Abstract: A system and method is disclosed for evaluating a plurality of cryptocurrencies, the method comprising monitoring and storing volatility data for a plurality of cryptocurrency exchanges; analyzing the stored volatility data to generate one or more risk forecasts indicating risks associated with purchasing cryptocurrency through each of the cryptocurrency exchanges; determining a number of transaction factors for purchasing cryptocurrencies and selecting a cryptocurrency based on the transaction factors.

Abstract: A multipoint lock including a pivoting lock bolt including a fixed pivot point and a sliding pivot point, a translating lock bolt, a linkage coupled to and configured to pivot the pivoting lock bolt and to translate the translating lock bolt, an actuation mechanism configured to actuate the linkage and to effect pivoting of the pivoting lock bolt and translation of the translating lock bolt, and an input mechanism configured to receive user input and transmit the user input to the actuation mechanism, the user unput including shifting the input mechanism between an unlocked position and a locked position.

Abstract: One or more techniques and/or systems are disclosed for an improved barrier seal for use on a rotating shaft of a pump to mitigate leakage of fluids along the shaft. The body of the barrier seal may comprise a one-piece combined bushing and seal that can be selectably fastened to the pump bracket. Internal and external channels in the body can operably hold gaskets, internally dynamic seals, and externally static seals, inside the stuffing box of the pump bracket. A lubricant port can be disposed on a flange of the seal portion to provide lubricant to the interior of the barrier seal, which can also be fluidly coupled with the outside of the seal. A pressurized lubricating fluid can also help mitigate leakage of pumped fluid by pressurizing between static gaskets on the outside, and provide lubrication for the rotating shaft on the inside of the seal.

Abstract: A plumbing device including a body with at least one inlet and at least one outlet and a number of fluid control mechanisms, wherein each fluid control mechanism performs a different fluid control function compared to the other fluid control mechanisms and wherein the body houses the fluid control mechanisms.

Abstract: One or more techniques and/or systems are disclosed for a universal-type bracket that incorporates a substantially uniform diameter through-bore. This allows the bracket to accept current sealing arrangements used in these types of pumps, while providing the same or better sealing options as current individual designs. The single through-bore can have multiple undercut features for holding a pump shaft bushing, with an increased wall thickness to allow for an appropriate interference fit with the walls of the through-bore, for example, similar to previous designs. Retaining ring grooves can be added to the through-bore, and retaining rings may be used to provide a positive shoulder for the seal or packing rings to seat against inside the bore. This may allow for various sealing options, such as stuffing seals, one-piece barrier seals, cartridge seals, BTR seals, component seals, and more.

Abstract: A handheld controller configured to be held by a user's hand. The handheld controller comprising a main body, and a handle extending from the main body, wherein the handle has a palm side and a finger side. A control button is positioned on the main body or handle, and a detection sensor is on the handle. The detection sensor is positioned to detect the presence of the finger or palm of a user's hand engaging the handle. The detection sensor can be a capacitive touch sensor, a proximity sensor or other detection sensor operative to detect the touch or spatial presence of the user's hand or fingers.

Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.

Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.

Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.

Abstract: A series of fused pentacyclic imidazole derivatives, being potent modulators of human TNFa activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders. In particular, the present invention is concerned with 6, 7-dihydro-7, 14-methanobenzimidazo[1, 2-b][2,5]benzodiazocin-5(14H)-one derivatives and analogs thereof.

Abstract: Apparatuses, systems, and methods for brewing a desired portion of a beverage, such as a single-cup portion of coffee, are provided. The system can include one or more hopper assemblies configured to provide a controlled dose of beverage material to a brew chamber. The system can also include a water input system configured to wet the ground beverage material as the grinds enter the brew chamber and substantially prevent steam from reaching grinder components of the system. Further, the system can include an automatic cleaning mechanism such that a user does not need to manually clean components of a brewing machine between brew cycles.

Abstract: An apparatus includes a housing that defines a fluid reservoir and includes a port that is in fluid communication with the fluid reservoir. An inlet adapter is removably coupleable to the housing. A user can engage an actuator to move a plunger from a first position in which the fluid reservoir has a first volume, to a second position in which the fluid reservoir has a second volume greater than the first volume, which draws bodily fluid into the fluid reservoir via the inlet adapter. The actuator modulates a plunger rate of motion below a threshold as the plunger is moved. When a predetermined volume of bodily fluid is transferred into the fluid reservoir, a volume indicator transitions from a first state to a second state and the inlet adapter can then be removed to transfer the predetermined volume into a sample bottle external to the housing via the port.

