Patents by Inventor Andrew Janoff

Andrew Janoff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions for delivery of drug combinations
    Patent number: 10722464
    Abstract: Compositions which comprise delivery vehicles having stably associated therewith non-antagonistic combinations of two or more agents, such as antineoplastic agents, are useful in achieving non-antagonistic effects when combinations of drugs are administered.
    Type: Grant
    Filed: July 27, 2018
    Date of Patent: July 28, 2020
    Assignee: Celator Pharmaceuticals, Inc.
    Inventors: Paul Tardi, Troy Harasym, Murray Webb, Clifford Shew, Andrew Janoff, Lawrence Mayer, Marcel Bally
  • COMPOSITIONS FOR DELIVERY OF DRUG COMBINATIONS
    Publication number: 20180338917
    Abstract: Compositions which comprise delivery vehicles having stably associated therewith non-antagonistic combinations of two or more agents, such as antineoplastic agents, are useful in achieving non-antagonistic effects when combinations of drugs are administered.
    Type: Application
    Filed: July 27, 2018
    Publication date: November 29, 2018
    Inventors: Paul TARDI, Troy HARASYM, Murray WEBB, Clifford SHEW, Andrew JANOFF, Lawrence MAYER, Marcel BALLY
  • Compositions for delivery of drug combinations
    Patent number: 10058507
    Abstract: Compositions which comprise delivery vehicles having stably associated therewith non-antagonistic combinations of two or more agents, such as antineoplastic agents, are useful in achieving non-antagonistic effects when combinations of drugs are administered.
    Type: Grant
    Filed: January 7, 2016
    Date of Patent: August 28, 2018
    Assignee: CELATOR PHARMACEUTICALS, INC.
    Inventors: Paul Tardi, Troy Harasym, Murray Webb, Clifford Shew, Andrew Janoff, Lawrence Mayer, Marcel Bally
  • COMPOSITIONS FOR DELIVERY OF DRUG COMBINATIONS
    Publication number: 20160113871
    Abstract: Compositions which comprise delivery vehicles having stably associated therewith non-antagonistic combinations of two or more agents, such as antineoplastic agents, are useful in achieving non-antagonistic effects when combinations of drugs are administered.
    Type: Application
    Filed: January 7, 2016
    Publication date: April 28, 2016
    Applicant: CELATOR PHARMACEUTICALS, INC.
    Inventors: Paul Tardi, Troy Harasym, Murray Webb, Clifford Shew, Andrew Janoff, Lawrence Mayer, Marcel Bally
  • Compositions for delivery of drug combinations
    Patent number: 9271931
    Abstract: Compositions which comprise delivery vehicles having stably associated therewith non-antagonistic combinations of two or more agents, such as antineoplastic agents, are useful in achieving non-antagonistic effects when combinations of drugs are administered.
    Type: Grant
    Filed: April 16, 2004
    Date of Patent: March 1, 2016
    Assignee: CELATOR PHARMACEUTICALS, INC.
    Inventors: Paul Tardi, Troy Harasym, Murray Webb, Clifford Shew, Lawrence Mayer, Andrew Janoff, Marcel Bally
  • Fixed drug ratios for treatment of hematopoietic cancers and proliferative disorders
    Patent number: 8092828
    Abstract: Provided herein are methods for treating cancer by administering a pharmaceutical composition comprising a fixed, non-antagonistic molar ratio of cytarabine and an anthracycline. Such methods are particularly useful in the treatment of patients with advanced hematologic cancers or proliferative disorders.
    Type: Grant
    Filed: February 15, 2008
    Date of Patent: January 10, 2012
    Assignee: Celator Pharmaceuticals, Inc.
    Inventors: Arthur Louie, Christine Swenson, Lawrence Mayer, Andrew Janoff
  • Compositions for delivery of drug combinations
    Patent number: 7850990
    Abstract: Compositions which comprise delivery vehicles having stably associated therewith non-antagonistic combinations of two or more agents, such as antineoplastic agents, are useful in achieving non-antagonistic effects when combinations of drugs are administered.
    Type: Grant
    Filed: April 16, 2003
    Date of Patent: December 14, 2010
    Assignee: Celator Pharmaceuticals, Inc.
