Patents by Inventor Andrew Kozbial

Andrew Kozbial has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11952563
    Abstract: A cell culture cartridge is provided comprising a plurality of zones geometrically configured to provide for symmetrical fluid flow with each of the plurality of zones to avoid dead areas in flow within each of the plurality of zones. In certain embodiments, at least eight inlets are provided, with an inlet positioned at each corner of the cell culture cartridge. In certain embodiments, a shared outlet is positioned on a top surface of the cell culture cartridge.
    Type: Grant
    Filed: May 4, 2022
    Date of Patent: April 9, 2024
    Assignee: FLASKWORKS, LLC
    Inventor: Andrew Kozbial
  • Publication number: 20230039516
    Abstract: Cell culture systems and methods provide improved immunotherapeutic product manufacturing with greater scalability, flexibility, and automation. Cell culture systems are configured with interchangeable cartridges, allowing versatility and scalability. Systems are configured to have multiple connected cell culture chambers, which allows parallel processing of different types of cells. Gas-impermeable cell culture chambers and methods for generating cells in closed systems prevent contamination and user error. Methods for recycling cell culture medium provide additional efficiencies.
    Type: Application
    Filed: August 11, 2022
    Publication date: February 9, 2023
    Inventors: Shashi K. Murthy, Andrew Kozbial
  • Publication number: 20230030481
    Abstract: Cell culture systems and methods provide improved immunotherapeutic product manufacturing with greater scalability, flexibility, and automation. Cell culture systems are configured with interchangeable cartridges, allowing versatility and scalability. Systems are configured to have multiple connected cell culture chambers, which allows parallel processing of different types of cells. Gas-impermeable cell culture chambers and methods for generating cells in closed systems prevent contamination and user error. Methods for recycling cell culture medium provide additional efficiencies.
    Type: Application
    Filed: August 11, 2022
    Publication date: February 2, 2023
    Inventors: Shashi K. Murthy, Andrew Kozbial
  • Publication number: 20220340850
    Abstract: A cell culture cartridge is provided comprising a plurality of zones geometrically configured to provide for symmetrical fluid flow with each of the plurality of zones to avoid dead areas in flow within each of the plurality of zones. In certain embodiments, at least eight inlets are provided, with an inlet positioned at each corner of the cell culture cartridge. In certain embodiments, a shared outlet is positioned on a top surface of the cell culture cartridge.
    Type: Application
    Filed: May 4, 2022
    Publication date: October 27, 2022
    Inventor: Andrew Kozbial
  • Publication number: 20220306977
    Abstract: Cell culture systems and methods provide improved immunotherapeutic product manufacturing with greater scalability, flexibility, and automation. Cell culture systems are configured with interchangeable cartridges, allowing versatility and scalability. Systems are configured to have multiple connected cell culture chambers, which allows parallel processing of different types of cells. Gas-impermeable cell culture chambers and methods for generating cells in closed systems prevent contamination and user error. Methods for recycling cell culture medium provide additional efficiencies.
    Type: Application
    Filed: June 16, 2022
    Publication date: September 29, 2022
    Inventors: Shashi K. Murthy, Andrew Kozbial
  • Patent number: 11447732
    Abstract: Cell culture systems and methods provide improved immunotherapeutic product manufacturing with greater scalability, flexibility, and automation. Cell culture systems are configured with interchangeable cartridges, allowing versatility and scalability. Systems are configured to have multiple connected cell culture chambers, which allows parallel processing of different types of cells. Gas-impermeable cell culture chambers and methods for generating cells in closed systems prevent contamination and user error. Methods for recycling cell culture medium provide additional efficiencies.
    Type: Grant
    Filed: October 20, 2020
    Date of Patent: September 20, 2022
    Assignee: FLASKWORKS, LLC
    Inventors: Shashi K. Murthy, Andrew Kozbial
  • Patent number: 11434459
    Abstract: Cell culture systems and methods provide improved immunotherapeutic product manufacturing with greater scalability, flexibility, and automation. Cell culture systems are configured with interchangeable cartridges, allowing versatility and scalability. Systems are configured to have multiple connected cell culture chambers, which allows parallel processing of different types of cells. Gas-impermeable cell culture chambers and methods for generating cells in closed systems prevent contamination and user error. Methods for recycling cell culture medium provide additional efficiencies.
