Patents by Inventor Andrew K. McPherson

Andrew K. McPherson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYNTHESIS OF OLIGOMERIC COMPOUNDS COMPRISING PHOSPHOROTHIOATE DIESTER AND PHOSPHODIESTER LINKAGES
    Publication number: 20220251128
    Abstract: The present disclosure provides methods for synthesizing oligomeric compounds having at least one phosphorothioate diester linkage and at least one phosphate diester internucleoside linkage. In certain embodiments, the present disclosure provides oxidation reagents that produce low amounts of unwanted phosphate diester impurities in oligomeric compounds having at least one phosphorothioate diester linkage and at least one phosphate diester internucleoside linkage.
    Type: Application
    Filed: May 15, 2020
    Publication date: August 11, 2022
    Applicant: Ionis Pharmaceuticals, Inc.
    Inventors: Andrew K. McPherson, Andrew A. Rodriguez, Daniel C. Capaldi