    Inventors: Paul Tardi, Troy Harasym, Murray Webb, Clifford Shew, Marcel Bally, Lawrence Mayer, Andrew Janoff
  • FIXED DRUG RATIOS FOR TREATMENT OF HEMATOPOIETIC CANCERS AND PROLIFERATIVE DISORDERS
    Publication number: 20100303895
    Abstract: Provided herein are methods for treating cancer by administering a pharmaceutical composition comprising a fixed, non-antagonistic molar ratio of cytarabine and an anthracycline. Such methods are particularly useful in the treatment of patients with advanced hematologic cancers or proliferative disorders.
    Type: Application
    Filed: February 15, 2008
    Publication date: December 2, 2010
    Inventors: Arthur Louie, Christine Swenson, Lawrence Mayer, Andrew Janoff
  • Fixed ratio drug combination treatments for solid tumors
    Patent number: 7842676
    Abstract: Provided herein are methods for treating cancer by administering a pharmaceutical composition comprising a fixed, non-antagonistic molar ratio of irinotecan and floxuridine. Such methods are particularly useful in the treatment of cancer patients with advanced solid tumors.
    Type: Grant
    Filed: October 25, 2006
    Date of Patent: November 30, 2010
    Assignee: Celator Pharmaceuticals, Inc.
    Inventors: Andrew Janoff, Lawrence Mayer, John Redman, Christine Swenson
  • FIXED RATIO DRUG COMBINATION TREATMENTS FOR SOLID TUMORS
    Publication number: 20100189771
    Abstract: Provided herein are methods for treating cancer by administering a pharmaceutical composition comprising a fixed, non-antagonistic molar ratio of irinotecan and floxuridine. Such methods are particularly useful in the treatment of cancer patients with advanced solid tumors.
    Type: Application
    Filed: October 25, 2006
    Publication date: July 29, 2010
    Inventors: Lawrence Mayer, Christine Swenson, Andrew Janoff, John Redman
  • Encapsulation of Bioactive Complexes in Liposomes
    Publication number: 20090068256
    Abstract: This invention provides a method to prepare liposome-encapsulated bioactive agents, such as nucleic acids, comprising complexation of the bioactive agents to reverse micelles prior to forming liposomes, as well as methods of using the liposomes so formed and formulations to deliver nucleic acids to cells.
    Type: Application
    Filed: August 25, 2008
    Publication date: March 12, 2009
    Inventors: Paul Meers, Tong Shangguan, Donna Cabral-Lilly, Andrew Janoff, Patrick Ahl
  • Fixed ratio drug combination treatments for solid tumors
    Publication number: 20090023680
    Abstract: Provided herein are methods for treating cancer by administering a pharmaceutical composition comprising a fixed, non-antagonistic molar ratio of irinotecan and floxuridine. Such methods are particularly useful in the treatment of cancer patients with advanced solid tumors.
    Type: Application
    Filed: October 25, 2006
    Publication date: January 22, 2009
    Inventors: Andrew Janoff, Lawrence Mayer, John Redman, Gerald Batist, Christine Swenson, Karen Gelmon
  • FIXED DRUG RATIOS FOR TREATMENT OF HEMATOPOIETIC CANCERS AND PROLIFERATIVE DISORDERS
    Publication number: 20080199515
    Abstract: Provided herein are methods for treating cancer by administering a pharmaceutical composition comprising a fixed, non-antagonistic molar ratio of cytarabine and an anthracycline. Such methods are particularly useful in the treatment of patients with advanced hematologic cancers or proliferative disorders.
    Type: Application
    Filed: February 15, 2008
    Publication date: August 21, 2008
    Inventors: Arthur Louie, Christine Swenson, Lawrence Mayer, Andrew Janoff
  • Compositions for Delivery of Drug Combinations
    Publication number: 20070298092
    Abstract: Compositions which comprise delivery vehicles having stably associated therewith non-antagonistic combinations of two or more agents, such as antineoplastic agents, are useful in achieving non-antagonistic effects when combinations of drugs are administered.
