Abstract: The disclosure relates to therapeutic proteins and pharmaceutical compositions comprising said proteins, which have utility in treating various human diseases. In particular aspects, the disclosed therapeutic proteins are useful for treating human gastrointestinal inflammatory diseases and gastrointestinal conditions associated with decreased epithelial cell barrier function or integrity. Further, the disclosed therapeutic proteins are useful for treating human inflammatory bowel disease, including inter alia, Crohn's disease and ulcerative colitis.

Abstract: A system and method for determining enterprise metrics of an enterprise application is described. The system identifies a plurality of users of an enterprise. The system accesses enterprise usage data of an enterprise application from user accounts of an enterprise. The system accesses a profile of the enterprise and computes a first plurality of metrics based on the enterprise usage data and the profile of the enterprise. The system computes a first plurality of indexes based on the first plurality of metrics. The system then identities a plurality of benchmark indexes based on the profile of the enterprise. A graphical user interface indicating the first plurality of indexes relative to the plurality of benchmark indexes is generated.

Abstract: A cooling, carbonation and dispensing system for use with a liquid in a keg includes a cooling ring contacting the keg. The cooling ring provides an opening through which dry ice is placed. The cooling ring and dry ice provide contact cooling of the keg, as well as carbon dioxide gas by sublimation of the dry ice to carbonate the liquid in the keg and pressure on the liquid so that it may be dispensed from the keg. A chilling unit having a hose bundle is adjacent the keg and the cooling ring. A liquid dispensing hose from the keg coupler on the keg connects to the hose bundle, so that liquid from the keg passes through the hose bundle. A lid having a tower is attached to the top of the chilling unit and latched to it to form a water-tight seal. Another hose connects to the hose bundle in the chilling unit and conducts the liquid to a dispensing hose attached to a dispenser in the tower. Wet ice is placed in the chilling unit and the tower to provide further chilling (flash chilling) of the liquid.

Abstract: A cooling, carbonation and dispensing system for use with a liquid in a keg includes a cooling ring mounted on top of the keg. The cooling ring includes a toroidal-shaped shell into which dry ice is placed. The cooling ring and dry ice provide contact cooling of the keg, as well as carbon dioxide gas by sublimation of the dry ice to carbonate the liquid in the keg and pressure on the liquid so that it may be dispensed from the keg. A chilling unit having a hose bundle is mounted on top of the cooling ring. A liquid dispensing hose from the keg coupler on the keg connects to the hose bundle, so that liquid from the keg passes through the hose bundle. A lid having a tower is attached to the top of the chilling unit and latched to it to form a water-tight seal. Another hose connects to the hose bundle in the chilling unit and conducts the liquid to a dispensing hose attached to a dispenser in the tower.

Abstract: A cooling, carbonation and dispensing system for use with a liquid in a keg includes a cooling ring mounted on top of the keg. The cooling ring includes a toroidal-shaped shell into which dry ice is placed. The cooling ring and dry ice provide contact cooling of the keg, as well as carbon dioxide gas by sublimation of the dry ice to carbonate the liquid in the keg and pressure on the liquid so that it may be dispensed from the keg. A chilling unit having a hose bundle is mounted on top of the cooling ring. A liquid dispensing hose from the keg coupler on the keg connects to the hose bundle, so that liquid from the keg passes through the hose bundle. A lid having a tower is attached to the top of the chilling unit and latched to it to form a water-tight seal. Another hose connects to the hose bundle in the chilling unit and conducts the liquid to a dispensing hose attached to a dispenser in the tower.