Patents by Inventor Andrew Kale

Andrew Kale has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for inhibiting proteases
    Patent number: 9409944
    Abstract: In particular, in alternative embodiments, the invention provides pharmaceutical compounds and formulations comprising a family of epoxyketone compounds, which include racemic mixtures or racemates, isomers, stereoisomers, diastereoisomers, derivatives and analogs, and methods for making and using them. In alternative embodiments, pharmaceutical compositions and formulations of the invention are administered to an individual in need thereof in an amount sufficient to treat, prevent, reverse and/or ameliorate an infection, disease or condition that can be ameliorated, treated, prevented or reversed by partially or completely inhibiting a chymotrypsin-like protease or a proteasome activity, including e.g.
    Type: Grant
    Filed: July 12, 2012
    Date of Patent: August 9, 2016
    Assignee: The Regents of the University of California
    Inventors: William H. Gerwick, Alban R. Pereira-Badilla, Tara Byrum, Frederick A. Valeriote, Michael Kenneth Gilson, Andrew T. Fenley, Bradley S. Moore, Andrew Kale, Hosana Debonsi
  • COMPOSITIONS AND METHODS FOR INHIBITING PROTEASES
    Publication number: 20140248333
    Abstract: In particular, in alternative embodiments, the invention provides pharmaceutical compounds and formulations comprising a family of epoxyketone compounds, which include racemic mixtures or racemates, isomers, stereoisomers, diastereoisomers, derivatives and analogs, and methods for making and using them. In alternative embodiments, pharmaceutical compositions and formulations of the invention are administered to an individual in need thereof in an amount sufficient to treat, prevent, reverse and/or ameliorate an infection, disease or condition that can be ameliorated, treated, prevented or reversed by partially or completely inhibiting a chymotrypsin-like protease or a proteasome activity, including e.g.
    Type: Application
    Filed: July 12, 2012
    Publication date: September 4, 2014
    Applicants: JOSEPHINE FORD CANCER CENTER, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: William H. Gerwick, Alban R. Pereira-Badilla, Tara Byrum, Frederick A. Valeriote, Michael Kenneth Gilson, Andrew Fenley, Bradley S. Moore, Andrew Kale, Hosana M. Debonsi