Patents by Inventor Andrew John Duffield

Andrew John Duffield has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Uses of combinations (+)-?-dihydrotetrabenazine and (?)-?-dihydrotetrabenazine in methods of treating movement disorder
    Patent number: 11844786
    Abstract: The invention relates to pharmaceutical compositions containing both (+)-?-dihydrotetrabenazine and (?)-?-dihydrotetrabenazine and their therapeutic uses, for example in the treatment of movement disorders, such as Tourette's syndrome.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: December 19, 2023
    Assignee: ADEPTIO PHARMACEUTICALS LIMITED
    Inventors: Andrew John Duffield, Anant Pandya
  • Pharmaceutical compositions
    Patent number: 11844794
    Abstract: The invention provides (+)-?-dihydrotetrabenazine succinate salt. Also provided are (+)-?-dihydrotetrabenazine succinate salt for use in medicine, pharmaceutical compositions comprising (+)-?-dihydrotetrabenazine succinate salt and a pharmaceutically acceptable excipient and the uses of (+)-?-dihydrotetrabenazine succinate salt as a VMAT2 receptor antagonist and in the treatment of a movement disorder such as Tourette's syndrome. The invention further provides a method for preparing the (+)-?-dihydrotetrabenazine succinate salt.
    Type: Grant
    Filed: July 26, 2021
    Date of Patent: December 19, 2023
    Assignee: ADEPTIO PHARMACEUTICALS LIMITED
    Inventors: Andrew John Duffield, Anant Pandya
  • USES OF (+)-A-DIHYDROTETRABENAZINE IN METHODS OF TREATING MOVEMENT DISORDER
    Publication number: 20220211678
    Abstract: This invention relates to the use of low doses of (+)-?-dihydrotetrabenazine for the treatment of movement disorders, such as Tourette's syndrome.
    Type: Application
    Filed: January 14, 2022
    Publication date: July 7, 2022
    Applicant: ADEPTIO PHARMACEUTICALS LIMITED
    Inventors: Andrew John DUFFIELD, Anant PANDYA
  • PHARMACEUTICAL COMPOSITIONS
    Publication number: 20220016107
    Abstract: The invention provides (+)-?-dihydrotetrabenazine succinate salt. Also provided are (+)-?-dihydrotetrabenazine succinate salt for use in medicine, pharmaceutical compositions comprising (+)-?-dihydrotetrabenazine succinate salt and a pharmaceutically acceptable excipient and the uses of (+)-?-dihydrotetrabenazine succinate salt as a VMAT2 receptor antagonist and in the treatment of a movement disorder such as Tourette's syndrome. The invention further provides a method for preparing the (+)-?-dihydrotetrabenazine succinate salt.
    Type: Application
    Filed: July 26, 2021
    Publication date: January 20, 2022
    Applicant: ADEPTIO PHARMACEUTICALS LIMITED
    Inventors: Andrew John DUFFIELD, Anant PANDYA
  • Pharmaceutical compositions
    Patent number: 11103498
    Abstract: The invention provides (+)-?-dihydrotetrabenazine succinate salt. Also provided are (+)-?-dihydrotetrabenazine succinate salt for use in medicine, pharmaceutical compositions comprising (+)-?-dihydrotetrabenazine succinate salt and a pharmaceutically acceptable excipient and the uses of (+)-?-dihydrotetrabenazine succinate salt as a VMAT2 receptor antagonist and in the treatment of a movement disorder such as Tourette's syndrome. The invention further provides a method for preparing the (+)-?-dihydrotetrabenazine succinate salt.
    Type: Grant
    Filed: April 17, 2020
    Date of Patent: August 31, 2021
    Assignee: ADEPTIO PHARMACEUTICALS LIMITED
    Inventors: Andrew John Duffield, Anant Pandya
  • PHARMACEUTICAL COMPOUNDS FOR USE IN TREATING HUNTINGTON'S DISEASE
    Publication number: 20210236479
    Abstract: The invention provides (+)-?-dihydrotetrabenazine or a pharmaceutically acceptable salt thereof for use in reducing the life-shortening effect of Huntington's Disease in mammals. Also provided by the invention are (+)-?-dihydrotetrabenazine or a pharmaceutically acceptable salt thereof for use in preventing or delaying the onset of late stage Huntington's Disease; or for use in preventing or delaying the onset of life-threatening symptoms or events exhibited during late stage Huntington's disease.
