Patents by Inventor Andrew Kucerovy

Andrew Kucerovy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Improved process for preparing polymyxin B/dextran conjugates
    Patent number: 5691304
    Abstract: An improved process for producing a water-soluble polymyxin B/dextran conjugate comprises the step of reacting polymyxin B or pharmaceutically acceptable salt thereof with dextran in an aqueous media at a pH of about 9.3 to 10.
    Type: Grant
    Filed: May 25, 1995
    Date of Patent: November 25, 1997
    Assignee: Novartis AG
    Inventors: Prasad Kapa, Gleb Kardash, Andrew Kucerovy, Philip Lake, Paul G. Mattner, Russell C. Petter, Mahavir Prashad, Sushil Sharma
  • Process for preparing 1,4,8,11-tetraazacyclotetradecane
    Patent number: 5608061
    Abstract: An improved process for preparing 1,4,8,11-tetraazacyclotetradecane comprising the tetratosylation of an acyclic tetraamine to obtain a tetratoluenesulfonamide compound in a first step, the cyclization of said sulfonamide compound to obtain tetratosyl cyclam in a second step, and the detosylation of tetratosyl cyclam in a third step followed by basification to obtain the desired 1,4,8,11-tetraazacyclotetradecane.
    Type: Grant
    Filed: August 2, 1995
    Date of Patent: March 4, 1997
    Assignee: Johnson Matthey PLC
    Inventors: Lech Ciszewski, John Amedio, Prasad Kapa, Andrew Kucerovy, George T. Lee