Patents by Inventor Andrew KWON

Andrew KWON has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATION THERAPIES FOR THE TREATMENT OF CANCER
    Publication number: 20260137665
    Abstract: Provided are methods of treating cancer (e.g, a cancer that comprises one or more cancer cells that express a KRAS G12C mutant protein and/or have at least one mTOR-activating aberration) in an individual that comprise administering a composition comprising nanoparticles that comprise an mTOR inhibitor (such as a limus drug, e.g, sirolimus or a derivative thereof) and an albumin in combination with a KRAS G12C inhibitor to the individual. Also provided are related kits.
    Type: Application
    Filed: October 10, 2023
    Publication date: May 21, 2026
    Inventors: Shihe HOU, Andrew KWON, Neil P. DESAI
  • BIOMARKERS FOR NANOPARTICLE COMPOSITIONS
    Publication number: 20230293449
    Abstract: The present application provides methods and compositions for treating cancer by administering a composition comprising nanoparticles that comprise an mTOR inhibitor (such as a limus drug) and a carrier protein (such as an albumin) based upon the status of one or more mTOR-activating aberration at one or more genes selected from the group consisting of TSC1, TSC2, RPS6, PTEN, TP53, RB1, ATRX, and FAT1.
    Type: Application
    Filed: December 19, 2022
    Publication date: September 21, 2023
    Inventors: Neil P. DESAI, Anita N. SCHMID, Shihe HOU, Andrew KWON
  • BIOMARKERS FOR NANOPARTICLE COMPOSITIONS
    Publication number: 20230000844
    Abstract: The present application provides methods and compositions for treating cancer by administering a composition comprising nanoparticles that comprise an mTOR inhibitor (such as a limus drug) and a carrier protein (such as an albumin) based upon the mutation status of TSC1 or TSC2 and one of VHL, RBI, PBRIM1, K.DM6A, RET, SETD2 ARID 1 A, BAP1, BRCA2, TP53, RBI, ATRX, FLT1, NTRK1, TLX3, KDM6A, CDH4, CDKN2C, DAXX, ERBB3, GNAS, IL7R, PDGFRB, PMS2, PTEN, SMARCA4, and YY1AP1.
    Type: Application
    Filed: November 11, 2020
    Publication date: January 5, 2023
    Inventors: Neil P. DESAI, Anita N. SCHMID, Shihe HOU, Andrew KWON
  • BIOMARKERS FOR NANOPARTICLE COMPOSITIONS
    Publication number: 20210137848
    Abstract: The present application provides methods and compositions for treating cancer by administering a composition comprising nanoparticles that comprise an mTOR inhibitor (such as a limus drug) and a carrier protein (such as an albumin) based upon the status of one or more mTOR-activating aberration at one or more genes selected from the group consisting of TSC1, TSC2, RPS6, PTEN, TP53, RB1, ATRX, and FAT1.
    Type: Application
    Filed: December 2, 2020
    Publication date: May 13, 2021
    Inventors: Neil P. DESAI, Anita N. SCHMID, Shihe HOU, Andrew KWON