    Type: Application
    Filed: May 22, 2019
    Publication date: August 5, 2021
    Applicant: ADEPTIO PHARMACEUTICALS LIMITED
    Inventors: Andrew John DUFFIELD, Anant PANDYA
  • Dihydrotetrabenazine for the treatment of anxiety and psychoses
    Patent number: 11065232
    Abstract: This invention relates to pharmaceutical compositions containing (?)-?-dihydrotetrabenazine, processes for making them and their therapeutic uses.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: July 20, 2021
    Assignee: ADEPTIO PHARMACEUTICALS LIMITED
    Inventors: Andrew John Duffield, Anant Pandya
  • PHARMACEUTICAL COMPOSITIONS
    Publication number: 20200246324
    Abstract: The invention provides (+)-?-dihydrotetrabenazine succinate salt. Also provided are (+)-?-dihydrotetrabenazine succinate salt for use in medicine, pharmaceutical compositions comprising (+)-?-dihydrotetrabenazine succinate salt and a pharmaceutically acceptable excipient and the uses of (+)-?-dihydrotetrabenazine succinate salt as a VMAT2 receptor antagonist and in the treatment of a movement disorder such as Tourette's syndrome. The invention further provides a method for preparing the (+)-?-dihydrotetrabenazine succinate salt.
    Type: Application
    Filed: April 17, 2020
    Publication date: August 6, 2020
    Applicant: ADEPTIO PHARMACEUTICALS LIMITED
    Inventors: Andrew John DUFFIELD, Anant PANDYA
  • Combinations of isomers of dihydrotetrabenazine
    Patent number: 10668052
    Abstract: This invention relates to the use of combinations of stereoisomers of dihydrotetrabenazine for the treatment of movement disorders, such as Tourette's syndrome.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: June 2, 2020
    Assignee: ADEPTIO PHARMACEUTICALS LIMITED
    Inventors: Andrew John Duffield, Anant Pandya
  • Pharmaceutical compositions
    Patent number: 10660885
    Abstract: The invention provides (+)-?-dihydrotetrabenazine succinate salt. Also provided are (+)-?-dihydrotetrabenazine succinate salt for use in medicine, pharmaceutical compositions comprising (+)-?-dihydrotetrabenazine succinate salt and a pharmaceutically acceptable excipient and the uses of (+)-?-dihydrotetrabenazine succinate salt as a VMAT2 receptor antagonist and in the treatment of a movement disorder such as Tourette's syndrome. The invention further provides a method for preparing the (+)-?-dihydrotetrabenazine succinate salt.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: May 26, 2020
    Assignee: ADEPTIO PHARMACEUTICALS LIMITED
    Inventors: Andrew John Duffield, Anant Pandya
  • DIHYDROTETRABENAZINE FOR THE TREATMENT OF ANXIETY AND PSYCHOSES
    Publication number: 20200038384
    Abstract: This invention relates to pharmaceutical compositions containing (?)-?-dihydrotetrabenazine, processes for making them and their therapeutic uses.
    Type: Application
    Filed: March 29, 2018
    Publication date: February 6, 2020
    Applicant: ADEPTIO PHARMACEUTICALS LIMITED
    Inventors: Andrew John DUFFIELD, Anant PANDYA
  • PHARMACEUTICAL COMPOSITIONS
    Publication number: 20190111035
    Abstract: This invention relates to the use of low doses of (+)-?-dihydrotetrabenazine for the treatment of movement disorders, such as Tourette's syndrome.
    Type: Application
    Filed: October 4, 2018
    Publication date: April 18, 2019
    Applicant: ADEPTIO PHARMACEUTICALS LIMITED
    Inventors: Andrew John DUFFIELD, Anant PANDYA
  • PHARMACEUTICAL COMPOSITIONS
    Publication number: 20180280360
    Abstract: This invention relates to pharmaceutical compositions containing (+)-?-dihydrotetrabenazine and their therapeutic uses, in particular in their use in the treatment of movement disorders, such as Tourette's syndrome.
    Type: Application
    Filed: March 29, 2018
    Publication date: October 4, 2018
    Applicant: ADEPTIO PHARMACEUTICALS LIMITED
    Inventors: Andrew John DUFFIELD, Anant PANDYA
  • PHARMACEUTICAL COMPOSITIONS
    Publication number: 20180280361
    Abstract: This invention relates to the use of combinations of stereoisomers of dihydrotetrabenazine for the treatment of movement disorders, such as Tourette's syndrome.
