Abstract: Provided herein are materials and methods for detecting colorectal neoplasms and colon cancer based on the expression levels of stool-derived eukaryotic RNA biomarkers in eukaryotic nucleic acid present in a stool sample from a subject, for example, a patient. The methods can be used for the detection of high-risk adenomas and colorectal neoplasm molecular subtypes.

Abstract: Systems and methods are provided for migration of users to one or more services offered by a service host. An exemplary method includes detecting, by a computing device associated with the service host, a first dispute message associated with a user and transmitted from a dispute service of the service host to a clearing service of the service host, and appending the user to a black list in response to the first dispute message. The method also includes detecting, by the computing device, a second dispute message associated with the user and transmitted to the clearing service, determining whether the user is included in the black list, and rejecting the second dispute message when the user is included in the black list, thereby inhibiting the user from transmitting the second dispute message to the clearing service outside of the dispute service.

Abstract: Systems and methods are provided for migration of users to one or more services offered by a service host. An exemplary method includes detecting, by a computing device associated with the service host, a first dispute message associated with a user and transmitted from a dispute service of the service host to a clearing service of the service host, and appending the user to a black list in response to the first dispute message. The method also includes detecting, by the computing device, a second dispute message associated with the user and transmitted to the clearing service, determining whether the user is included in the black list, and rejecting the second dispute message when the user is included in the black list, thereby inhibiting the user from transmitting the second dispute message to the clearing service outside of the dispute service.

Abstract: A recommender system for use on a mobile platform or other computing device provides a user with a recommended list of products with default product quantities that are based on prior purchase behavior of the user or customer. This feature relies on analyzing a customer's past purchases and associating a score with each product. The scoring system indicates the statistical likelihood that the customer would want or need to purchase that item on their next order. The customer analysis takes into account, e.g., the number of times a customer has ordered a product, how frequently the product is ordered by the customer, how many days since the respective customers last order and the customers average order size in providing the recommended list of products.

Abstract: The present invention has demonstrated for the first time that orally administered type I collagen (CI) induced tolerance to CI in patients suffering from systemic sclerosis (SSc) and ameliorated clinical manifestations of the disease. Accordingly, the present invention provides methods of treating a fibrosing disease by oral administration of a tissue protein, for example, collagen, derived from the tissue undergoing fibrosis.

Abstract: Peptides corresponding to amino acid sequences in the C-terminal region of TGF-.beta. are provided. The peptides all contain at least a seven amino acid sequence substantially corresponding to the amino acid sequence of TGF-.beta.1 amino acids 368-374: VYYVGRK, as well as homologs and analogs thereof. The peptides have chemotactic activity towards fibroblasts, monocytes and neutrophils and induce fibroblast proliferation and collagen synthesis. The peptides may be used in compositions and methods for promoting wound healing.

Abstract: Peptides corresponding to an no acid sequences in the C-terminal region of TGF-.beta. are provided. The peptides all contain at least a seven amino acid sequence substantially corresponding to the amino acid sequence of TGF-.beta.1 amino acids 368-374: VYYVGRK, as well as homologs and analogs thereof. The peptides have chemotactic activity towards fibroblasts, monocytes and neutrophils and induce fibroblast proliferation and collagen synthesis. The peptides may be used in compositions and methods for promoting wound healing.