Abstract: Embodiments herein relate to hearing assistance systems and methods for use with assistive listening device systems. In a first aspect, a hearing assistance system is included having an ear-worn device can include a control circuit, a sensor package in signal communication with the control circuit, a power supply circuit in electrical communication with the control circuit, and a spatial locator circuit in communication with the ear-worn device. The spatial locator circuit can detect a current spatial location. The system can compare the current spatial location against entries in a database of spatial locations that offer assistive listening device services. The system can send a notification to the ear-worn device and/or ear-worn device wearer if the current spatial location is found in the database of spatial locations that offer assistive listening device services. Other embodiments are also included herein.

Abstract: A method of recording images within a furnace using a thermal imaging camera comprising a bore scope connected to a digital camera unit is described, comprising the steps of: (a) inserting the borescope into the interior of the furnace, (b) collecting one of more images of the interior of the furnace using the thermal imaging camera with the borescope at a first position, and (c) moving the borescope from the first position to a second position and collecting one or more images of the interior of the furnace as the borescope is moved from the first position to the second position, wherein the borescope movement is guided by means of a guide device comprising a movable borescope mounting, mounted externally on the furnace.

Abstract: A method of presenting construction-related information to a user is provided. The method comprises, at a computing device, receiving a user selection for a construction region, and retrieving image data for one or more construction components that form part of the selected construction region. The method further comprises retrieving construction information defining a construction requirement associated with one or more of the construction components, and rendering a first enhanced construction image that combines the retrieved image data for the construction components with a schematic representation of the construction information. The method may comprise receiving sensor data indicative of a location of the computing device, ascertaining a current location or geographical area of the computing device based on the received sensor data, and retrieving geospatial information associated with both the current location or geographical area and one or more of the construction components.

Abstract: Methods and systems for implementing a Jupiter aerospace mission can enable delivery of a science payload to a Jupiter orbit on a direct Earth-to-Jupiter trajectory. Solar power and use of avionics also allow a fast assembly, integration, and test process compared to past outer Solar System missions. The spacecraft can include an aerodynamic forebody, a shell, and a thermal protection system. The spacecraft can manage the radiation environment, generate solar power, and return data to Earth with a robust radio-frequency (RF) amplification and antenna gain.

Abstract: A nanoparticle agent includes a gold nanoparticle, at least one thiol modified Gd(III) macrocycle complex, and at least one prostate specific membrane antigen (PSMA) ligand, wherein the PSMA ligand and the thiol modified Gd(III) complex are each individually coupled to the gold nanoparticle via one or more thiol (SH) groups.

Abstract: Intraocular physiological sensor implants include a physiological sensor, and a housing comprising a faceplate. The physiological sensor is integrated with the faceplate. The physiological sensor typically comprises an intraocular pressure sensor, such as a capacitive pressure sensor that may further include a flexible diaphragm electrode spaced apart from a counter electrode. The intraocular pressure sensor detects intraocular pressure, to identify patient conditions such as glaucoma.

Abstract: An apparatus includes a housing that defines a fluid reservoir and includes a port that is in fluid communication with the fluid reservoir. An inlet adapter is removably coupleable to the housing. A user can engage an actuator to move a plunger from a first position in which the fluid reservoir has a first volume, to a second position in which the fluid reservoir has a second volume greater than the first volume, which draws bodily fluid into the fluid reservoir via the inlet adapter. The actuator modulates a plunger rate of motion below a threshold as the plunger is moved. When a predetermined volume of bodily fluid is transferred into the fluid reservoir, a volume indicator transitions from a first state to a second state and the inlet adapter can then be removed to transfer the predetermined volume into a sample bottle external to the housing via the port.

Abstract: A method and apparatus for job submission are described. In one embodiment, the jobs are submitted by a job submission service or gateway that schedules large-scale data processing jobs on remote infrastructure. In one embodiment, the method comprises: receiving a request at a proxy service from a client, via a network communication, to submit a job to a cluster; and managing the job externally to the client, including sending a request to an orchestration system to launch an orchestration system job in a container to start the job running on the cluster via a client process run on a job client in the container and provide state information back to the proxy service regarding the orchestration system job.