    Type: Application
    Filed: March 29, 2018
    Publication date: October 4, 2018
    Applicant: ADEPTIO PHARMACEUTICALS LIMITED
    Inventors: Andrew John DUFFIELD, Anant PANDYA
  • PHARMACEUTICAL COMPOSITIONS
    Publication number: 20180280359
    Abstract: The invention relates to pharmaceutical compositions containing both (+)-?-dihydrotetrabenazine and (?)-?-dihydrotetrabenazine and their therapeutic uses, for example in the treatment of movement disorders, such as Tourette's syndrome.
    Type: Application
    Filed: March 29, 2018
    Publication date: October 4, 2018
    Applicant: ADEPTIO PHARMACEUTICALS LIMITED
    Inventors: Andrew John DUFFIELD, Anant PANDYA
  • PHARMACEUTICAL COMPOSITIONS
    Publication number: 20180280374
    Abstract: This invention relates to the use of low doses of (+)-?-dihydrotetrabenazine for the treatment of movement disorders, such as Tourette's syndrome.
    Type: Application
    Filed: March 29, 2018
    Publication date: October 4, 2018
    Applicant: ADEPTIO PHARMACEUTICALS LIMITED
    Inventors: Andrew John DUFFIELD, Anant PANDYA
  • PHARMACEUTICAL COMPOSITIONS
    Publication number: 20180280375
    Abstract: The invention provides (+)-?-dihydrotetrabenazine succinate salt. Also provided are (+)-?-dihydrotetrabenazine succinate salt for use in medicine, pharmaceutical compositions comprising (+)-?-dihydrotetrabenazine succinate salt and a pharmaceutically acceptable excipient and the uses of (+)-?-dihydrotetrabenazine succinate salt as a VMAT2 receptor antagonist and in the treatment of a movement disorder such as Tourette's syndrome. The invention further provides a method for preparing the (+)-?-dihydrotetrabenazine succinate salt.
    Type: Application
    Filed: March 29, 2018
    Publication date: October 4, 2018
    Applicant: ADEPTIO PHARMACEUTICALS LIMITED
    Inventors: Andrew John DUFFIELD, Anant PANDYA
  • PHARMACEUTICAL COMPOSITIONS
    Publication number: 20140242063
    Abstract: The present invention provides for a pharmaceutical composition that includes tetrabenazine and a release-retarding agent; and a method of treating a hyperkinetic movement disorder (e.g., Huntington's disease, chorea associated with Huntington's disease, hemiballismus, senile chorea, tic disorders, tardive dyskinesia, myoclonus, dystonia and/or Tourette's syndrome). The method includes administering an effective amount of the pharmaceutical composition, for a period of time effective to treat the hyperkinetic movement disorder.
    Type: Application
    Filed: October 10, 2013
    Publication date: August 28, 2014
    Applicant: VALEANT LABORATORIES INTERNATIONAL BERMUDA
    Inventors: Andrew John DUFFIELD, Graham JACKSON, Steven E. FRISBEE
  • Pharmaceutical Compositions
    Publication number: 20140030249
    Abstract: The present invention provides for a pharmaceutical composition that includes tetrabenazine and a release-retarding agent; and a method of treating a hyperkinetic movement disorder (e.g., Huntington's disease, chorea associated with Huntington's disease, hemiballismus, senile chorea, tic disorders, tardive dyskinesia, myoclonus, dystonia and/or Tourette's syndrome). The method includes administering an effective amount of the pharmaceutical composition, for a period of time effective to treat the hyperkinetic movement disorder.
    Type: Application
    Filed: September 27, 2013
    Publication date: January 30, 2014
    Applicant: Valeant International Bermuda
    Inventors: Andrew John DUFFIELD, Graham Jackson, Steven E. Frisbee, Okponanabofa Eradiri, John CK Lai
  • PHARMACEUTICAL COMPOSITIONS WITH TETRABENAZINE
    Publication number: 20120208773
    Abstract: The present invention provides for a pharmaceutical composition that includes tetrabenazine and a release-retarding agent; and a method of treating a hyperkinetic movement disorder (e.g., Huntington's disease, chorea associated with Huntington's disease, hemiballismus, senile chorea, tic disorders, tardive dyskinesia, myoclonus, dystonia and/or Tourette's syndrome). The method includes administering an effective amount of the pharmaceutical composition, for a period of time effective to treat the hyperkinetic movement disorder.
    Type: Application
    Filed: August 12, 2010
    Publication date: August 16, 2012
    Applicant: Valeant International (Barbados) SRL
    Inventors: Andrew John Duffield, Graham Jackson, Steven E. Frisbee, Okponanabofa Eradiri, John CK Lai