    Type: Grant
    Filed: October 20, 2020
    Date of Patent: September 6, 2022
    Assignee: FLASKWORKS, LLC
    Inventors: Shashi K. Murthy, Andrew Kozbial
  • Publication number: 20220235305
    Abstract: Cell culture systems and methods provide improved immunotherapeutic product manufacturing with greater scalability, flexibility, and automation. Cell culture systems are configured with interchangeable cartridges, allowing versatility and scalability. Systems are configured to have multiple connected cell culture chambers, which allows parallel processing of different types of cells. Gas-impermeable cell culture chambers and methods for generating cells in closed systems prevent contamination and user error. Methods for recycling cell culture medium provide additional efficiencies.
    Type: Application
    Filed: February 16, 2022
    Publication date: July 28, 2022
    Inventors: Shashi K. Murthy, Andrew Kozbial
  • Patent number: 11339363
    Abstract: A cell culture cartridge is provided comprising a plurality of zones geometrically configured to provide for symmetrical fluid flow with each of the plurality of zones to avoid dead areas in flow within each of the plurality of zones. In certain embodiments, at least eight inlets are provided, with an inlet positioned at each corner of the cell culture cartridge. In certain embodiments, a shared outlet is positioned on a top surface of the cell culture cartridge.
    Type: Grant
    Filed: April 6, 2020
    Date of Patent: May 24, 2022
    Assignee: FLASKWORKS, LLC
    Inventor: Andrew Kozbial
  • Patent number: 11268058
    Abstract: Cell culture systems and methods provide improved immunotherapeutic product manufacturing with greater scalability, flexibility, and automation. Cell culture systems are configured with interchangeable cartridges, allowing versatility and scalability. Systems are configured to have multiple connected cell culture chambers, which allows parallel processing of different types of cells. Gas-impermeable cell culture chambers and methods for generating cells in closed systems prevent contamination and user error. Methods for recycling cell culture medium provide additional efficiencies.
    Type: Grant
    Filed: October 20, 2020
    Date of Patent: March 8, 2022
    Assignee: FLASKWORKS, LLC
    Inventors: Shashi K. Murthy, Andrew Kozbial
  • Publication number: 20210115374
    Abstract: Cell culture systems and methods provide improved immunotherapeutic product manufacturing with greater scalability, flexibility, and automation. Cell culture systems are configured with interchangeable cartridges, allowing versatility and scalability. Systems are configured to have multiple connected cell culture chambers, which allows parallel processing of different types of cells. Gas-impermeable cell culture chambers and methods for generating cells in closed systems prevent contamination and user error. Methods for recycling cell culture medium provide additional efficiencies.
    Type: Application
    Filed: October 20, 2020
    Publication date: April 22, 2021
    Inventors: Shashi K. Murthy, Andrew Kozbial
  • Publication number: 20210115402
    Abstract: Cell culture systems and methods provide improved immunotherapeutic product manufacturing with greater scalability, flexibility, and automation. Cell culture systems are configured with interchangeable cartridges, allowing versatility and scalability. Systems are configured to have multiple connected cell culture chambers, which allows parallel processing of different types of cells. Gas-impermeable cell culture chambers and methods for generating cells in closed systems prevent contamination and user error. Methods for recycling cell culture medium provide additional efficiencies.
    Type: Application
    Filed: October 20, 2020
    Publication date: April 22, 2021
    Inventors: Shashi K. Murthy, Andrew Kozbial
  • Publication number: 20210115375
    Abstract: Cell culture systems and methods provide improved immunotherapeutic product manufacturing with greater scalability, flexibility, and automation. Cell culture systems are configured with interchangeable cartridges, allowing versatility and scalability. Systems are configured to have multiple connected cell culture chambers, which allows parallel processing of different types of cells. Gas-impermeable cell culture chambers and methods for generating cells in closed systems prevent contamination and user error. Methods for recycling cell culture medium provide additional efficiencies.