    Type: Application
    Filed: April 16, 2004
    Publication date: December 27, 2007
    Inventors: Paul Tardi, Troy Harasym, Murray Webb, Clifford Shew, Lawrence Mayer, Andrew Janoff
  • Compositions for delivery of drug combinations
    Publication number: 20070148255
    Abstract: Methods to prepare compositions which comprise delivery vehicles having stably associated therewith non-antagonistic combinations of two or more agents. The compositions exhibit non-antagonistic effects when combinations of drugs are administered.
    Type: Application
    Filed: January 31, 2007
    Publication date: June 28, 2007
    Inventors: Paul Tardi, Troy Harasym, Murray Webb, Clifford Shew, Marcel Bally, Lawrence Mayer, Andrew Janoff, Trevor Shew, Dominic Shew
  • Methods to individualize combination therapy
    Publication number: 20060228694
    Abstract: Compositions which comprise delivery vehicles having stably associated therewith predetermined, patient-specific combinations of two or more agents, such as antineoplastic agents, are useful in achieving optimal therapeutic effects on a patient-by-patient basis when combinations of drugs are administered.
    Type: Application
    Filed: April 2, 2004
    Publication date: October 12, 2006
    Inventors: Andrew Janoff, Lawrence Mayer
  • Modular targeted liposomal delivery system
    Publication number: 20060172003
    Abstract: A liposome including a fusogenic liposome, a linking moiety and a targeting moiety. The fusogenic liposome is a lipid bilayer encapsulating contents. The linking moiety is electrostatically bound to the lipid bilayer, and the targeting moiety is covalently bound to the linking moiety. The liposome may also include a stabilizing moiety interposed between the linking and targeting moieties, and covalently bound to both. Alternatively, the stabilizing and targeting moieties may be covalently bound to separate linking moieties, the linking moieties being electrostatically bound to the lipid bilayer.
    Type: Application
    Filed: February 22, 2006
    Publication date: August 3, 2006
    Applicant: Transave, Inc.
    Inventors: Paul Meers, Tong Shangguan, Donna Cabral-Lilly, Patrick Ahl, Ravi Erukulla, Andrew Janoff
  • Compositions for delivery of drug combinations
    Publication number: 20060165771
    Abstract: Compositions which comprise delivery vehicles having stably associated therewith non-antagonistic combinations of two or more agents, such as antineoplastic agents, are useful in achieving non-antagonistic effects when combinations of drugs are administered.
    Type: Application
    Filed: December 14, 2005
    Publication date: July 27, 2006
    Inventors: Paul Tardi, Clifford Shew, Andrew Janoff, Lawrence Mayer, Marcel Bally, Dominic Shew, Trevor Shew
  • Modular targeted liposomal delivery system
    Patent number: 7060291
    Abstract: A liposome including a fusogenic liposome, a linking moiety and a targeting moiety. The fusogenic liposome is a lipid bilayer encapsulating contents. The linking moiety is electrostatically bound to the lipid bilayer, and the targeting moiety is covalently bound to the linking moiety. The liposome may also include a stabilizing moiety interposed between the linking and targeting moieties, and covalently bound to both. Alternatively, the stabilizing and targeting moieties may be covalently bound to separate linking moieties, the linking moieties being electrostatically bound to the lipid bilayer.
    Type: Grant
    Filed: November 17, 2000
    Date of Patent: June 13, 2006
    Assignee: Transave, Inc.
    Inventors: Paul R. Meers, Tong Shangguan, Donna Cabral-Lilly, Patrick Ahl, Ravi Erukulla, Andrew Janoff
  • D and L etherlipid stereoisomers and liposomes
    Publication number: 20040047903
    Abstract: A liposome having a lipid bilayer, where the lipid bilayer includes either the L or D stereoisomer of an ether lipid or a non-equal mixture of both. Most preferably the liposome also comprises (a) an underivatized phosphatidylcholine; (b) a sterol; (c) about 5-20 mole % of a phosphatidylethanolamine linked to a dicarboxylic acid at the ethanolamine group of the phosphatidylethanolamine, and (d) greater than about 10 mole % to less than about 30 mole % of either the L or D stereoisomer of an ether lipid. The liposome may be used as an anti-cancer or anti-inflammatory agent.
    Type: Application
    Filed: August 26, 2003
    Publication date: March 11, 2004
    Applicant: ELAN PHARMACEUTICALS, INC.
    Inventors: Imran Ahmed, Eric Mayhew, Andrew Janoff