the output power of the modulator is within a pre-defined range of the target output power.

Abstract: The invention relates to novel NO donors which are targeted to the mitochondria. The NO donor compounds of the invention allow NO to be selectively provided to the mitochondria.