    Type: Application
    Filed: October 20, 2020
    Publication date: April 22, 2021
    Inventors: Shashi K. Murthy, Andrew Kozbial
  • Publication number: 20210115382
    Abstract: Cell culture systems and methods provide improved immunotherapeutic product manufacturing with greater scalability, flexibility, and automation. Cell culture systems are configured with interchangeable cartridges, allowing versatility and scalability. Systems are configured to have multiple connected cell culture chambers, which allows parallel processing of different types of cells. Gas-impermeable cell culture chambers and methods for generating cells in closed systems prevent contamination and user error. Methods for recycling cell culture medium provide additional efficiencies.
    Type: Application
    Filed: October 20, 2020
    Publication date: April 22, 2021
    Inventors: Shashi K. Murthy, Andrew Kozbial
  • Publication number: 20210115372
    Abstract: Cell culture systems and methods provide improved immunotherapeutic product manufacturing with greater scalability, flexibility, and automation. Cell culture systems are configured with interchangeable cartridges, allowing versatility and scalability. Systems are configured to have multiple connected cell culture chambers, which allows parallel processing of different types of cells. Gas-impermeable cell culture chambers and methods for generating cells in closed systems prevent contamination and user error. Methods for recycling cell culture medium provide additional efficiencies.
    Type: Application
    Filed: October 20, 2020
    Publication date: April 22, 2021
    Inventors: Shashi K. Murthy, Andrew Kozbial
  • Publication number: 20210115373
    Abstract: Cell culture systems and methods provide improved immunotherapeutic product manufacturing with greater scalability, flexibility, and automation. Cell culture systems are configured with interchangeable cartridges, allowing versatility and scalability. Systems are configured to have multiple connected cell culture chambers, which allows parallel processing of different types of cells. Gas-impermeable cell culture chambers and methods for generating cells in closed systems prevent contamination and user error. Methods for recycling cell culture medium provide additional efficiencies.
    Type: Application
    Filed: October 20, 2020
    Publication date: April 22, 2021
    Inventors: Shashi K. Murthy, Andrew Kozbial
  • Publication number: 20210115384
    Abstract: Cell culture systems and methods provide improved immunotherapeutic product manufacturing with greater scalability, flexibility, and automation. Cell culture systems are configured with interchangeable cartridges, allowing versatility and scalability. Systems are configured to have multiple connected cell culture chambers, which allows parallel processing of different types of cells. Gas-impermeable cell culture chambers and methods for generating cells in closed systems prevent contamination and user error. Methods for recycling cell culture medium provide additional efficiencies.
    Type: Application
    Filed: October 20, 2020
    Publication date: April 22, 2021
    Inventors: Shashi K. Murthy, Andrew Kozbial
  • Publication number: 20200231918
    Abstract: A cell culture cartridge is provided comprising a plurality of zones geometrically configured to provide for symmetrical fluid flow with each of the plurality of zones to avoid dead areas in flow within each of the plurality of zones. In certain embodiments, at least eight inlets are provided, with an inlet positioned at each corner of the cell culture cartridge. In certain embodiments, a shared outlet is positioned on a top surface of the cell culture cartridge.
    Type: Application
    Filed: April 6, 2020
    Publication date: July 23, 2020
    Inventor: Andrew Kozbial
  • Publication number: 20200157484
    Abstract: A cell culture cartridge is provided comprising a plurality of zones geometrically configured to provide for symmetrical fluid flow with each of the plurality of zones to avoid dead areas in flow within each of the plurality of zones. In certain embodiments, at least eight inlets are provided, with an inlet positioned at each corner of the cell culture cartridge. In certain embodiments, a shared outlet is positioned on a top surface of the cell culture cartridge.
    Type: Application
    Filed: November 15, 2018
    Publication date: May 21, 2020
    Inventor: Andrew Kozbial
  • Patent number: 10647954
    Abstract: A cell culture cartridge is provided comprising a plurality of zones geometrically configured to provide for symmetrical fluid flow with each of the plurality of zones to avoid dead areas in flow within each of the plurality of zones. In certain embodiments, at least eight inlets are provided, with an inlet positioned at each corner of the cell culture cartridge. In certain embodiments, a shared outlet is positioned on a top surface of the cell culture cartridge.
    Type: Grant
    Filed: November 15, 2018
    Date of Patent: May 12, 2020
    Assignee: FLASKWORKS, LLC
    Inventor: Andrew Kozbial