Patents by Inventor Andrew John Tofe

Andrew John Tofe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Radionuclide carriers
    Patent number: 4002730
    Abstract: Physiologically acceptable particulate radionuclide carriers comprising a reducing agent bound to an anionic starch derivative, useful in the preparation of organ-specific diagnostic radiopharmaceuticals.
    Type: Grant
    Filed: January 13, 1975
    Date of Patent: January 11, 1977
    Assignee: The Procter & Gamble Company
    Inventors: Frederick Anthony Hartman, Herbert Charles Kretschmar, Andrew John Tofe
  • Dry mixture containing diphosphonates and a stannous salt useful in the preparation of Tc.sup.99M containing bone scanning agents
    Patent number: 3983227
    Abstract: A composition and method for the preparation of a technetium-99m based scintigraphic scanning agent are disclosed. The agent is prepared by the addition of a pertechnetate-99m solution to an anhydrous salt composition comprising a phosphonic acid or a pharmaceutically acceptable salt thereof and a non-toxic, water-soluble, anhydrous, stannous, ferrous or chromous salt of hydrochloric or sulfuric acid.
    Type: Grant
    Filed: April 19, 1974
    Date of Patent: September 28, 1976
    Assignee: The Procter & Gamble Company
    Inventors: Andrew John Tofe, Marion David Francis
  • Compositions for the treatment of calcific tumors
    Patent number: 3965254
    Abstract: Composition in unit dosage form comprising mono-, di- and polyphosphonate compounds having therapeutic levels of radioactive phosphorus (as .sup.32 P and .sup.33 P) incorporated therein are disclosed. Due to the extremely high affinity of the polyphosphonate compounds for active bone tumors and their exceptionally low retention in soft tissue they are ideal for therapy of both primary and metastatic bone tumors and soft tissue tumors which calcify.
    Type: Grant
    Filed: November 15, 1974
    Date of Patent: June 22, 1976
    Assignee: The Procter & Gamble Company
    Inventors: Andrew John Tofe, Marion David Francis